ENSG00000158941

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000308511 ENSG00000158941 No_inf pgKDN_inf CCAR2 protein_coding protein_coding 98.46776 95.64364 106.1064 5.155368 20.56365 0.1497563 31.626970 27.778448 38.536240 2.1608153 3.5704046 0.4721049 0.34537500 0.295050 0.423675 0.128625 0.755103152 0.001768609 FALSE  
ENST00000389279 ENSG00000158941 No_inf pgKDN_inf CCAR2 protein_coding protein_coding 98.46776 95.64364 106.1064 5.155368 20.56365 0.1497563 7.426919 3.003394 9.173368 0.7137700 1.2587990 1.6076340 0.07929167 0.031675 0.096700 0.065025 0.183845976 0.001768609 FALSE  
ENST00000518989 ENSG00000158941 No_inf pgKDN_inf CCAR2 protein_coding protein_coding 98.46776 95.64364 106.1064 5.155368 20.56365 0.1497563 2.150734 5.108499 0.000000 3.1975153 0.0000000 -8.9995770 0.02225000 0.050750 0.000000 -0.050750 0.470276867 0.001768609 FALSE  
ENST00000520536 ENSG00000158941 No_inf pgKDN_inf CCAR2 protein_coding retained_intron 98.46776 95.64364 106.1064 5.155368 20.56365 0.1497563 5.194912 9.156177 1.575668 1.3544802 0.4828711 -2.5312293 0.05400000 0.096575 0.014975 -0.081600 0.001768609 0.001768609    
ENST00000520738 ENSG00000158941 No_inf pgKDN_inf CCAR2 protein_coding protein_coding 98.46776 95.64364 106.1064 5.155368 20.56365 0.1497563 10.001826 15.270861 6.985388 1.9709314 4.4858490 -1.1272499 0.10107500 0.161175 0.051100 -0.110075 0.298355642 0.001768609 FALSE  
ENST00000521020 ENSG00000158941 No_inf pgKDN_inf CCAR2 protein_coding retained_intron 98.46776 95.64364 106.1064 5.155368 20.56365 0.1497563 7.768057 8.422833 5.536567 2.3873580 1.4881398 -0.6044223 0.08276667 0.089475 0.053775 -0.035700 0.824020795 0.001768609    
ENST00000521301 ENSG00000158941 No_inf pgKDN_inf CCAR2 protein_coding protein_coding 98.46776 95.64364 106.1064 5.155368 20.56365 0.1497563 21.134739 12.288364 35.267232 4.5066449 17.8936020 1.5202710 0.17709167 0.121475 0.272600 0.151125 0.863071637 0.001768609    
ENST00000522599 ENSG00000158941 No_inf pgKDN_inf CCAR2 protein_coding protein_coding 98.46776 95.64364 106.1064 5.155368 20.56365 0.1497563 4.918877 5.333727 3.874049 0.7346056 1.5181701 -0.4602848 0.05045000 0.056225 0.036550 -0.019675 0.792589094 0.001768609 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000158941 E001 1.7324867 0.0078779039 3.490361e-01 0.6395418828 8 22604744 22604756 13 + 0.355 0.496 0.751
ENSG00000158941 E002 2.4510922 0.0089704911 8.800201e-01 0.9595324700 8 22604757 22604762 6 + 0.548 0.527 -0.097
ENSG00000158941 E003 11.0871350 0.0200216045 1.173904e-01 0.3619560625 8 22604763 22604790 28 + 1.159 1.000 -0.577
ENSG00000158941 E004 21.0156217 0.0022164167 9.405667e-04 0.0143139170 8 22604791 22604842 52 + 1.445 1.227 -0.759
ENSG00000158941 E005 6.6020018 0.0203567557 4.493655e-05 0.0012209613 8 22605038 22605418 381 + 1.075 0.584 -1.938
ENSG00000158941 E006 1.7236692 0.0111867669 6.898538e-01 0.8725805721 8 22605500 22605559 60 + 0.401 0.461 0.318
ENSG00000158941 E007 0.6165451 0.0210783612 7.137169e-01 0.8846930461 8 22605719 22605735 17 + 0.178 0.233 0.488
ENSG00000158941 E008 34.5170043 0.0004538838 5.581296e-05 0.0014591451 8 22605736 22605831 96 + 1.646 1.443 -0.694
ENSG00000158941 E009 35.6600113 0.0003989561 5.349492e-04 0.0092061111 8 22606085 22606176 92 + 1.646 1.475 -0.584
ENSG00000158941 E010 0.1186381 0.0118331423 5.022469e-01   8 22606600 22606606 7 + 0.098 0.000 -9.224
