ENSG00000159692

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000290921 ENSG00000159692 No_inf pgKDN_inf CTBP1 protein_coding protein_coding 72.06359 92.06729 59.69171 3.374706 2.015206 -0.6250732 7.441543 8.894415 7.481295 2.8473245 2.5074900 -0.2493056 0.10434167 0.098875 0.123400 0.024525 0.99584166 0.01287246 FALSE  
ENST00000382952 ENSG00000159692 No_inf pgKDN_inf CTBP1 protein_coding protein_coding 72.06359 92.06729 59.69171 3.374706 2.015206 -0.6250732 26.935737 28.413903 24.743041 1.6056884 3.1304634 -0.1994989 0.38630000 0.308800 0.420475 0.111675 0.57142682 0.01287246 FALSE  
ENST00000514596 ENSG00000159692 No_inf pgKDN_inf CTBP1 protein_coding retained_intron 72.06359 92.06729 59.69171 3.374706 2.015206 -0.6250732 3.633677 8.880199 0.000000 2.9827131 0.0000000 -9.7960719 0.04129167 0.093425 0.000000 -0.093425 0.01543142 0.01287246 FALSE  
MSTRG.21426.1 ENSG00000159692 No_inf pgKDN_inf CTBP1 protein_coding   72.06359 92.06729 59.69171 3.374706 2.015206 -0.6250732 3.692416 7.197137 1.140324 0.3140962 0.1718073 -2.6473855 0.04680000 0.078225 0.019075 -0.059150 0.01287246 0.01287246 FALSE  
MSTRG.21426.2 ENSG00000159692 No_inf pgKDN_inf CTBP1 protein_coding   72.06359 92.06729 59.69171 3.374706 2.015206 -0.6250732 17.242792 21.197729 16.314990 2.0801648 6.2773385 -0.3775080 0.24134167 0.230450 0.270625 0.040175 1.00000000 0.01287246 FALSE  
MSTRG.21426.6 ENSG00000159692 No_inf pgKDN_inf CTBP1 protein_coding   72.06359 92.06729 59.69171 3.374706 2.015206 -0.6250732 2.569065 0.000000 4.369762 0.0000000 4.3697622 8.7747087 0.04139167 0.000000 0.072275 0.072275 0.82503655 0.01287246 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000159692 E001 0.3644125 0.2609527810 3.239801e-01   4 1211442 1211444 3 - 0.224 0.071 -1.932
ENSG00000159692 E002 0.4814165 0.0383915200 1.064709e-01   4 1211445 1211446 2 - 0.304 0.071 -2.516
ENSG00000159692 E003 0.9812463 0.1013685923 3.976316e-01 6.818384e-01 4 1211447 1211447 1 - 0.371 0.233 -0.931
ENSG00000159692 E004 1.2271467 0.0773574791 3.521096e-01 6.421649e-01 4 1211448 1211449 2 - 0.430 0.276 -0.931
ENSG00000159692 E005 5.6609723 0.1541186207 4.793629e-01 7.451352e-01 4 1211450 1211455 6 - 0.890 0.749 -0.551
ENSG00000159692 E006 53.7428113 0.0010789502 9.068985e-03 7.544757e-02 4 1211456 1211684 229 - 1.784 1.671 -0.381
ENSG00000159692 E007 77.9118032 0.0011559382 1.610184e-03 2.159752e-02 4 1211685 1211848 164 - 1.944 1.829 -0.386
ENSG00000159692 E008 54.3790140 0.0003025520 2.480657e-01 5.389179e-01 4 1211849 1211913 65 - 1.749 1.700 -0.166
ENSG00000159692 E009 54.3585048 0.0017820891 1.445188e-01 4.047299e-01 4 1211914 1212177 264 - 1.759 1.694 -0.222
ENSG00000159692 E010 0.0000000       4 1212178 1212179 2 -      
ENSG00000159692 E011 0.0000000       4 1212180 1212181 2 -      
ENSG00000159692 E012 0.0000000       4 1212182 1212274 93 -      
ENSG00000159692 E013 0.0000000       4 1212275 1212423 149 -      
ENSG00000159692 E014 0.0000000       4 1212424 1212426 3 -      
ENSG00000159692 E015 42.3491919 0.0024893427 1.169723e-01 3.609970e-01 4 1212913 1213030 118 - 1.662 1.582 -0.272
ENSG00000159692 E016 0.5070043 0.0158462174 1.700836e-01 4.421837e-01 4 1213031 1213050 20 - 0.000 0.233 11.345
ENSG00000159692 E017 66.2241773 0.0002209868 4.380609e-03 4.519901e-02 4 1213478 1213605 128 - 1.869 1.763 -0.359
ENSG00000159692 E018 2.8529816 0.0097828503 6.872667e-01 8.709670e-01 4 1213606 1213754 149 - 0.527 0.584 0.262
ENSG00000159692 E019 3.3612152 0.0054792566 3.468724e-01 6.375265e-01 4 1213991 1214190 200 - 0.527 0.658 0.584
