ENSG00000158863

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000289921 ENSG00000158863 No_inf pgKDN_inf FHIP2B protein_coding protein_coding 36.53818 51.95305 21.48369 3.514519 1.373777 -1.273573 7.114509 8.948240 5.1233915 0.6844327 1.7941957 -0.8033030 0.20670000 0.177325 0.239575 0.062250 0.98544294 0.03531654 FALSE TRUE
ENST00000462914 ENSG00000158863 No_inf pgKDN_inf FHIP2B protein_coding retained_intron 36.53818 51.95305 21.48369 3.514519 1.373777 -1.273573 4.868842 6.686281 0.3430262 1.0884301 0.3430262 -4.2455130 0.11685833 0.127150 0.016450 -0.110700 0.03531654 0.03531654 FALSE FALSE
ENST00000477614 ENSG00000158863 No_inf pgKDN_inf FHIP2B protein_coding retained_intron 36.53818 51.95305 21.48369 3.514519 1.373777 -1.273573 6.095930 9.456067 3.4763572 1.2590112 0.2645474 -1.4410448 0.16331667 0.180750 0.162875 -0.017875 0.92276407 0.03531654 FALSE FALSE
ENST00000496599 ENSG00000158863 No_inf pgKDN_inf FHIP2B protein_coding retained_intron 36.53818 51.95305 21.48369 3.514519 1.373777 -1.273573 2.827279 4.258607 1.3466967 0.7218405 0.2456169 -1.6536672 0.07637500 0.084225 0.065400 -0.018825 0.88252133 0.03531654 FALSE TRUE
ENST00000523633 ENSG00000158863 No_inf pgKDN_inf FHIP2B protein_coding retained_intron 36.53818 51.95305 21.48369 3.514519 1.373777 -1.273573 8.294061 10.771462 5.4365765 1.7196478 0.8145021 -0.9851312 0.23119167 0.203350 0.249400 0.046050 0.83437237 0.03531654 FALSE FALSE
MSTRG.27365.3 ENSG00000158863 No_inf pgKDN_inf FHIP2B protein_coding   36.53818 51.95305 21.48369 3.514519 1.373777 -1.273573 2.217117 4.285973 1.0136610 0.6209798 0.3967399 -2.0692469 0.05456667 0.081400 0.045800 -0.035600 0.70251773 0.03531654 FALSE TRUE
MSTRG.27365.4 ENSG00000158863 No_inf pgKDN_inf FHIP2B protein_coding   36.53818 51.95305 21.48369 3.514519 1.373777 -1.273573 0.672812 0.000000 2.0184360 0.0000000 1.7763025 7.6642239 0.03250000 0.000000 0.097500 0.097500 0.37430451 0.03531654 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000158863 E001 0.2444846 0.0163334352 5.547691e-01   8 22089150 22089158 9 + 0.133 0.067 -1.091
ENSG00000158863 E002 0.7535340 0.3516207021 6.050355e-01 0.827821460 8 22089159 22089163 5 + 0.133 0.265 1.232
ENSG00000158863 E003 1.2425646 0.4853726730 8.805889e-01 0.959793856 8 22089164 22089169 6 + 0.316 0.337 0.133
ENSG00000158863 E004 2.5818411 0.1154621713 3.951152e-01 0.679897063 8 22089170 22089183 14 + 0.625 0.479 -0.675
ENSG00000158863 E005 3.2082389 0.0467966995 5.357460e-01 0.785325308 8 22089184 22089202 19 + 0.660 0.566 -0.412
ENSG00000158863 E006 3.2082389 0.0467966995 5.357460e-01 0.785325308 8 22089203 22089207 5 + 0.660 0.566 -0.412
ENSG00000158863 E007 6.4173859 0.0040423850 3.308480e-01 0.623152520 8 22089208 22089298 91 + 0.911 0.804 -0.413
ENSG00000158863 E008 0.9980213 0.0134151846 6.703758e-01 0.863038906 8 22089761 22089854 94 + 0.234 0.302 0.494
ENSG00000158863 E009 6.9240834 0.0070667939 5.607971e-01 0.801241389 8 22094440 22094518 79 + 0.911 0.847 -0.243
ENSG00000158863 E010 3.4865242 0.0050536024 7.022610e-01 0.878848695 8 22094519 22096336 1818 + 0.586 0.639 0.231
ENSG00000158863 E011 12.6399944 0.0011655995 7.632268e-01 0.907692931 8 22096337 22096509 173 + 1.119 1.094 -0.091
ENSG00000158863 E012 1.8678388 0.0073764411 6.594277e-01 0.857890315 8 22096510 22096543 34 + 0.385 0.454 0.368
ENSG00000158863 E013 18.0648650 0.0009037888 6.998474e-05 0.001753976 8 22096544 22097515 972 + 0.997 1.321 1.160
