ENSG00000160219

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000369575 ENSG00000160219 No_inf pgKDN_inf GAB3 protein_coding protein_coding 2.795726 3.201204 2.542535 0.09455161 0.2832031 -0.3311837 0.7674881 0.8921934 1.0480567 0.5221247 0.6104733 0.2299082 0.2970333 0.275100 0.500000 0.224900 0.966740238 0.003931737 FALSE TRUE
ENST00000424127 ENSG00000160219 No_inf pgKDN_inf GAB3 protein_coding protein_coding 2.795726 3.201204 2.542535 0.09455161 0.2832031 -0.3311837 0.8326092 0.8504262 0.7910012 0.4982705 0.4774081 -0.1032472 0.3053167 0.273225 0.269925 -0.003300 1.000000000 0.003931737 FALSE TRUE
ENST00000454973 ENSG00000160219 No_inf pgKDN_inf GAB3 protein_coding protein_coding 2.795726 3.201204 2.542535 0.09455161 0.2832031 -0.3311837 0.1437192 0.0000000 0.4311575 0.0000000 0.2489358 5.4632219 0.0483000 0.000000 0.144900 0.144900 0.424905900 0.003931737 FALSE FALSE
ENST00000496390 ENSG00000160219 No_inf pgKDN_inf GAB3 protein_coding protein_coding_CDS_not_defined 2.795726 3.201204 2.542535 0.09455161 0.2832031 -0.3311837 0.3817302 0.2350032 0.2723196 0.2350032 0.2723196 0.2045288 0.1326917 0.069700 0.085175 0.015475 0.986345240 0.003931737 FALSE TRUE
MSTRG.30588.1 ENSG00000160219 No_inf pgKDN_inf GAB3 protein_coding   2.795726 3.201204 2.542535 0.09455161 0.2832031 -0.3311837 0.6701796 1.2235814 0.0000000 0.1730199 0.0000000 -6.9467091 0.2166667 0.382000 0.000000 -0.382000 0.003931737 0.003931737 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000160219 E001 0.2537079 0.1938450058 0.412019089   X 154675249 154675252 4 - 0.000 0.150 10.032
ENSG00000160219 E002 16.0273355 0.0009069614 0.001297454 0.01830897 X 154675253 154676168 916 - 1.092 1.291 0.708
ENSG00000160219 E003 12.1942145 0.0270547224 0.851914629 0.94767683 X 154676169 154676918 750 - 1.112 1.112 0.001
ENSG00000160219 E004 15.1440430 0.0016650951 0.847291588 0.94585057 X 154676919 154678174 1256 - 1.215 1.188 -0.098
ENSG00000160219 E005 1.3413502 0.0099693308 0.416385350 0.69625528 X 154678175 154678289 115 - 0.439 0.307 -0.762
ENSG00000160219 E006 0.5889799 0.0148933984 0.007843449 0.06822297 X 154678290 154678294 5 - 0.390 0.000 -14.930
ENSG00000160219 E007 0.2357071 0.0160657914 0.152695671   X 154678978 154679339 362 - 0.199 0.000 -13.907
ENSG00000160219 E008 2.0856363 0.0431142604 0.702843668 0.87914955 X 154680132 154680248 117 - 0.522 0.455 -0.329
ENSG00000160219 E009 0.9973919 0.0166702864 0.312167458 0.60556739 X 154695917 154696019 103 - 0.199 0.349 1.086
ENSG00000160219 E010 0.0000000       X 154696020 154696092 73 -      
ENSG00000160219 E011 2.1058979 0.0074867081 0.553891176 0.79685787 X 154697132 154697213 82 - 0.439 0.514 0.376
ENSG00000160219 E012 2.9037413 0.0273400130 0.021966444 0.13452234 X 154699294 154699513 220 - 0.752 0.423 -1.499
ENSG00000160219 E013 0.7354719 0.0150108231 0.706585063 0.88098229 X 154700004 154700059 56 - 0.273 0.209 -0.499
ENSG00000160219 E014 0.0000000       X 154706156 154706189 34 -      
ENSG00000160219 E015 4.0983206 0.0047877829 0.147686539 0.40910764 X 154712229 154712701 473 - 0.592 0.759 0.703
ENSG00000160219 E016 2.6781032 0.0058898045 0.112288866 0.35220859 X 154713207 154713423 217 - 0.680 0.455 -1.029
ENSG00000160219 E017 0.2458395 0.0165106457 0.810317655   X 154713424 154713426 3 - 0.111 0.081 -0.499
ENSG00000160219 E018 2.1718485 0.0074781845 0.010163423 0.08113588 X 154716026 154716329 304 - 0.680 0.307 -1.877
ENSG00000160219 E019 0.3638483 0.0172920453 0.409026103   X 154750954 154751077 124 - 0.199 0.081 -1.499
ENSG00000160219 E020 0.1186381 0.0120768659 0.391683852   X 154751492 154751583 92 - 0.111 0.000 -13.061

Help

Please Click HERE to learn more details about the results from DEXseq.