ENSG00000158941 E011 37.0369198 0.0004012601 2.547169e-03 0.0305218810 8 22606607 22606698 92 + 1.651 1.505 -0.498
ENSG00000158941 E012 0.0000000       8 22606699 22606703 5 +      
ENSG00000158941 E013 0.0000000       8 22606908 22606909 2 +      
ENSG00000158941 E014 44.0681160 0.0009211084 3.945792e-01 0.6793907864 8 22606910 22607024 115 + 1.673 1.635 -0.129
ENSG00000158941 E015 24.5648589 0.0029081161 2.310790e-01 0.5195381267 8 22607196 22607235 40 + 1.445 1.371 -0.255
ENSG00000158941 E016 40.0083673 0.0050468548 7.483904e-01 0.9006886258 8 22607236 22607325 90 + 1.602 1.620 0.063
ENSG00000158941 E017 47.0831818 0.0010394137 9.489750e-01 0.9867620019 8 22607969 22608065 97 + 1.682 1.680 -0.007
ENSG00000158941 E018 0.6255163 0.0148828646 1.980127e-01 0.4793884641 8 22608066 22608077 12 + 0.098 0.289 1.903
ENSG00000158941 E019 9.0581820 0.0031298054 4.521489e-03 0.0461623008 8 22612703 22613016 314 + 0.834 1.108 1.024
ENSG00000158941 E020 38.9291369 0.0006400019 2.609077e-02 0.1493964993 8 22613017 22613136 120 + 1.654 1.548 -0.360
ENSG00000158941 E021 1.3500979 0.0102738295 8.536020e-01 0.9483215821 8 22613885 22614091 207 + 0.355 0.384 0.166
ENSG00000158941 E022 0.0000000       8 22614092 22614314 223 +      
ENSG00000158941 E023 0.0000000       8 22614388 22614389 2 +      
ENSG00000158941 E024 0.0000000       8 22614390 22614503 114 +      
ENSG00000158941 E025 0.0000000       8 22614504 22614573 70 +      
ENSG00000158941 E026 0.0000000       8 22614838 22615001 164 +      
ENSG00000158941 E027 0.0000000       8 22615425 22615517 93 +      
ENSG00000158941 E028 0.0000000       8 22615518 22615596 79 +      
ENSG00000158941 E029 0.0000000       8 22615682 22615801 120 +      
ENSG00000158941 E030 0.0000000       8 22615802 22615912 111 +      
ENSG00000158941 E031 0.0000000       8 22616012 22616248 237 +      
ENSG00000158941 E032 2.7045382 0.0097093741 7.955710e-01 0.9223427071 8 22617388 22617419 32 + 0.548 0.584 0.166
ENSG00000158941 E033 54.3475934 0.0002718800 7.858909e-01 0.9174873340 8 22617420 22617564 145 + 1.736 1.748 0.040
ENSG00000158941 E034 28.5878993 0.0011822382 8.515391e-01 0.9474745986 8 22617696 22617698 3 + 1.464 1.475 0.040
ENSG00000158941 E035 58.5448510 0.0004051585 5.048451e-01 0.7638469018 8 22617699 22617778 80 + 1.787 1.762 -0.085
ENSG00000158941 E036 7.1285115 0.0033432157 2.956764e-05 0.0008564453 8 22618157 22618348 192 + 0.606 1.066 1.810
ENSG00000158941 E037 80.1798312 0.0002032999 9.553941e-01 0.9892342829 8 22618349 22618495 147 + 1.907 1.910 0.009
ENSG00000158941 E038 56.6747696 0.0004399861 7.075008e-01 0.8813162256 8 22618617 22618728 112 + 1.752 1.767 0.053
ENSG00000158941 E039 1.5976392 0.0084031541 8.800370e-01 0.9595324700 8 22618729 22618826 98 + 0.401 0.424 0.126
ENSG00000158941 E040 84.8454570 0.0002547435 9.976515e-01 1.0000000000 8 22618827 22619015 189 + 1.932 1.933 0.003
ENSG00000158941 E041 94.1796260 0.0001885672 8.407978e-01 0.9429091111 8 22619150 22619355 206 + 1.974 1.981 0.024
ENSG00000158941 E042 13.9399631 0.0301941027 4.524588e-04 0.0080831115 8 22619356 22619637 282 + 0.934 1.310 1.354
ENSG00000158941 E043 396.1070971 0.0001143575 3.911618e-06 0.0001521047 8 22619638 22620964 1327 + 2.564 2.625 0.203

Help

Please Click HERE to learn more details about the results from DEXseq.