ENSG00000159322

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000311669 ENSG00000159322 No_inf pgKDN_inf ADPGK protein_coding protein_coding 95.30096 74.83922 105.5728 0.6300029 0.8812659 0.4963151 24.302815 0.000000 32.371589 0.0000000 5.7806606 11.6609581 0.2300250 0.000000 0.305925 0.305925 9.496274e-25 9.496274e-25 FALSE TRUE
ENST00000456471 ENSG00000159322 No_inf pgKDN_inf ADPGK protein_coding protein_coding 95.30096 74.83922 105.5728 0.6300029 0.8812659 0.4963151 30.791815 29.781764 34.575649 1.5636497 5.0286534 0.2152600 0.3299917 0.397975 0.327000 -0.070975 7.160116e-01 9.496274e-25 FALSE TRUE
ENST00000562621 ENSG00000159322 No_inf pgKDN_inf ADPGK protein_coding retained_intron 95.30096 74.83922 105.5728 0.6300029 0.8812659 0.4963151 6.959649 9.224326 5.070528 0.3109558 0.4674552 -0.8620283 0.0779750 0.123300 0.048150 -0.075150 3.155153e-02 9.496274e-25 FALSE TRUE
ENST00000569534 ENSG00000159322 No_inf pgKDN_inf ADPGK protein_coding nonsense_mediated_decay 95.30096 74.83922 105.5728 0.6300029 0.8812659 0.4963151 12.449885 3.096596 16.512711 3.0965957 5.5045186 2.4110440 0.1225333 0.042225 0.156800 0.114575 3.861250e-01 9.496274e-25 FALSE TRUE
ENST00000569693 ENSG00000159322 No_inf pgKDN_inf ADPGK protein_coding nonsense_mediated_decay 95.30096 74.83922 105.5728 0.6300029 0.8812659 0.4963151 11.938338 22.216228 7.874982 4.0480406 5.5072561 -1.4950839 0.1417333 0.295800 0.074725 -0.221075 3.874593e-01 9.496274e-25 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000159322 E001 0.0000000       15 72751294 72751300 7 -      
ENSG00000159322 E002 0.6258335 0.0149263684 1.095122e-01 3.473348e-01 15 72751301 72751366 66 - 0.086 0.321 2.322
ENSG00000159322 E003 2.1042617 0.0069656569 9.886792e-02 3.282048e-01 15 72751367 72751368 2 - 0.364 0.603 1.199
ENSG00000159322 E004 6.4710347 0.0063595454 9.146324e-01 9.730939e-01 15 72751369 72751371 3 - 0.866 0.879 0.051
ENSG00000159322 E005 555.3284451 0.0001920250 2.384824e-03 2.908709e-02 15 72751372 72752429 1058 - 2.757 2.728 -0.098
ENSG00000159322 E006 107.7576303 0.0001738366 6.817316e-01 8.682781e-01 15 72752430 72752634 205 - 2.029 2.043 0.046
ENSG00000159322 E007 129.3606238 0.0013838040 2.867354e-01 5.802297e-01 15 72752635 72752892 258 - 2.127 2.098 -0.097
ENSG00000159322 E008 14.2673339 0.0011700887 9.878475e-01 9.998652e-01 15 72752893 72752895 3 - 1.182 1.183 0.003
ENSG00000159322 E009 56.6087916 0.0002943937 6.742525e-01 8.650083e-01 15 72755556 72755635 80 - 1.751 1.769 0.063
ENSG00000159322 E010 31.7327504 0.0084833345 5.912133e-01 8.191990e-01 15 72755636 72755654 19 - 1.497 1.533 0.125
ENSG00000159322 E011 4.0950180 0.0041997238 1.172945e-02 8.926432e-02 15 72755655 72755981 327 - 0.532 0.847 1.324
ENSG00000159322 E012 2.4032612 0.0067560152 2.910407e-06 1.174046e-04 15 72755982 72756161 180 - 0.086 0.773 4.494
ENSG00000159322 E013 0.7521520 0.0406545998 5.720811e-02 2.390164e-01 15 72756162 72756250 89 - 0.086 0.375 2.647
ENSG00000159322 E014 27.0859258 0.0006333735 6.685102e-01 8.619436e-01 15 72756251 72756260 10 - 1.435 1.461 0.090
ENSG00000159322 E015 86.7525931 0.0001903304 1.162608e-01 3.594800e-01 15 72756261 72756447 187 - 1.964 1.916 -0.162
ENSG00000159322 E016 90.0358819 0.0014826113 8.025598e-30 4.654329e-27 15 72756448 72758610 2163 - 1.727 2.128 1.351
ENSG00000159322 E017 5.2143517 0.0026463880 1.521897e-03 2.071731e-02 15 72760223 72760248 26 - 0.585 0.951 1.482
ENSG00000159322 E018 8.9264182 0.0015025825 1.793558e-04 3.823468e-03 15 72760249 72760394 146 - 0.796 1.151 1.324
ENSG00000159322 E019 1.8263845 0.2364176831 8.097928e-01 9.298226e-01 15 72760395 72760406 12 - 0.439 0.465 0.134
ENSG00000159322 E020 17.9160654 0.0137781713 7.837155e-02 2.866272e-01 15 72760407 72760417 11 - 1.338 1.191 -0.517
ENSG00000159322 E021 20.2367016 0.0053364114 7.906976e-02 2.883595e-01 15 72760418 72760442 25 - 1.380 1.255 -0.435
ENSG00000159322 E022 35.2692534 0.0038498742 1.184605e-02 8.978431e-02 15 72760443 72760527 85 - 1.618 1.478 -0.479
ENSG00000159322 E023 35.2976614 0.0004246281 1.478911e-02 1.040078e-01 15 72771783 72771845 63 - 1.611 1.489 -0.415
ENSG00000159322 E024 52.1532377 0.0002790376 9.510734e-06 3.260979e-04 15 72774872 72775097 226 - 1.800 1.616 -0.626
ENSG00000159322 E025 0.8627316 0.0121855284 5.077629e-01 7.661189e-01 15 72775098 72775114 17 - 0.219 0.321 0.739
ENSG00000159322 E026 0.0000000       15 72783246 72783301 56 -      
ENSG00000159322 E027 0.0000000       15 72783302 72783458 157 -      
ENSG00000159322 E028 0.0000000       15 72783459 72783785 327 -      
ENSG00000159322 E029 0.0000000       15 72785649 72785846 198 -      

Help

Please Click HERE to learn more details about the results from DEXseq.