ENSG00000159140

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000436227 ENSG00000159140 No_inf pgKDN_inf SON protein_coding protein_coding 225.4381 292.5252 197.0744 13.36351 5.355647 -0.5697966 8.577525 3.539047 12.876139 2.043468 0.9022529 1.8603163 0.0430250 0.012575 0.065700 0.053125 0.153844792 0.000986265 FALSE TRUE
ENST00000477419 ENSG00000159140 No_inf pgKDN_inf SON protein_coding retained_intron 225.4381 292.5252 197.0744 13.36351 5.355647 -0.5697966 16.123047 24.299848 9.819156 2.010451 1.5205732 -1.3064015 0.0714000 0.083975 0.050375 -0.033600 0.429060453 0.000986265 FALSE FALSE
ENST00000492229 ENSG00000159140 No_inf pgKDN_inf SON protein_coding protein_coding_CDS_not_defined 225.4381 292.5252 197.0744 13.36351 5.355647 -0.5697966 119.203540 177.179427 91.692441 12.200561 4.7310363 -0.9502605 0.5120417 0.603800 0.464425 -0.139375 0.000986265 0.000986265   FALSE
ENST00000704334 ENSG00000159140 No_inf pgKDN_inf SON protein_coding protein_coding 225.4381 292.5252 197.0744 13.36351 5.355647 -0.5697966 27.341961 28.910739 26.553782 2.820738 3.0951468 -0.1226439 0.1259667 0.100150 0.134075 0.033925 0.637214121 0.000986265 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000159140 E001 0.1268540 1.232623e-02 6.783545e-01   21 33543038 33543043 6 + 0.000 0.086 8.745
ENSG00000159140 E002 0.2537079 2.725443e-01 4.006549e-01   21 33543044 33543046 3 + 0.000 0.157 10.984
ENSG00000159140 E003 0.2533610 1.601535e-02 3.332945e-01   21 33543047 33543049 3 + 0.000 0.158 11.835
ENSG00000159140 E004 0.7247103 1.397188e-02 2.724405e-01 5.661481e-01 21 33543050 33543051 2 + 0.321 0.158 -1.326
ENSG00000159140 E005 1.3409793 2.240122e-01 5.307691e-01 7.816323e-01 21 33543052 33543056 5 + 0.422 0.321 -0.589
ENSG00000159140 E006 2.2025461 1.368713e-02 6.297250e-01 8.411826e-01 21 33543057 33543059 3 + 0.540 0.472 -0.326
ENSG00000159140 E007 3.8014751 3.779527e-03 6.428402e-01 8.486464e-01 21 33543060 33543063 4 + 0.709 0.653 -0.233
ENSG00000159140 E008 4.0474406 3.729645e-03 6.248057e-01 8.385803e-01 21 33543064 33543064 1 + 0.731 0.674 -0.239
ENSG00000159140 E009 5.0129206 9.560295e-03 2.470800e-01 5.376610e-01 21 33543065 33543069 5 + 0.847 0.712 -0.538
ENSG00000159140 E010 5.7468817 7.686378e-03 2.363429e-01 5.254313e-01 21 33543070 33543072 3 + 0.895 0.764 -0.511
ENSG00000159140 E011 45.3634249 3.064632e-04 2.678565e-01 5.613565e-01 21 33543073 33543169 97 + 1.630 1.683 0.181
ENSG00000159140 E012 91.5094742 1.766684e-04 2.668829e-02 1.514845e-01 21 33546213 33546379 167 + 1.917 1.991 0.249
ENSG00000159140 E013 0.3727544 1.667365e-02 7.383815e-01   21 33546380 33546752 373 + 0.105 0.158 0.674
ENSG00000159140 E014 0.2454921 1.653217e-02 8.559765e-01   21 33547001 33547039 39 + 0.105 0.086 -0.326
ENSG00000159140 E015 206.7574721 1.072579e-04 9.732935e-01 9.951367e-01 21 33549476 33550100 625 + 2.310 2.314 0.013
ENSG00000159140 E016 40.3678841 2.555440e-03 6.954574e-01 8.756782e-01 21 33550101 33550219 119 + 1.598 1.622 0.081
ENSG00000159140 E017 72.7368292 2.027146e-04 6.134397e-01 8.319382e-01 21 33550220 33550661 442 + 1.851 1.872 0.072
ENSG00000159140 E018 76.8940597 2.566856e-04 5.530803e-02 2.343561e-01 21 33550662 33551289 628 + 1.922 1.859 -0.211
ENSG00000159140 E019 129.3748106 1.290517e-04 5.085803e-03 5.026529e-02 21 33551290 33552247 958 + 2.149 2.079 -0.236
ENSG00000159140 E020 49.4549769 2.919421e-04 1.123198e-02 8.680123e-02 21 33552248 33552559 312 + 1.755 1.650 -0.355
ENSG00000159140 E021 592.0438198 5.414364e-05 1.805128e-19 4.658266e-17 21 33552560 33555048 2489 + 2.822 2.724 -0.328
ENSG00000159140 E022 104.4542964 1.107183e-03 1.423177e-02 1.013838e-01 21 33555049 33555391 343 + 2.060 1.985 -0.252
