ENSG00000160310

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000355680 ENSG00000160310 No_inf pgKDN_inf PRMT2 protein_coding protein_coding 45.19944 31.86679 48.98502 1.537652 4.20579 0.6201286 4.7965390 1.8441110 6.9603024 1.1188034 0.5470378 1.91049364 0.1002917 0.053700 0.145450 0.091750 0.401296413 0.001436772 FALSE  
ENST00000397628 ENSG00000160310 No_inf pgKDN_inf PRMT2 protein_coding protein_coding 45.19944 31.86679 48.98502 1.537652 4.20579 0.6201286 12.9710995 6.5384754 12.8067214 1.0178100 3.0343079 0.96879630 0.2728583 0.202025 0.259525 0.057500 0.851122853 0.001436772 FALSE  
ENST00000397638 ENSG00000160310 No_inf pgKDN_inf PRMT2 protein_coding protein_coding 45.19944 31.86679 48.98502 1.537652 4.20579 0.6201286 2.9486284 2.2881202 2.7811189 1.3382185 1.6806407 0.28038930 0.0694500 0.078425 0.060775 -0.017650 0.994285431 0.001436772 FALSE  
ENST00000455177 ENSG00000160310 No_inf pgKDN_inf PRMT2 protein_coding protein_coding 45.19944 31.86679 48.98502 1.537652 4.20579 0.6201286 4.3571373 0.7243646 7.5308021 0.7243646 3.9486933 3.36014948 0.0834750 0.020725 0.141450 0.120725 0.094514968 0.001436772 FALSE  
ENST00000458387 ENSG00000160310 No_inf pgKDN_inf PRMT2 protein_coding protein_coding 45.19944 31.86679 48.98502 1.537652 4.20579 0.6201286 0.7507413 2.1139010 0.1383229 0.2929266 0.1383229 -3.83990328 0.0231500 0.066500 0.002950 -0.063550 0.001436772 0.001436772 FALSE  
ENST00000481861 ENSG00000160310 No_inf pgKDN_inf PRMT2 protein_coding retained_intron 45.19944 31.86679 48.98502 1.537652 4.20579 0.6201286 13.0467574 12.2796469 12.9247984 0.4699051 0.7344834 0.07381411 0.3037000 0.386150 0.270275 -0.115875 0.419584166 0.001436772 FALSE  
ENST00000486520 ENSG00000160310 No_inf pgKDN_inf PRMT2 protein_coding retained_intron 45.19944 31.86679 48.98502 1.537652 4.20579 0.6201286 2.1206039 2.7482018 1.5143650 0.2406624 0.1196442 -0.85551961 0.0518750 0.086200 0.031000 -0.055200 0.177414654 0.001436772 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000160310 E001 0.1271363 0.0122681679 4.993515e-01   21 46635595 46635614 20 + 0.000 0.098 9.594
ENSG00000160310 E002 0.3804973 0.0158562403 8.932773e-02   21 46635615 46635641 27 + 0.000 0.246 13.271
ENSG00000160310 E003 0.6165488 0.0194036046 5.974375e-01 8.233137e-01 21 46635642 46635649 8 + 0.168 0.246 0.695
ENSG00000160310 E004 0.7430558 0.0357438859 3.706345e-01 6.589249e-01 21 46635650 46635652 3 + 0.168 0.305 1.110
ENSG00000160310 E005 1.4796277 0.0101601089 4.833901e-01 7.479678e-01 21 46635653 46635671 19 + 0.338 0.444 0.595
ENSG00000160310 E006 1.5982658 0.0087335001 6.827767e-01 8.685848e-01 21 46635672 46635673 2 + 0.383 0.444 0.332
ENSG00000160310 E007 2.8358620 0.0076742170 4.286133e-01 7.071098e-01 21 46635674 46635680 7 + 0.526 0.634 0.488
ENSG00000160310 E008 11.6545428 0.0012077268 3.635546e-02 1.832411e-01 21 46635681 46635763 83 + 1.180 1.007 -0.627
