ENSG00000160209

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000291565 ENSG00000160209 No_inf pgKDN_inf PDXK protein_coding protein_coding 89.96965 40.7718 92.74983 1.944104 6.594308 1.185575 11.168330 8.572914 10.848932 0.2988074 1.925870 0.3393427907 0.14454167 0.212300 0.117525 -0.094775 3.237666e-01 2.956036e-15 FALSE TRUE
ENST00000343528 ENSG00000160209 No_inf pgKDN_inf PDXK protein_coding protein_coding_CDS_not_defined 89.96965 40.7718 92.74983 1.944104 6.594308 1.185575 11.197965 0.000000 16.335452 0.0000000 1.741590 10.6746735841 0.10163333 0.000000 0.177550 0.177550 2.956036e-15 2.956036e-15 FALSE TRUE
ENST00000398085 ENSG00000160209 No_inf pgKDN_inf PDXK protein_coding protein_coding_CDS_not_defined 89.96965 40.7718 92.74983 1.944104 6.594308 1.185575 10.435089 0.000000 11.988162 0.0000000 2.890124 10.2285977549 0.09108333 0.000000 0.132100 0.132100 6.919165e-08 2.956036e-15 FALSE FALSE
ENST00000470029 ENSG00000160209 No_inf pgKDN_inf PDXK protein_coding protein_coding_CDS_not_defined 89.96965 40.7718 92.74983 1.944104 6.594308 1.185575 3.811921 3.599356 1.131988 1.3493255 1.131988 -1.6601936434 0.04978333 0.089475 0.010675 -0.078800 2.162966e-01 2.956036e-15 FALSE TRUE
ENST00000481512 ENSG00000160209 No_inf pgKDN_inf PDXK protein_coding protein_coding_CDS_not_defined 89.96965 40.7718 92.74983 1.944104 6.594308 1.185575 14.492664 8.044033 28.254545 5.1601791 11.009536 1.8112102042 0.18369167 0.196450 0.305775 0.109325 8.352413e-01 2.956036e-15 FALSE FALSE
ENST00000490666 ENSG00000160209 No_inf pgKDN_inf PDXK protein_coding protein_coding_CDS_not_defined 89.96965 40.7718 92.74983 1.944104 6.594308 1.185575 25.789953 11.545919 11.540064 4.5814288 11.540064 -0.0007312031 0.26603333 0.280750 0.116400 -0.164350 3.333959e-01 2.956036e-15 FALSE FALSE
MSTRG.18867.5 ENSG00000160209 No_inf pgKDN_inf PDXK protein_coding   89.96965 40.7718 92.74983 1.944104 6.594308 1.185575 2.819487 3.943331 3.656503 0.1514277 1.366753 -0.1086640071 0.04808333 0.097725 0.039925 -0.057800 5.250393e-01 2.956036e-15 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000160209 E001 0.0000000       21 43719094 43719096 3 +      
ENSG00000160209 E002 0.7171887 1.455067e-02 2.752463e-01 5.687572e-01 21 43719097 43719128 32 + 0.290 0.119 -1.584
ENSG00000160209 E003 6.6660354 6.962128e-02 9.010963e-01 9.680599e-01 21 43719129 43719175 47 + 0.883 0.865 -0.070
ENSG00000160209 E004 6.7928894 7.852702e-02 9.904944e-01 1.000000e+00 21 43719176 43719176 1 + 0.883 0.883 0.001
ENSG00000160209 E005 14.9626990 2.072173e-02 1.438268e-01 4.038067e-01 21 43719177 43719222 46 + 1.243 1.104 -0.496
ENSG00000160209 E006 31.6123209 4.852094e-04 8.863649e-03 7.417410e-02 21 43719223 43719381 159 + 1.555 1.409 -0.501
ENSG00000160209 E007 0.0000000       21 43721692 43721906 215 +      
ENSG00000160209 E008 1.0080587 1.181235e-02 3.657707e-03 3.991801e-02 21 43723497 43723893 397 + 0.075 0.507 3.545
ENSG00000160209 E009 0.0000000       21 43728730 43728899 170 +      
ENSG00000160209 E010 0.0000000       21 43728900 43728912 13 +      
ENSG00000160209 E011 0.0000000       21 43728913 43728916 4 +      
