ENSG00000159314

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000376922 ENSG00000159314 No_inf pgKDN_inf ARHGAP27 protein_coding protein_coding 43.99988 59.93179 37.88839 1.971495 1.836105 -0.6614257 0.8483829 0.000000 1.974400 0.0000000 1.9743996 7.632559 0.02214167 0.000000 0.050525 0.050525 0.8215061 0.0231131 FALSE  
ENST00000532038 ENSG00000159314 No_inf pgKDN_inf ARHGAP27 protein_coding protein_coding 43.99988 59.93179 37.88839 1.971495 1.836105 -0.6614257 6.3578452 5.104135 9.862835 3.0321293 1.8384889 0.948974 0.15533333 0.089625 0.257525 0.167900 0.3640588 0.0231131 FALSE  
ENST00000581638 ENSG00000159314 No_inf pgKDN_inf ARHGAP27 protein_coding retained_intron 43.99988 59.93179 37.88839 1.971495 1.836105 -0.6614257 3.6279023 6.574069 1.666804 0.2724542 0.5223631 -1.973266 0.07694167 0.109750 0.042925 -0.066825 0.2463181 0.0231131 TRUE  
ENST00000590026 ENSG00000159314 No_inf pgKDN_inf ARHGAP27 protein_coding retained_intron 43.99988 59.93179 37.88839 1.971495 1.836105 -0.6614257 1.5653521 0.000000 2.700922 0.0000000 1.3066420 8.082640 0.04291667 0.000000 0.070125 0.070125 0.0231131 0.0231131    
ENST00000703659 ENSG00000159314 No_inf pgKDN_inf ARHGAP27 protein_coding retained_intron 43.99988 59.93179 37.88839 1.971495 1.836105 -0.6614257 17.5728605 26.484487 13.178978 2.8332389 1.2088898 -1.006359 0.39170833 0.440550 0.351775 -0.088775 0.6851445 0.0231131 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000159314 E001 0.1265070 0.0123280217 9.105204e-01   17 45393898 45393901 4 - 0.000 0.077 8.607
ENSG00000159314 E002 0.1265070 0.0123280217 9.105204e-01   17 45393902 45393907 6 - 0.000 0.077 10.965
ENSG00000159314 E003 0.3621491 0.0167144131 3.307291e-01   17 45393908 45393908 1 - 0.209 0.077 -1.679
ENSG00000159314 E004 0.3621491 0.0167144131 3.307291e-01   17 45393909 45393909 1 - 0.209 0.077 -1.679
ENSG00000159314 E005 1.5943331 0.2019367318 6.648563e-01 0.860676369 17 45393910 45393913 4 - 0.456 0.372 -0.456
ENSG00000159314 E006 2.2115721 0.0771913893 6.508787e-01 0.853016956 17 45393914 45393919 6 - 0.541 0.468 -0.357
ENSG00000159314 E007 2.2115721 0.0771913893 6.508787e-01 0.853016956 17 45393920 45393938 19 - 0.541 0.468 -0.357
ENSG00000159314 E008 3.5819684 0.0971032745 9.837658e-01 0.998690264 17 45393939 45393944 6 - 0.644 0.651 0.032
ENSG00000159314 E009 236.9128102 0.0032849080 1.068566e-01 0.342500521 17 45393945 45394942 998 - 2.332 2.376 0.146
ENSG00000159314 E010 123.8107569 0.0001741210 1.981164e-01 0.479522867 17 45394943 45395426 484 - 2.057 2.094 0.123
ENSG00000159314 E011 17.2981585 0.0029832093 9.144598e-01 0.973093890 17 45395427 45395454 28 - 1.241 1.251 0.036
ENSG00000159314 E012 12.1010518 0.0048162078 9.282250e-01 0.978727423 17 45395455 45395455 1 - 1.106 1.101 -0.020
ENSG00000159314 E013 40.9401108 0.0015995759 3.978638e-01 0.681911313 17 45395456 45395633 178 - 1.632 1.592 -0.133
ENSG00000159314 E014 29.1138158 0.0005520565 2.194210e-01 0.506083337 17 45395744 45395849 106 - 1.416 1.488 0.248
ENSG00000159314 E015 2.2232223 0.1288091094 8.634861e-01 0.952789576 17 45395850 45395982 133 - 0.501 0.495 -0.027
ENSG00000159314 E016 27.9955601 0.0005369278 1.839527e-01 0.461048528 17 45395983 45396062 80 - 1.395 1.475 0.274
ENSG00000159314 E017 24.2927224 0.0006357533 6.082651e-01 0.829423059 17 45396063 45396117 55 - 1.406 1.377 -0.100
ENSG00000159314 E018 1.2324063 0.0138802104 9.140953e-01 0.972928075 17 45396118 45396163 46 - 0.350 0.335 -0.094
ENSG00000159314 E019 26.0281163 0.0018085468 6.674561e-01 0.861529885 17 45396207 45396284 78 - 1.432 1.408 -0.082
ENSG00000159314 E020 5.8851276 0.0023028745 4.807009e-03 0.048171914 17 45396285 45396486 202 - 0.578 0.922 1.399
ENSG00000159314 E021 17.5068378 0.0010105382 5.407347e-01 0.788634168 17 45396487 45396523 37 - 1.278 1.237 -0.144
ENSG00000159314 E022 19.1621836 0.0007566969 4.708551e-02 0.213162693 17 45396524 45396580 57 - 1.367 1.237 -0.456
ENSG00000159314 E023 9.9290809 0.0014138916 4.508685e-02 0.207660986 17 45396581 45396585 5 - 1.127 0.951 -0.643