ENSG00000160310 E009 3.4537663 0.0041565119 1.855641e-01 4.633304e-01 21 46635764 46636438 675 + 0.555 0.726 0.738
ENSG00000160310 E010 2.4141984 0.0058876259 1.033135e-01 3.360133e-01 21 46636439 46636443 5 + 0.633 0.402 -1.113
ENSG00000160310 E011 6.2990459 0.0335307122 9.542218e-02 3.215959e-01 21 46636444 46636547 104 + 0.955 0.746 -0.808
ENSG00000160310 E012 17.8850857 0.0019270432 1.361471e-04 3.059193e-03 21 46636896 46636990 95 + 1.390 1.121 -0.949
ENSG00000160310 E013 1.1225145 0.0844921278 9.650538e-02 3.235170e-01 21 46643286 46643534 249 + 0.168 0.444 1.917
ENSG00000160310 E014 21.5910639 0.0008840214 2.885147e-03 3.353611e-02 21 46643535 46643639 105 + 1.438 1.250 -0.653
ENSG00000160310 E015 9.0875769 0.0016886273 3.102325e-01 6.034733e-01 21 46644306 46644310 5 + 0.955 1.048 0.344
ENSG00000160310 E016 11.9397682 0.0013320757 2.975586e-01 5.906708e-01 21 46644311 46644342 32 + 1.152 1.067 -0.305
ENSG00000160310 E017 34.8422493 0.0006707074 4.546786e-02 2.085613e-01 21 46644343 46644488 146 + 1.601 1.502 -0.338
ENSG00000160310 E018 0.2340080 0.2178184653 3.178976e-01   21 46648318 46648457 140 + 0.168 0.000 -12.750
ENSG00000160310 E019 23.6783869 0.0053409136 4.855839e-01 7.493849e-01 21 46648458 46648507 50 + 1.415 1.369 -0.159
ENSG00000160310 E020 34.4430720 0.0004608169 5.684834e-01 8.059437e-01 21 46648508 46648619 112 + 1.563 1.535 -0.095
ENSG00000160310 E021 0.6005290 0.0152035541 2.004015e-01 4.823481e-01 21 46649513 46649574 62 + 0.288 0.098 -1.890
ENSG00000160310 E022 41.1139876 0.0003912115 7.878544e-03 6.841433e-02 21 46649575 46649739 165 + 1.680 1.560 -0.408
ENSG00000160310 E023 3.9034800 0.0144535030 6.361096e-01 8.448150e-01 21 46649740 46649920 181 + 0.719 0.659 -0.253
ENSG00000160310 E024 3.0679744 0.0046306200 7.012919e-01 8.783159e-01 21 46651806 46652318 513 + 0.583 0.634 0.225
ENSG00000160310 E025 1.5956540 0.0083257116 6.827766e-01 8.685848e-01 21 46652845 46652952 108 + 0.383 0.444 0.332
ENSG00000160310 E026 26.5076488 0.0005307496 2.416441e-07 1.286558e-05 21 46656823 46658744 1922 + 1.266 1.563 1.030
ENSG00000160310 E027 37.8834658 0.0004059199 7.118344e-01 8.834878e-01 21 46658745 46658920 176 + 1.598 1.581 -0.058
ENSG00000160310 E028 111.2525669 0.0003071335 4.599251e-03 4.667972e-02 21 46658921 46660656 1736 + 2.012 2.086 0.247
ENSG00000160310 E029 17.4331725 0.0008214923 1.961119e-01 4.767252e-01 21 46660833 46660962 130 + 1.219 1.308 0.313
ENSG00000160310 E030 9.4740525 0.0015004437 6.309674e-06 2.294713e-04 21 46660963 46661799 837 + 0.757 1.183 1.595
ENSG00000160310 E031 9.7020863 0.0019339962 5.800792e-02 2.411034e-01 21 46661800 46661936 137 + 1.107 0.936 -0.627
ENSG00000160310 E032 13.0663715 0.0131625992 6.600923e-01 8.580929e-01 21 46663383 46663554 172 + 1.166 1.129 -0.133
ENSG00000160310 E033 35.3507421 0.0021444644 9.878050e-02 3.280155e-01 21 46664295 46665124 830 + 1.516 1.601 0.290

Help

Please Click HERE to learn more details about the results from DEXseq.