ENSG00000160209 E012 0.1186381 1.178578e-02 1.000000e+00   21 43728917 43729010 94 + 0.075 0.000 -9.240
ENSG00000160209 E013 3.1778049 6.527496e-03 3.743805e-01 6.620302e-01 21 43732139 43732442 304 + 0.563 0.681 0.515
ENSG00000160209 E014 1.3678184 9.610957e-03 1.897341e-02 1.226404e-01 21 43732443 43732647 205 + 0.196 0.548 2.153
ENSG00000160209 E015 0.3622142 1.651099e-02 1.000000e+00   21 43733671 43733706 36 + 0.140 0.119 -0.262
ENSG00000160209 E016 0.0000000       21 43734062 43734068 7 +      
ENSG00000160209 E017 23.7608265 6.066054e-04 1.203025e-02 9.064540e-02 21 43734069 43734123 55 + 1.440 1.279 -0.559
ENSG00000160209 E018 3.0104917 1.911784e-02 1.076830e-05 3.648101e-04 21 43736954 43737580 627 + 0.245 0.865 3.060
ENSG00000160209 E019 4.9614019 3.144080e-02 8.515364e-04 1.323919e-02 21 43737581 43738861 1281 + 0.540 0.979 1.792
ENSG00000160209 E020 0.0000000       21 43741016 43741040 25 +      
ENSG00000160209 E021 0.0000000       21 43741420 43741464 45 +      
ENSG00000160209 E022 0.0000000       21 43741465 43741475 11 +      
ENSG00000160209 E023 0.0000000       21 43741476 43741572 97 +      
ENSG00000160209 E024 0.0000000       21 43741573 43741576 4 +      
ENSG00000160209 E025 0.0000000       21 43741577 43741666 90 +      
ENSG00000160209 E026 35.7923584 1.775279e-03 1.078283e-01 3.442762e-01 21 43741667 43741771 105 + 1.588 1.500 -0.299
ENSG00000160209 E027 0.0000000       21 43743669 43743723 55 +      
ENSG00000160209 E028 41.9119419 3.891573e-04 9.348621e-03 7.696375e-02 21 43743724 43743807 84 + 1.667 1.542 -0.428
ENSG00000160209 E029 2.1224187 7.363568e-03 1.217407e-03 1.741173e-02 21 43744471 43744650 180 + 0.245 0.708 2.438
ENSG00000160209 E030 4.3847829 3.930121e-03 3.974644e-01 6.816383e-01 21 43745703 43746078 376 + 0.680 0.782 0.416
ENSG00000160209 E031 35.6647833 2.342021e-03 5.665349e-02 2.375456e-01 21 43746079 43746125 47 + 1.592 1.487 -0.359
ENSG00000160209 E032 0.3532727 1.571733e-02 2.467520e-01   21 43747116 43747186 71 + 0.196 0.000 -10.733
ENSG00000160209 E033 40.6530737 5.432514e-04 9.189191e-02 3.148328e-01 21 43748995 43749080 86 + 1.640 1.557 -0.282
ENSG00000160209 E034 33.3612100 4.426172e-04 7.023426e-02 2.681329e-01 21 43750500 43750545 46 + 1.562 1.464 -0.334
ENSG00000160209 E035 56.9086225 2.740910e-04 9.882296e-03 7.964611e-02 21 43752518 43752629 112 + 1.791 1.685 -0.360
ENSG00000160209 E036 61.2718723 2.767801e-04 3.187345e-07 1.660930e-05 21 43753583 43753719 137 + 1.854 1.646 -0.704
ENSG00000160209 E037 0.3533378 1.574939e-02 2.466808e-01   21 43755477 43755697 221 + 0.196 0.000 -10.733
ENSG00000160209 E038 39.7901460 8.121957e-03 1.326803e-04 2.990380e-03 21 43755698 43755764 67 + 1.680 1.440 -0.818
ENSG00000160209 E039 53.2980319 3.262765e-04 2.602606e-02 1.491768e-01 21 43755951 43756129 179 + 1.760 1.665 -0.322
ENSG00000160209 E040 47.5475217 2.980042e-04 8.559259e-02 3.028002e-01 21 43756130 43756782 653 + 1.705 1.627 -0.262
ENSG00000160209 E041 410.1553091 9.310628e-05 2.682840e-30 1.572786e-27 21 43756783 43762307 5525 + 2.547 2.679 0.440

Help

Please Click HERE to learn more details about the results from DEXseq.