ENSG00000158863 E014 6.4223894 0.0445389688 4.083329e-01 0.690680088 8 22097516 22097565 50 + 0.911 0.804 -0.414
ENSG00000158863 E015 7.7972315 0.0071159060 6.239565e-01 0.838178091 8 22097566 22097620 55 + 0.947 0.896 -0.193
ENSG00000158863 E016 1.2354896 0.0660811073 6.033238e-01 0.826996042 8 22097621 22097716 96 + 0.385 0.302 -0.506
ENSG00000158863 E017 14.6816467 0.0033057365 3.637237e-01 0.652625426 8 22097717 22097839 123 + 1.107 1.183 0.274
ENSG00000158863 E018 0.5079160 0.1649293284 2.588808e-01 0.551413695 8 22097935 22098067 133 + 0.000 0.223 9.647
ENSG00000158863 E019 21.2210693 0.0006618063 9.180031e-01 0.974222842 8 22098068 22098310 243 + 1.307 1.314 0.025
ENSG00000158863 E020 18.9202473 0.0007692038 2.191434e-01 0.505810653 8 22098423 22098619 197 + 1.322 1.237 -0.298
ENSG00000158863 E021 12.9894249 0.0011649707 3.555318e-01 0.645305493 8 22098948 22099056 109 + 1.164 1.088 -0.273
ENSG00000158863 E022 0.0000000       8 22099057 22099124 68 +      
ENSG00000158863 E023 12.5528876 0.0018418536 7.885294e-01 0.918904677 8 22099284 22099360 77 + 1.082 1.105 0.084
ENSG00000158863 E024 14.4092260 0.0011010751 8.317265e-01 0.939264531 8 22099704 22099818 115 + 1.142 1.159 0.061
ENSG00000158863 E025 10.0361102 0.0092856522 8.146614e-01 0.932350434 8 22099819 22099893 75 + 1.027 1.002 -0.091
ENSG00000158863 E026 1.8446655 0.0081326531 2.424480e-01 0.532114893 8 22100138 22100593 456 + 0.544 0.370 -0.898
ENSG00000158863 E027 16.2383588 0.0035697045 8.344994e-01 0.940355913 8 22100594 22100739 146 + 1.214 1.197 -0.058
ENSG00000158863 E028 18.9144521 0.0008470383 1.622624e-01 0.430680772 8 22100844 22100972 129 + 1.330 1.233 -0.339
ENSG00000158863 E029 5.0174548 0.0028171195 4.001904e-02 0.193954737 8 22100973 22101181 209 + 0.544 0.815 1.146
ENSG00000158863 E030 7.9573875 0.0084190262 5.335800e-01 0.784059044 8 22101190 22101439 250 + 0.871 0.940 0.263
ENSG00000158863 E031 13.0739256 0.0011465962 6.220767e-02 0.250437315 8 22101440 22101482 43 + 1.214 1.063 -0.540
ENSG00000158863 E032 11.7839736 0.0014306071 8.852196e-01 0.961367482 8 22101483 22101530 48 + 1.082 1.069 -0.045
ENSG00000158863 E033 24.9535653 0.0005649096 8.532741e-01 0.948218790 8 22101708 22101851 144 + 1.371 1.383 0.040
ENSG00000158863 E034 5.0054600 0.0031900105 9.386030e-02 0.318621703 8 22101852 22101991 140 + 0.586 0.804 0.909
ENSG00000158863 E035 4.7275208 0.0029584394 6.910836e-01 0.873235147 8 22101992 22102062 71 + 0.693 0.743 0.204
ENSG00000158863 E036 4.7542807 0.0061589316 1.427914e-01 0.402220172 8 22102063 22102174 112 + 0.586 0.780 0.816
ENSG00000158863 E037 23.1215146 0.0006299957 4.799361e-01 0.745471563 8 22102175 22102315 141 + 1.315 1.361 0.161
ENSG00000158863 E038 0.8812048 0.0255232446 2.977989e-01 0.590821672 8 22102527 22102527 1 + 0.133 0.302 1.494
ENSG00000158863 E039 21.8455383 0.0009446240 9.707196e-01 0.994185238 8 22102528 22102628 101 + 1.322 1.325 0.009
ENSG00000158863 E040 55.0931178 0.0002677641 9.843881e-01 0.998789600 8 22102793 22103185 393 + 1.714 1.713 -0.002
ENSG00000158863 E041 114.3615737 0.0001493943 7.245790e-01 0.889402216 8 22103186 22104068 883 + 2.033 2.023 -0.032
ENSG00000158863 E042 35.3540889 0.0004206216 9.001389e-01 0.967584718 8 22104069 22104911 843 + 1.530 1.523 -0.022

Help

Please Click HERE to learn more details about the results from DEXseq.