ENSG00000159086

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000331923 ENSG00000159086 No_inf pgKDN_inf PAXBP1 protein_coding protein_coding 20.2809 26.73996 18.06202 3.585721 0.9158479 -0.5657786 4.545400 3.123066 5.795313 0.8153252 0.4386387 0.8897986 0.24337500 0.111975 0.322875 0.210900 0.0269477 0.0269477 FALSE TRUE
ENST00000421049 ENSG00000159086 No_inf pgKDN_inf PAXBP1 protein_coding nonsense_mediated_decay 20.2809 26.73996 18.06202 3.585721 0.9158479 -0.5657786 1.700576 3.906045 1.195683 3.9060454 0.7023622 -1.6995473 0.05571667 0.104825 0.062325 -0.042500 0.8124738 0.0269477   FALSE
ENST00000466846 ENSG00000159086 No_inf pgKDN_inf PAXBP1 protein_coding retained_intron 20.2809 26.73996 18.06202 3.585721 0.9158479 -0.5657786 6.236483 9.111661 4.870866 0.5360275 0.1791536 -0.9021595 0.30927500 0.362350 0.270825 -0.091525 0.8001814 0.0269477 FALSE TRUE
ENST00000497873 ENSG00000159086 No_inf pgKDN_inf PAXBP1 protein_coding retained_intron 20.2809 26.73996 18.06202 3.585721 0.9158479 -0.5657786 2.553553 3.200034 2.684446 0.2442068 0.5102627 -0.2526000 0.12840000 0.124700 0.150625 0.025925 0.9017473 0.0269477 FALSE TRUE
MSTRG.18724.2 ENSG00000159086 No_inf pgKDN_inf PAXBP1 protein_coding   20.2809 26.73996 18.06202 3.585721 0.9158479 -0.5657786 4.227956 6.254418 2.863724 0.5494196 0.2283565 -1.1242590 0.20958333 0.248200 0.157850 -0.090350 0.6855802 0.0269477 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000159086 E001 0.000000       21 32733899 32733899 1 -      
ENSG00000159086 E002 88.708132 0.0007723208 0.1377441437 0.3950394414 21 32733900 32734819 920 - 1.907 1.955 0.160
ENSG00000159086 E003 8.492576 0.0016552346 0.4219048236 0.7011250888 21 32734820 32734825 6 - 1.010 0.934 -0.284
ENSG00000159086 E004 32.089804 0.0004894606 0.7619223903 0.9071580045 21 32734826 32735067 242 - 1.515 1.499 -0.055
ENSG00000159086 E005 11.097082 0.0078339704 0.6531291797 0.8541675358 21 32737254 32737408 155 - 1.093 1.054 -0.144
ENSG00000159086 E006 3.837691 0.0037543423 0.7122049463 0.8837720298 21 32738173 32738319 147 - 0.642 0.689 0.200
ENSG00000159086 E007 0.000000       21 32741393 32741418 26 -      
ENSG00000159086 E008 0.000000       21 32741419 32741622 204 -      
ENSG00000159086 E009 0.000000       21 32742360 32742501 142 -      
ENSG00000159086 E010 0.000000       21 32742961 32743066 106 -      
ENSG00000159086 E011 0.000000       21 32743248 32743314 67 -      
ENSG00000159086 E012 9.016109 0.0015632007 0.9493190386 0.9867638334 21 32743678 32743754 77 - 0.983 0.989 0.022
ENSG00000159086 E013 22.481452 0.0006123682 0.8208658713 0.9350145039 21 32744792 32744913 122 - 1.347 1.361 0.049
ENSG00000159086 E014 24.362109 0.0005581063 0.5250701771 0.7779229205 21 32745574 32745718 145 - 1.365 1.403 0.133
ENSG00000159086 E015 0.253014 0.2465710725 0.5046815225   21 32748222 32748248 27 - 0.000 0.143 8.959
ENSG00000159086 E016 11.545506 0.0012216039 0.1667111627 0.4370697963 21 32748499 32748558 60 - 1.154 1.038 -0.417
ENSG00000159086 E017 19.196609 0.0007724515 0.2410150193 0.5303510425 21 32748559 32748698 140 - 1.239 1.319 0.282
ENSG00000159086 E018 16.945704 0.0008401506 0.4737408245 0.7407089063 21 32750917 32751032 116 - 1.207 1.258 0.182
ENSG00000159086 E019 16.499224 0.0013038804 0.4704422435 0.7381210934 21 32751119 32751218 100 - 1.261 1.209 -0.185
ENSG00000159086 E020 13.746962 0.0010923388 0.0974936472 0.3253649134 21 32751219 32752124 906 - 1.231 1.103 -0.456
ENSG00000159086 E021 5.007231 0.0030337083 0.0115594781 0.0884952292 21 32755213 32755229 17 - 0.540 0.859 1.337
ENSG00000159086 E022 17.000950 0.0095449180 0.6062061998 0.8285217470 21 32755230 32755353 124 - 1.268 1.224 -0.155
ENSG00000159086 E023 45.591018 0.0025832166 0.0714594635 0.2708521623 21 32755354 32756341 988 - 1.597 1.684 0.296
ENSG00000159086 E024 3.469435 0.0042853016 0.4727712624 0.7399786191 21 32756342 32756368 27 - 0.577 0.672 0.415
ENSG00000159086 E025 71.080518 0.0008922276 0.0325245832 0.1708644566 21 32756369 32758612 2244 - 1.792 1.870 0.263
ENSG00000159086 E026 14.470077 0.0032337872 0.0617348558 0.2496353634 21 32759080 32759269 190 - 1.261 1.116 -0.516
ENSG00000159086 E027 4.965339 0.0028889544 0.2528274227 0.5441216397 21 32759270 32759401 132 - 0.672 0.809 0.560
ENSG00000159086 E028 10.620348 0.0013062107 0.9467955882 0.9858387052 21 32759402 32759776 375 - 1.048 1.053 0.021
ENSG00000159086 E029 15.849109 0.0119777577 0.2172945440 0.5036692196 21 32759777 32759994 218 - 1.276 1.171 -0.371
ENSG00000159086 E030 12.149955 0.0032231351 0.1278858613 0.3790594875 21 32761059 32761162 104 - 1.181 1.053 -0.458
ENSG00000159086 E031 15.952230 0.0008894418 0.0000177227 0.0005563772 21 32762096 32762317 222 - 1.382 1.075 -1.084
ENSG00000159086 E032 10.605688 0.0012896296 0.7076162805 0.8813175798 21 32764348 32764524 177 - 1.071 1.038 -0.120
ENSG00000159086 E033 6.684941 0.0022750112 0.5943906476 0.8216153040 21 32769814 32769942 129 - 0.836 0.893 0.219
ENSG00000159086 E034 11.502492 0.0140177518 0.0326987518 0.1714372001 21 32771326 32771792 467 - 1.198 0.998 -0.724

Help

Please Click HERE to learn more details about the results from DEXseq.