ENSG00000159314 E024 19.5670226 0.0040333689 1.666317e-01 0.436968153 17 45396668 45396790 123 - 1.356 1.261 -0.332
ENSG00000159314 E025 1.7401920 0.0077417918 4.488045e-01 0.722755983 17 45396916 45397024 109 - 0.350 0.468 0.643
ENSG00000159314 E026 0.0000000       17 45397025 45397039 15 -      
ENSG00000159314 E027 0.0000000       17 45397040 45397074 35 -      
ENSG00000159314 E028 0.0000000       17 45397075 45397194 120 -      
ENSG00000159314 E029 0.0000000       17 45397205 45397228 24 -      
ENSG00000159314 E030 6.1628526 0.0026566675 5.382809e-05 0.001416869 17 45397514 45397948 435 - 0.456 0.969 2.163
ENSG00000159314 E031 1.5794428 0.0656031362 1.328776e-01 0.387042516 17 45397949 45397964 16 - 0.541 0.294 -1.357
ENSG00000159314 E032 11.1084555 0.0138529539 4.758257e-03 0.047825776 17 45397965 45398047 83 - 1.217 0.951 -0.965
ENSG00000159314 E033 1.8852108 0.0073542870 3.335879e-02 0.173650906 17 45401580 45401668 89 - 0.209 0.546 2.022
ENSG00000159314 E034 12.5684205 0.0292785743 6.981441e-03 0.062997668 17 45402714 45402773 60 - 1.271 0.996 -0.989
ENSG00000159314 E035 10.0592991 0.0059161350 1.055412e-01 0.339873861 17 45402774 45402818 45 - 1.117 0.969 -0.538
ENSG00000159314 E036 14.3618982 0.0020781015 5.155910e-01 0.771583891 17 45403619 45403709 91 - 1.137 1.191 0.193
ENSG00000159314 E037 0.3641952 0.0166879041 3.310294e-01   17 45403710 45404028 319 - 0.209 0.077 -1.679
ENSG00000159314 E038 12.7014071 0.0572237559 6.665582e-01 0.861339079 17 45404029 45404096 68 - 1.156 1.101 -0.199
ENSG00000159314 E039 4.1718062 0.0035022369 3.057566e-01 0.598985781 17 45404097 45404268 172 - 0.775 0.652 -0.509
ENSG00000159314 E040 6.0636225 0.1238085241 9.721147e-01 0.994766022 17 45404269 45404334 66 - 0.818 0.845 0.105
ENSG00000159314 E041 2.0155872 0.0139327700 2.403869e-02 0.141986405 17 45404335 45404444 110 - 0.209 0.569 2.129
ENSG00000159314 E042 8.6546263 0.0026341043 8.417809e-01 0.943210595 17 45404445 45404474 30 - 0.957 0.978 0.080
ENSG00000159314 E043 14.1969773 0.0010828609 8.595715e-01 0.951172118 17 45404475 45404528 54 - 1.174 1.163 -0.041
ENSG00000159314 E044 0.4996734 0.0328672654 6.025969e-01   17 45404529 45404600 72 - 0.117 0.199 0.906
ENSG00000159314 E045 16.0100811 0.0009187528 3.550163e-01 0.644760413 17 45404601 45404681 81 - 1.256 1.191 -0.231
ENSG00000159314 E046 1.9975485 0.0843329919 3.470227e-01 0.637607148 17 45404682 45404923 242 - 0.350 0.521 0.906
ENSG00000159314 E047 17.2377110 0.0049871673 3.052679e-01 0.598598990 17 45404924 45405027 104 - 1.292 1.217 -0.264
ENSG00000159314 E048 14.8140761 0.0008970394 8.500832e-01 0.946889452 17 45405028 45405106 79 - 1.192 1.180 -0.043
ENSG00000159314 E049 21.4720644 0.0006737348 7.178919e-01 0.886507264 17 45405676 45405846 171 - 1.350 1.329 -0.073
ENSG00000159314 E050 23.9315086 0.0068426517 7.210021e-01 0.887637902 17 45405847 45406083 237 - 1.395 1.374 -0.075
ENSG00000159314 E051 3.8385993 0.0868264641 5.594304e-01 0.800501329 17 45407533 45410231 2699 - 0.612 0.704 0.392
ENSG00000159314 E052 6.6096410 0.0482422338 1.238583e-01 0.372736017 17 45410232 45410426 195 - 0.986 0.780 -0.786
ENSG00000159314 E053 0.2373413 0.0157286634 1.177657e-01   17 45425564 45425631 68 - 0.209 0.000 -13.561
ENSG00000159314 E054 0.0000000       17 45429352 45429352 1 -      
ENSG00000159314 E055 0.3707119 0.2391513275 1.000000e+00   17 45429353 45429622 270 - 0.117 0.142 0.322
ENSG00000159314 E056 14.8376895 0.0123858771 7.559986e-01 0.903839994 17 45429623 45430297 675 - 1.165 1.196 0.110
ENSG00000159314 E057 4.4863155 0.0032641776 9.362940e-02 0.318178448 17 45431621 45431752 132 - 0.578 0.794 0.906
ENSG00000159314 E058 4.4509702 0.0095451451 7.939176e-01 0.921396772 17 45432216 45432349 134 - 0.701 0.736 0.145
ENSG00000159314 E059 3.7094302 0.0073011189 8.559365e-01 0.949369732 17 45432752 45433746 995 - 0.644 0.670 0.110
ENSG00000159314 E060 0.6268061 0.0150156718 3.934365e-01 0.678289381 17 45434310 45434421 112 - 0.117 0.249 1.321

Help

Please Click HERE to learn more details about the results from DEXseq.