ENSG00000159140 E023 90.7256551 6.120144e-04 1.464383e-03 2.007116e-02 21 33557156 33557316 161 + 2.013 1.912 -0.338
ENSG00000159140 E024 101.0404695 1.745468e-04 9.544648e-03 7.804443e-02 21 33557546 33559229 1684 + 2.045 1.971 -0.249
ENSG00000159140 E025 56.0350996 2.549821e-04 7.364624e-02 2.762210e-01 21 33559230 33559376 147 + 1.789 1.721 -0.232
ENSG00000159140 E026 24.8045491 5.647814e-04 5.982403e-01 8.238343e-01 21 33559587 33559775 189 + 1.423 1.395 -0.097
ENSG00000159140 E027 50.4043981 3.117963e-03 2.409910e-01 5.303416e-01 21 33559877 33560667 791 + 1.736 1.683 -0.179
ENSG00000159140 E028 20.0893017 6.712238e-04 4.321817e-01 7.096321e-01 21 33567157 33567159 3 + 1.287 1.342 0.192
ENSG00000159140 E029 28.6866431 4.765233e-04 6.057455e-01 8.282279e-01 21 33567160 33567178 19 + 1.449 1.481 0.110
ENSG00000159140 E030 26.4282106 5.158902e-04 8.900487e-01 9.632796e-01 21 33567179 33567184 6 + 1.436 1.432 -0.017
ENSG00000159140 E031 36.3680044 3.830285e-04 6.233236e-01 8.377973e-01 21 33567185 33567267 83 + 1.580 1.559 -0.072
ENSG00000159140 E032 0.4713493 1.593750e-02 2.553739e-02   21 33567268 33567467 200 + 0.321 0.000 -13.885
ENSG00000159140 E033 18.8155597 7.100454e-04 9.478883e-01 9.864242e-01 21 33568971 33569087 117 + 1.293 1.292 -0.005
ENSG00000159140 E034 26.4071460 5.158140e-04 1.120633e-07 6.464194e-06 21 33569088 33569575 488 + 1.213 1.545 1.152
ENSG00000159140 E035 9.6898313 9.298973e-03 2.481015e-02 1.448015e-01 21 33569576 33569775 200 + 0.880 1.107 0.843
ENSG00000159140 E036 6.1111079 7.082624e-02 5.936479e-02 2.444667e-01 21 33569776 33569930 155 + 0.659 0.948 1.142
ENSG00000159140 E037 10.0082835 1.513160e-03 2.160452e-05 6.572014e-04 21 33569931 33570094 164 + 0.753 1.169 1.563
ENSG00000159140 E038 102.7702927 1.684079e-04 2.219229e-30 1.315296e-27 21 33570095 33571734 1640 + 1.759 2.134 1.259
ENSG00000159140 E039 9.4502984 2.540814e-03 7.484260e-03 6.606482e-02 21 33571735 33571750 16 + 0.847 1.107 0.969
ENSG00000159140 E040 11.2080278 2.826792e-02 6.970175e-03 6.294866e-02 21 33571751 33571788 38 + 0.880 1.188 1.133
ENSG00000159140 E041 13.1881660 2.718069e-03 1.096039e-03 1.608976e-02 21 33571789 33571868 80 + 0.965 1.246 1.015
ENSG00000159140 E042 9.4537231 1.573431e-03 3.296376e-03 3.710074e-02 21 33571869 33571903 35 + 0.830 1.115 1.063
ENSG00000159140 E043 26.7451063 1.191693e-02 2.188482e-08 1.459006e-06 21 33571904 33572212 309 + 1.134 1.577 1.543
ENSG00000159140 E044 31.8897285 1.544703e-02 1.749587e-08 1.188441e-06 21 33572213 33572526 314 + 1.199 1.653 1.570
ENSG00000159140 E045 9.4719493 1.618443e-02 4.429930e-03 4.552665e-02 21 33572527 33572550 24 + 0.812 1.122 1.159
ENSG00000159140 E046 14.8539416 9.912871e-04 8.885416e-06 3.083822e-04 21 33572551 33572630 80 + 0.952 1.315 1.307
ENSG00000159140 E047 17.7347142 1.266284e-02 1.172675e-05 3.921083e-04 21 33573025 33573213 189 + 1.002 1.395 1.398
ENSG00000159140 E048 4.2732049 4.002195e-03 2.773992e-04 5.450364e-03 21 33573214 33573307 94 + 0.375 0.866 2.210
ENSG00000159140 E049 0.2457744 1.656637e-02 8.560584e-01   21 33573308 33573455 148 + 0.105 0.086 -0.326
ENSG00000159140 E050 0.0000000       21 33575596 33575667 72 +      
ENSG00000159140 E051 29.7890887 4.845678e-04 6.153413e-01 8.330769e-01 21 33575778 33575893 116 + 1.466 1.497 0.106
ENSG00000159140 E052 15.2107392 4.278217e-03 4.711152e-01 7.386214e-01 21 33576365 33576417 53 + 1.235 1.182 -0.187
ENSG00000159140 E053 443.7967898 1.447833e-04 4.952754e-01 7.565262e-01 21 33576418 33577537 1120 + 2.636 2.649 0.043

Help

Please Click HERE to learn more details about the results from DEXseq.