ENSG00000159216

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000344691 ENSG00000159216 No_inf pgKDN_inf RUNX1 protein_coding protein_coding 30.99962 37.56994 29.4148 3.365921 3.86023 -0.3529301 12.670626 12.259418 13.181553 0.2895397 0.3248706 0.1045477 0.43865000 0.333900 0.471775 0.137875 0.528088832 0.004511169 FALSE TRUE
ENST00000437180 ENSG00000159216 No_inf pgKDN_inf RUNX1 protein_coding protein_coding 30.99962 37.56994 29.4148 3.365921 3.86023 -0.3529301 6.289728 13.105473 3.391607 0.3677199 0.7286244 -1.9469812 0.18760000 0.355775 0.116600 -0.239175 0.004511169 0.004511169 FALSE TRUE
ENST00000467577 ENSG00000159216 No_inf pgKDN_inf RUNX1 protein_coding protein_coding_CDS_not_defined 30.99962 37.56994 29.4148 3.365921 3.86023 -0.3529301 5.210129 5.640879 6.327328 3.7337125 3.8061256 0.1653992 0.14108333 0.132500 0.174625 0.042125 1.000000000 0.004511169   FALSE
ENST00000469087 ENSG00000159216 No_inf pgKDN_inf RUNX1 protein_coding retained_intron 30.99962 37.56994 29.4148 3.365921 3.86023 -0.3529301 1.497981 1.093414 1.491560 0.1464449 0.3266444 0.4444877 0.05255833 0.030000 0.055800 0.025800 0.813388635 0.004511169 FALSE FALSE
ENST00000479325 ENSG00000159216 No_inf pgKDN_inf RUNX1 protein_coding protein_coding_CDS_not_defined 30.99962 37.56994 29.4148 3.365921 3.86023 -0.3529301 1.541010 3.175851 1.029385 1.2649891 0.6557753 -1.6159494 0.04639167 0.085375 0.033525 -0.051850 0.654669811 0.004511169   FALSE
MSTRG.18756.16 ENSG00000159216 No_inf pgKDN_inf RUNX1 protein_coding   30.99962 37.56994 29.4148 3.365921 3.86023 -0.3529301 1.146706 0.000000 1.907685 0.0000000 1.1018505 7.5832219 0.03909167 0.000000 0.068875 0.068875 0.426670790 0.004511169   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000159216 E001 530.9822321 0.0017839449 3.319804e-13 4.602836e-11 21 34787801 34791754 3954 - 2.646 2.754 0.360
ENSG00000159216 E002 4.0723811 0.0043183982 9.683364e-01 9.936412e-01 21 34791755 34791785 31 - 0.685 0.704 0.078
ENSG00000159216 E003 59.8000640 0.0003301695 4.164959e-01 6.963729e-01 21 34791786 34792610 825 - 1.775 1.772 -0.008
ENSG00000159216 E004 20.0597955 0.0052642895 2.792513e-01 5.725176e-01 21 34799301 34799462 162 - 1.342 1.293 -0.170
ENSG00000159216 E005 4.4559758 0.0675269470 8.455419e-01 9.450825e-01 21 34821279 34821696 418 - 0.685 0.753 0.279
ENSG00000159216 E006 1.3503829 0.0092398754 6.699733e-01 8.629508e-01 21 34829852 34829970 119 - 0.394 0.346 -0.280
ENSG00000159216 E007 9.8889793 0.0179003512 9.628772e-03 7.841133e-02 21 34832961 34834409 1449 - 1.155 0.919 -0.866
ENSG00000159216 E008 19.9275922 0.0007320689 2.175265e-01 5.039830e-01 21 34834410 34834601 192 - 1.342 1.289 -0.185
ENSG00000159216 E009 0.2536433 0.0160383120 4.365697e-01   21 34856289 34856298 10 - 0.000 0.148 12.222
ENSG00000159216 E010 1.2310504 0.0105974523 9.525174e-01 9.882517e-01 21 34856299 34856447 149 - 0.339 0.346 0.042
