ENSG00000159377

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000290541 ENSG00000159377 No_inf pgKDN_inf PSMB4 protein_coding protein_coding 324.6715 331.3324 321.5314 2.597258 2.08928 -0.04331794 289.3026 285.4103 294.3974 4.010357 2.013967 0.04472573 0.8914167 0.861525 0.9157 0.054175 0.01498002 0.01498002 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000159377 E001 1.096805 1.089347e-02 5.803308e-01 0.8127758317 1 151399560 151399572 13 + 0.366 0.281 -0.540
ENSG00000159377 E002 7.009990 1.426613e-02 7.460311e-01 0.8995841844 1 151399573 151399578 6 + 0.881 0.917 0.138
ENSG00000159377 E003 26.125484 1.106368e-03 1.037033e-01 0.3365485436 1 151399579 151399586 8 + 1.375 1.471 0.333
ENSG00000159377 E004 29.793110 5.502684e-04 2.056805e-01 0.4890306415 1 151399587 151399589 3 + 1.446 1.515 0.238
ENSG00000159377 E005 169.780661 5.622180e-04 2.504936e-02 0.1455986692 1 151399590 151399727 138 + 2.259 2.205 -0.181
ENSG00000159377 E006 342.569685 7.963854e-05 8.281971e-01 0.9377449464 1 151399981 151400173 193 + 2.535 2.532 -0.011
ENSG00000159377 E007 135.242385 1.219428e-04 6.685259e-01 0.8619435827 1 151400174 151400185 12 + 2.126 2.136 0.036
ENSG00000159377 E008 116.018043 1.677354e-04 9.912479e-01 1.0000000000 1 151400186 151400187 2 + 2.066 2.065 -0.001
ENSG00000159377 E009 2.552758 5.748764e-03 1.549097e-01 0.4205205141 1 151400188 151400441 254 + 0.647 0.450 -0.919
ENSG00000159377 E010 380.836088 1.070480e-03 5.573512e-01 0.7993666303 1 151400442 151400588 147 + 2.585 2.574 -0.035
ENSG00000159377 E011 24.722010 1.175864e-02 4.810694e-01 0.7462126384 1 151400589 151400763 175 + 1.380 1.429 0.172
ENSG00000159377 E012 247.218954 1.529588e-04 6.132032e-01 0.8318103924 1 151400764 151400845 82 + 2.397 2.388 -0.032
ENSG00000159377 E013 11.858616 1.189421e-03 8.738194e-02 0.3063878170 1 151400846 151400900 55 + 1.021 1.165 0.519
ENSG00000159377 E014 42.107679 4.294484e-04 3.118813e-05 0.0008931076 1 151400901 151401238 338 + 1.511 1.709 0.675
ENSG00000159377 E015 253.997250 1.740175e-03 5.997014e-01 0.8245853137 1 151401239 151401355 117 + 2.397 2.409 0.040
ENSG00000159377 E016 12.972174 2.662191e-02 2.660108e-01 0.5594578764 1 151401356 151401541 186 + 1.073 1.191 0.424
ENSG00000159377 E017 163.434811 1.167306e-04 3.308830e-01 0.6231525203 1 151401542 151401630 89 + 2.226 2.203 -0.075
ENSG00000159377 E018 3.202038 4.302393e-03 6.916688e-01 0.8736743933 1 151401631 151401816 186 + 0.592 0.644 0.229
ENSG00000159377 E019 85.788369 1.839636e-04 6.530286e-01 0.8540774028 1 151401817 151401937 121 + 1.944 1.929 -0.049

Help

Please Click HERE to learn more details about the results from DEXseq.