ENSG00000158669

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000396987 ENSG00000158669 No_inf pgKDN_inf GPAT4 protein_coding protein_coding 136.9925 116.2884 147.8361 4.481868 2.405946 0.3462652 12.493005 7.670421 15.018713 0.4629434 0.3274647 0.9684642 0.08980000 0.066600 0.101775 0.035175 0.47099745 0.02256969 FALSE  
ENST00000519853 ENSG00000158669 No_inf pgKDN_inf GPAT4 protein_coding protein_coding 136.9925 116.2884 147.8361 4.481868 2.405946 0.3462652 17.075750 13.336369 18.353680 1.7061395 3.3539423 0.4604079 0.12389167 0.113825 0.124850 0.011025 0.98667880 0.02256969 FALSE  
ENST00000519921 ENSG00000158669 No_inf pgKDN_inf GPAT4 protein_coding retained_intron 136.9925 116.2884 147.8361 4.481868 2.405946 0.3462652 5.632009 9.274829 3.325167 0.7756011 0.8085355 -1.4771165 0.04376667 0.079550 0.022325 -0.057225 0.02256969 0.02256969 FALSE  
ENST00000520223 ENSG00000158669 No_inf pgKDN_inf GPAT4 protein_coding protein_coding 136.9925 116.2884 147.8361 4.481868 2.405946 0.3462652 18.669090 12.953582 21.531240 1.1521471 3.0594439 0.7326369 0.13437500 0.110775 0.145350 0.034575 0.76221083 0.02256969 FALSE  
ENST00000521806 ENSG00000158669 No_inf pgKDN_inf GPAT4 protein_coding nonsense_mediated_decay 136.9925 116.2884 147.8361 4.481868 2.405946 0.3462652 21.439978 16.596544 27.339778 0.7380046 2.2356925 0.7197773 0.15542500 0.142775 0.184625 0.041850 0.59442487 0.02256969 TRUE  
ENST00000523906 ENSG00000158669 No_inf pgKDN_inf GPAT4 protein_coding retained_intron 136.9925 116.2884 147.8361 4.481868 2.405946 0.3462652 53.503447 45.836836 55.173418 2.0171246 2.4596503 0.2674126 0.39052500 0.394075 0.373125 -0.020950 0.85935795 0.02256969 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000158669 E001 0.2459004 0.0165158410 9.969349e-01   8 41577187 41577435 249 + 0.095 0.095 -0.008
ENSG00000158669 E002 0.1176306 0.0117522677 5.359094e-01   8 41578169 41578187 19 + 0.095 0.000 -12.521
ENSG00000158669 E003 0.9598730 0.0965710435 1.939803e-01 4.737705e-01 8 41578188 41578199 12 + 0.393 0.173 -1.592
ENSG00000158669 E004 0.9598730 0.0965710435 1.939803e-01 4.737705e-01 8 41578200 41578205 6 + 0.393 0.173 -1.592
ENSG00000158669 E005 1.9568545 0.1688582663 9.721361e-01 9.947660e-01 8 41578206 41578214 9 + 0.472 0.470 -0.008
ENSG00000158669 E006 5.3572104 0.0751331908 5.021851e-01 7.619663e-01 8 41578215 41578242 28 + 0.853 0.751 -0.403
ENSG00000158669 E007 11.8218892 0.0120616681 3.258570e-01 6.183415e-01 8 41578243 41578278 36 + 1.154 1.061 -0.336
ENSG00000158669 E008 0.3812526 0.0158587128 1.038333e-01   8 41578415 41578580 166 + 0.000 0.239 13.194
ENSG00000158669 E009 0.0000000       8 41584772 41584772 1 +      
ENSG00000158669 E010 0.4798448 0.0153047124 3.173056e-01   8 41584773 41584917 145 + 0.240 0.095 -1.593
ENSG00000158669 E011 42.0422373 0.0107576687 7.875773e-02 2.876689e-01 8 41598292 41598476 185 + 1.689 1.575 -0.386
ENSG00000158669 E012 134.1438820 0.0007656301 6.878818e-05 1.729614e-03 8 41598477 41599047 571 + 2.182 2.076 -0.356