ENSG00000159692 E020 3.3808844 0.0042425712 6.924549e-02 2.659086e-01 4 1214191 1214342 152 - 0.430 0.690 1.207
ENSG00000159692 E021 46.6281244 0.0004290084 3.275719e-02 1.716297e-01 4 1214343 1214420 78 - 1.713 1.617 -0.327
ENSG00000159692 E022 19.5832112 0.0007030772 4.490055e-02 2.071217e-01 4 1214421 1214473 53 - 1.374 1.238 -0.473
ENSG00000159692 E023 0.0000000       4 1215991 1216085 95 -      
ENSG00000159692 E024 0.0000000       4 1216086 1216174 89 -      
ENSG00000159692 E025 0.0000000       4 1216175 1216205 31 -      
ENSG00000159692 E026 0.0000000       4 1216206 1216407 202 -      
ENSG00000159692 E027 1.3723190 0.0097075923 6.138190e-01 8.321010e-01 4 1221458 1221839 382 - 0.304 0.384 0.484
ENSG00000159692 E028 0.4996734 0.0292628208 7.236804e-01   4 1223420 1223512 93 - 0.126 0.185 0.654
ENSG00000159692 E029 0.2451451 0.0166597452 6.160869e-01   4 1225351 1225359 9 - 0.126 0.071 -0.931
ENSG00000159692 E030 22.6244156 0.0007627188 4.450795e-01 7.195325e-01 4 1225360 1225437 78 - 1.380 1.330 -0.173
ENSG00000159692 E031 55.7705499 0.0007710430 1.374056e-02 9.879791e-02 4 1225438 1225566 129 - 1.794 1.691 -0.348
ENSG00000159692 E032 58.4310973 0.0002602062 2.837973e-03 3.311623e-02 4 1228199 1228343 145 - 1.823 1.704 -0.401
ENSG00000159692 E033 0.3715287 0.2123071560 1.000000e+00   4 1231108 1231144 37 - 0.126 0.132 0.070
ENSG00000159692 E034 1.5052167 0.0086487897 1.724712e-01 4.452665e-01 4 1232888 1233224 337 - 0.224 0.443 1.391
ENSG00000159692 E035 5.2319129 0.0027054917 2.536867e-01 5.452217e-01 4 1234687 1235752 1066 - 0.674 0.813 0.564
ENSG00000159692 E036 2.1518817 0.0177567948 5.807562e-03 5.513555e-02 4 1235753 1236316 564 - 0.126 0.584 3.069
ENSG00000159692 E037 1.8952478 0.0619531878 1.845313e-02 1.201994e-01 4 1236317 1237102 786 - 0.126 0.542 2.876
ENSG00000159692 E038 0.1271363 0.0124153688 1.000000e+00   4 1237103 1237264 162 - 0.000 0.071 9.452
ENSG00000159692 E039 0.1268540 0.0123568894 1.000000e+00   4 1237265 1237474 210 - 0.000 0.071 9.453
ENSG00000159692 E040 1.3794322 0.0098939127 2.363207e-01 5.254313e-01 4 1237475 1238182 708 - 0.224 0.414 1.239
ENSG00000159692 E041 67.7102207 0.0043993113 1.243095e-05 4.120780e-04 4 1238183 1238337 155 - 1.930 1.737 -0.652
ENSG00000159692 E042 60.3679092 0.0002841839 3.867921e-02 1.902530e-01 4 1241325 1241515 191 - 1.814 1.732 -0.277
ENSG00000159692 E043 13.6407713 0.0069502520 8.699532e-01 9.552120e-01 4 1241516 1241519 4 - 1.130 1.144 0.050
ENSG00000159692 E044 3.2616159 0.0046583474 3.033438e-02 1.638676e-01 4 1241520 1241650 131 - 0.371 0.690 1.529
ENSG00000159692 E045 38.3804484 0.0087165810 1.625342e-08 1.113865e-06 4 1241651 1242289 639 - 1.269 1.663 1.357
ENSG00000159692 E046 121.2742632 0.0001784351 3.055927e-52 5.683392e-49 4 1242290 1246230 3941 - 1.662 2.172 1.714
ENSG00000159692 E047 34.8492134 0.0003861989 7.138541e-17 1.447406e-14 4 1246231 1247760 1530 - 1.108 1.642 1.859
ENSG00000159692 E048 5.1427328 0.0028671990 1.390484e-02 9.955446e-02 4 1247861 1248207 347 - 0.527 0.847 1.349
ENSG00000159692 E049 0.7525615 0.0141317345 3.448776e-01 6.359596e-01 4 1248208 1248242 35 - 0.126 0.276 1.391
ENSG00000159692 E050 0.7457302 0.0140385546 9.546749e-01 9.889887e-01 4 1248661 1248915 255 - 0.224 0.233 0.069
ENSG00000159692 E051 23.2562593 0.0202211644 4.291001e-04 7.734988e-03 4 1248916 1249137 222 - 1.533 1.238 -1.022
ENSG00000159692 E052 0.0000000       4 1249649 1250159 511 -      
ENSG00000159692 E053 0.0000000       4 1250160 1250333 174 -      

Help

Please Click HERE to learn more details about the results from DEXseq.