ENSG00000159111

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000351111 ENSG00000159111 No_inf pgKDN_inf MRPL10 protein_coding protein_coding 21.82185 21.1396 23.69238 0.8477557 1.262148 0.1644016 11.095062 12.272957 10.769438 1.477694 1.078885 -0.18837591 0.5199000 0.583600 0.462775 -0.120825 0.75373213 0.02066235 FALSE TRUE
ENST00000414011 ENSG00000159111 No_inf pgKDN_inf MRPL10 protein_coding protein_coding 21.82185 21.1396 23.69238 0.8477557 1.262148 0.1644016 4.802102 4.810792 4.580900 2.794191 2.689049 -0.07049316 0.2084167 0.218500 0.177950 -0.040550 1.00000000 0.02066235 FALSE TRUE
ENST00000421763 ENSG00000159111 No_inf pgKDN_inf MRPL10 protein_coding nonsense_mediated_decay 21.82185 21.1396 23.69238 0.8477557 1.262148 0.1644016 3.180668 2.326464 3.861790 1.704606 1.537088 0.72867372 0.1557833 0.118175 0.174625 0.056450 0.81953317 0.02066235 FALSE TRUE
ENST00000466016 ENSG00000159111 No_inf pgKDN_inf MRPL10 protein_coding retained_intron 21.82185 21.1396 23.69238 0.8477557 1.262148 0.1644016 1.773478 0.000000 3.704828 0.000000 1.310046 8.53715169 0.0706250 0.000000 0.148975 0.148975 0.02066235 0.02066235 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000159111 E001 0.2541163 0.0161962220 0.304101764   17 47823272 47823460 189 - 0.000 0.161 9.615
ENSG00000159111 E002 2.1133287 0.0064846082 0.170070427 0.44217983 17 47823461 47823489 29 - 0.367 0.568 1.022
ENSG00000159111 E003 8.7612940 0.0016884123 0.276517149 0.57006053 17 47823490 47823582 93 - 0.927 1.029 0.378
ENSG00000159111 E004 100.4701288 0.0002551012 0.900173865 0.96758472 17 47823583 47824458 876 - 2.005 2.002 -0.008
ENSG00000159111 E005 19.5097719 0.0007538716 0.009769001 0.07909742 17 47826637 47826781 145 - 1.392 1.230 -0.567
ENSG00000159111 E006 0.5967838 0.0150144696 0.121867065 0.36939510 17 47826895 47827039 145 - 0.315 0.088 -2.241
ENSG00000159111 E007 9.4069768 0.0016724656 0.186250952 0.46409142 17 47827040 47827073 34 - 1.076 0.959 -0.429
ENSG00000159111 E008 23.1541891 0.0023954896 0.363444773 0.65233555 17 47827074 47827204 131 - 1.348 1.403 0.192
ENSG00000159111 E009 0.4911106 0.0161243745 0.867139853   17 47828308 47828500 193 - 0.185 0.161 -0.241
ENSG00000159111 E010 27.3173099 0.0005772085 0.417498889 0.69722282 17 47828501 47828670 170 - 1.424 1.468 0.151
ENSG00000159111 E011 0.7436841 0.0140759710 0.538667096 0.78725300 17 47829139 47829236 98 - 0.185 0.279 0.759
ENSG00000159111 E012 1.1247779 0.0225240492 0.150471214 0.41307614 17 47829237 47829673 437 - 0.185 0.411 1.566
ENSG00000159111 E013 1.9517279 0.1173665001 0.502362683 0.76207870 17 47831311 47831459 149 - 0.531 0.411 -0.604
ENSG00000159111 E014 8.9958373 0.0016704293 0.414358053 0.69461932 17 47831460 47831541 82 - 0.953 1.029 0.279

Help

Please Click HERE to learn more details about the results from DEXseq.