ENSG00000160007

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000596593 ENSG00000160007 No_inf pgKDN_inf ARHGAP35 protein_coding protein_coding_CDS_not_defined 13.87063 14.37059 12.65498 1.510764 0.3806133 -0.1832779 1.214185 2.036099 0.000000 1.4956395 0.0000000 -7.6767324 0.07384167 0.116275 0.000000 -0.116275 0.496634511 0.004542376   FALSE
ENST00000599284 ENSG00000160007 No_inf pgKDN_inf ARHGAP35 protein_coding retained_intron 13.87063 14.37059 12.65498 1.510764 0.3806133 -0.1832779 3.556877 5.273520 1.623524 0.4152255 0.6054749 -1.6935114 0.25191667 0.372275 0.124675 -0.247600 0.211719595 0.004542376 FALSE FALSE
ENST00000672722 ENSG00000160007 No_inf pgKDN_inf ARHGAP35 protein_coding protein_coding 13.87063 14.37059 12.65498 1.510764 0.3806133 -0.1832779 8.652082 6.395013 10.755825 0.2216944 0.2723849 0.7491856 0.64162500 0.462100 0.853450 0.391350 0.004542376 0.004542376 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000160007 E001 2.2892073 9.730033e-03 5.948811e-02 2.446619e-01 19 46860997 46861209 213 + 0.631 0.358 -1.354
ENSG00000160007 E002 77.5130728 2.234840e-04 1.984035e-06 8.439034e-05 19 46918488 46920782 2295 + 1.964 1.812 -0.512
ENSG00000160007 E003 88.9349627 2.008950e-04 1.008904e-04 2.391943e-03 19 46920783 46922356 1574 + 2.007 1.893 -0.383
ENSG00000160007 E004 9.3770508 1.741423e-03 3.846019e-01 6.707497e-01 19 46937264 46937319 56 + 1.053 0.976 -0.283
ENSG00000160007 E005 12.4776216 2.280806e-03 9.671501e-01 9.933727e-01 19 46937320 46937408 89 + 1.127 1.132 0.019
ENSG00000160007 E006 11.0679172 1.105482e-02 6.833112e-05 1.720559e-03 19 46946557 46952263 5707 + 0.850 1.234 1.408
ENSG00000160007 E007 10.3959176 1.078800e-02 8.921966e-01 9.641748e-01 19 46987989 46988066 78 + 1.062 1.051 -0.038
ENSG00000160007 E008 0.2459655 1.649135e-02 9.462141e-01   19 46988067 46989543 1477 + 0.091 0.099 0.132
ENSG00000160007 E009 7.4779340 1.823614e-03 6.434319e-01 8.488184e-01 19 46989544 46989583 40 + 0.904 0.951 0.179
ENSG00000160007 E010 11.6228708 1.224325e-03 9.095802e-01 9.712891e-01 19 46989584 46989675 92 + 1.095 1.107 0.041
ENSG00000160007 E011 0.5082940 2.181034e-01 6.586547e-02 2.585118e-01 19 46997497 46997750 254 + 0.000 0.306 11.542
ENSG00000160007 E012 0.1186381 1.184526e-02 5.862666e-01   19 46999085 46999097 13 + 0.091 0.000 -11.033
ENSG00000160007 E013 0.2438580 1.640159e-02 9.463670e-01   19 46999098 46999144 47 + 0.091 0.099 0.132
ENSG00000160007 E014 0.4890031 1.586136e-02 9.315014e-01   19 46999145 46999303 159 + 0.167 0.180 0.132
ENSG00000160007 E015 14.3793529 9.436838e-04 3.145531e-01 6.075675e-01 19 46999304 46999409 106 + 1.222 1.148 -0.262
ENSG00000160007 E016 0.2533610 1.606078e-02 2.140555e-01   19 46999410 46999815 406 + 0.000 0.180 11.200
ENSG00000160007 E017 306.2734498 9.752416e-05 3.837845e-08 2.443806e-06 19 47000331 47005077 4747 + 2.453 2.520 0.222

Help

Please Click HERE to learn more details about the results from DEXseq.