ENSG00000159202

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000360943 ENSG00000159202 No_inf pgKDN_inf UBE2Z protein_coding protein_coding 51.0615 43.95497 53.17335 1.590437 1.123417 0.2746202 31.796953 21.405494 35.4611736 0.875674 3.8073033 0.7279921 0.61653333 0.489575 0.671950 0.182375 0.36911255 0.02505687 FALSE TRUE
ENST00000504684 ENSG00000159202 No_inf pgKDN_inf UBE2Z protein_coding nonsense_mediated_decay 51.0615 43.95497 53.17335 1.590437 1.123417 0.2746202 6.825807 5.129621 4.0121935 1.962224 4.0121935 -0.3536795 0.13042500 0.115325 0.074300 -0.041025 0.34334349 0.02505687 FALSE TRUE
ENST00000506271 ENSG00000159202 No_inf pgKDN_inf UBE2Z protein_coding retained_intron 51.0615 43.95497 53.17335 1.590437 1.123417 0.2746202 3.768164 8.569559 1.3803325 1.334683 1.1751497 -2.6254736 0.08260833 0.196800 0.026725 -0.170075 0.02505687 0.02505687 FALSE TRUE
ENST00000506498 ENSG00000159202 No_inf pgKDN_inf UBE2Z protein_coding nonsense_mediated_decay 51.0615 43.95497 53.17335 1.590437 1.123417 0.2746202 2.749696 0.000000 8.2490874 0.000000 5.0948120 9.6898386 0.05071667 0.000000 0.152150 0.152150 0.77439535 0.02505687 FALSE TRUE
ENST00000514948 ENSG00000159202 No_inf pgKDN_inf UBE2Z protein_coding protein_coding 51.0615 43.95497 53.17335 1.590437 1.123417 0.2746202 1.964340 4.171171 0.9568224 1.673732 0.9568224 -2.1125842 0.04072500 0.091700 0.017100 -0.074600 0.31641552 0.02505687   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000159202 E001 3.291638 8.525517e-02 7.071898e-01 8.811693e-01 17 48908407 48908472 66 + 0.666 0.591 -0.326
ENSG00000159202 E002 26.469707 6.856630e-04 5.370943e-01 7.861571e-01 17 48908473 48908715 243 + 1.455 1.420 -0.118
ENSG00000159202 E003 19.491101 7.715154e-04 4.170043e-01 6.967477e-01 17 48908716 48908820 105 + 1.336 1.283 -0.183
ENSG00000159202 E004 4.047939 5.656616e-02 4.302195e-01 7.081783e-01 17 48910348 48910689 342 + 0.644 0.760 0.480
ENSG00000159202 E005 1.233029 3.015061e-02 4.036437e-01 6.865381e-01 17 48910690 48910807 118 + 0.281 0.412 0.801
ENSG00000159202 E006 18.714905 8.811923e-04 6.655644e-02 2.599128e-01 17 48910808 48910880 73 + 1.349 1.226 -0.432
ENSG00000159202 E007 17.887810 7.687670e-04 8.091443e-09 5.857770e-07 17 48911179 48912833 1655 + 1.032 1.442 1.448
ENSG00000159202 E008 28.396131 5.094038e-04 4.520557e-03 4.616230e-02 17 48912834 48912965 132 + 1.536 1.379 -0.541
ENSG00000159202 E009 20.029952 1.359370e-02 8.978551e-01 9.662566e-01 17 48912966 48913021 56 + 1.327 1.318 -0.031
ENSG00000159202 E010 6.405909 2.352740e-03 2.314085e-08 1.538938e-06 17 48915720 48916075 356 + 0.450 1.091 2.642
ENSG00000159202 E011 34.036525 4.389756e-04 6.068516e-01 8.288698e-01 17 48916076 48916187 112 + 1.556 1.531 -0.085
ENSG00000159202 E012 22.991098 6.195537e-04 1.612507e-01 4.293770e-01 17 48921160 48921201 42 + 1.418 1.334 -0.293
ENSG00000159202 E013 28.358188 5.557985e-04 1.887868e-01 4.673248e-01 17 48921202 48921272 71 + 1.500 1.429 -0.246
ENSG00000159202 E014 29.953000 4.698042e-04 6.519371e-01 8.534215e-01 17 48922847 48922937 91 + 1.478 1.503 0.087
ENSG00000159202 E015 0.751553 1.406065e-02 6.409355e-02 2.549683e-01 17 48922938 48923097 160 + 0.089 0.365 2.538
ENSG00000159202 E016 502.290219 7.922555e-05 7.869802e-01 9.181963e-01 17 48926964 48929056 2093 + 2.700 2.703 0.011

Help

Please Click HERE to learn more details about the results from DEXseq.