ENSG00000158669 E013 67.6855490 0.0002138823 1.074695e-01 3.436247e-01 8 41599048 41599233 186 + 1.866 1.808 -0.195
ENSG00000158669 E014 45.3042926 0.0003194294 9.671547e-01 9.933727e-01 8 41599234 41599304 71 + 1.667 1.664 -0.008
ENSG00000158669 E015 40.4813890 0.0003554022 4.485790e-01 7.225655e-01 8 41609416 41609485 70 + 1.636 1.600 -0.121
ENSG00000158669 E016 14.5646807 0.0032517521 7.702700e-01 9.114498e-01 8 41609655 41609783 129 + 1.203 1.181 -0.081
ENSG00000158669 E017 21.3809410 0.0056129163 5.256449e-01 7.783029e-01 8 41609784 41609955 172 + 1.372 1.328 -0.156
ENSG00000158669 E018 16.1488063 0.0008299741 8.921335e-13 1.182219e-10 8 41609956 41610255 300 + 0.853 1.421 2.049
ENSG00000158669 E019 15.7148788 0.0111122313 1.030412e-06 4.795015e-05 8 41610256 41610598 343 + 0.947 1.379 1.547
ENSG00000158669 E020 2.7394743 0.0050308288 3.268088e-02 1.713768e-01 8 41610599 41610621 23 + 0.393 0.691 1.407
ENSG00000158669 E021 6.4906847 0.0179208853 3.145254e-04 6.033899e-03 8 41610622 41610735 114 + 0.596 1.032 1.729
ENSG00000158669 E022 26.7363030 0.0006103685 5.205677e-01 7.748393e-01 8 41610736 41610777 42 + 1.424 1.460 0.125
ENSG00000158669 E023 31.8104968 0.0004933489 6.838635e-01 8.691762e-01 8 41610778 41610810 33 + 1.527 1.505 -0.074
ENSG00000158669 E024 0.3539644 0.0269438872 1.039005e-01   8 41610811 41610812 2 + 0.240 0.000 -13.915
ENSG00000158669 E025 52.4425201 0.0003409706 2.440913e-01 5.341998e-01 8 41611903 41611992 90 + 1.752 1.704 -0.163
ENSG00000158669 E026 51.0742205 0.0004160756 1.287609e-01 3.806089e-01 8 41612180 41612273 94 + 1.748 1.684 -0.215
ENSG00000158669 E027 0.2374063 0.2906687774 3.061814e-01   8 41612786 41612844 59 + 0.174 0.000 -12.336
ENSG00000158669 E028 77.0663247 0.0002131277 1.841679e-01 4.612700e-01 8 41612845 41612960 116 + 1.869 1.913 0.149
ENSG00000158669 E029 54.0495706 0.0002952385 4.158164e-01 6.958363e-01 8 41614386 41614441 56 + 1.757 1.724 -0.112
ENSG00000158669 E030 64.6803153 0.0006001970 4.352606e-01 7.121726e-01 8 41614963 41615048 86 + 1.832 1.803 -0.100
ENSG00000158669 E031 6.3939212 0.0025861973 2.149956e-06 9.040287e-05 8 41618532 41618683 152 + 0.506 1.051 2.215
ENSG00000158669 E032 38.9895018 0.0087169046 5.987688e-01 8.240431e-01 8 41618684 41618705 22 + 1.586 1.616 0.102
ENSG00000158669 E033 67.3790909 0.0006450463 2.672116e-01 5.604226e-01 8 41618706 41618812 107 + 1.855 1.814 -0.139
ENSG00000158669 E034 0.2374063 0.2906687774 3.061814e-01   8 41618813 41618813 1 + 0.174 0.000 -12.336
ENSG00000158669 E035 50.5805896 0.0003013867 9.172855e-01 9.740263e-01 8 41618898 41618977 80 + 1.710 1.714 0.013
ENSG00000158669 E036 1.9953225 0.0070337037 4.417848e-02 2.055528e-01 8 41618978 41619351 374 + 0.297 0.594 1.577
ENSG00000158669 E037 164.6500862 0.0003922660 4.503079e-04 8.052687e-03 8 41620893 41625001 4109 + 2.175 2.256 0.269

Help

Please Click HERE to learn more details about the results from DEXseq.