ENSG00000159216 E011 15.3675790 0.0010888127 1.941736e-01 4.739571e-01 21 34859474 34859578 105 - 1.244 1.176 -0.242
ENSG00000159216 E012 9.7041446 0.0016408881 2.443326e-01 5.345110e-01 21 34880557 34880605 49 - 1.066 0.988 -0.287
ENSG00000159216 E013 13.1405330 0.0144969034 2.252048e-01 5.128871e-01 21 34880606 34880713 108 - 1.190 1.106 -0.300
ENSG00000159216 E014 15.1745824 0.0009169481 8.365531e-03 7.126624e-02 21 34886843 34887045 203 - 1.293 1.126 -0.590
ENSG00000159216 E015 5.9020713 0.0331514653 4.208290e-01 6.999842e-01 21 34887046 34887096 51 - 0.875 0.797 -0.303
ENSG00000159216 E016 99.1153171 0.0001992274 1.020461e-13 1.516185e-11 21 34887097 34888690 1594 - 2.093 1.908 -0.622
ENSG00000159216 E017 0.3634051 0.0166406211 3.447239e-01   21 34889677 34889790 114 - 0.202 0.080 -1.543
ENSG00000159216 E018 1.8424046 0.0544284418 5.734036e-01 8.088176e-01 21 34892925 34892963 39 - 0.487 0.419 -0.350
ENSG00000159216 E019 5.3235477 0.0026519373 5.756444e-01 8.101152e-01 21 35048842 35048958 117 - 0.735 0.825 0.357
ENSG00000159216 E020 0.1176306 0.0117592829 3.388640e-01   21 35048959 35049080 122 - 0.112 0.000 -12.860
ENSG00000159216 E021 0.0000000       21 35049081 35049167 87 -      
ENSG00000159216 E022 2.2402744 0.0112221804 3.263156e-01 6.187858e-01 21 35049168 35049344 177 - 0.394 0.561 0.835
ENSG00000159216 E023 0.0000000       21 35064716 35064829 114 -      
ENSG00000159216 E024 0.2356421 0.0156709322 1.238913e-01   21 35064936 35065072 137 - 0.202 0.000 -13.759
ENSG00000159216 E025 0.0000000       21 35372507 35372793 287 -      
ENSG00000159216 E026 0.3550369 0.0340978409 4.362549e-02   21 35410123 35410139 17 - 0.276 0.000 -13.954
ENSG00000159216 E027 3.4144547 0.0054440261 5.752320e-02 2.397941e-01 21 35435661 35439071 3411 - 0.758 0.536 -0.958
ENSG00000159216 E028 0.4731135 0.2188278224 3.119124e-02   21 35461961 35462025 65 - 0.339 0.000 -12.033
ENSG00000159216 E029 0.0000000       21 35465184 35465329 146 -      
ENSG00000159216 E030 0.9528918 0.0353147167 5.956123e-03 5.618895e-02 21 35580660 35580929 270 - 0.487 0.080 -3.351
ENSG00000159216 E031 0.0000000       21 35654820 35654875 56 -      
ENSG00000159216 E032 0.2451451 0.0163414579 7.294738e-01   21 35864285 35864467 183 - 0.112 0.080 -0.543
ENSG00000159216 E033 0.4971544 0.0309278582 5.811484e-01   21 35954660 35954825 166 - 0.112 0.206 1.042
ENSG00000159216 E034 0.8881924 0.0400230972 2.294879e-02 1.381892e-01 21 35970075 35970167 93 - 0.000 0.384 13.676
ENSG00000159216 E035 1.1248382 0.1688684704 3.621541e-01 6.513598e-01 21 35981751 35981916 166 - 0.202 0.384 1.265
ENSG00000159216 E036 1.3571793 0.0112192550 8.551103e-01 9.489808e-01 21 35984572 35984830 259 - 0.339 0.384 0.264
ENSG00000159216 E037 0.0000000       21 35988130 35988171 42 -      
ENSG00000159216 E038 0.3731628 0.2480207345 9.565786e-01   21 36004564 36004667 104 - 0.112 0.148 0.457

Help

Please Click HERE to learn more details about the results from DEXseq.