ENSG00000160633

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000292123 ENSG00000160633 No_inf pgKDN_inf SAFB protein_coding protein_coding 65.06967 66.59296 63.89672 2.64116 1.353373 -0.05961858 4.671642 7.715746 0.5040303 5.1143889 0.5040303 -3.9097487 0.06966667 0.109075 0.008025 -0.101050 0.772606708 0.004499555 FALSE TRUE
ENST00000588852 ENSG00000160633 No_inf pgKDN_inf SAFB protein_coding protein_coding 65.06967 66.59296 63.89672 2.64116 1.353373 -0.05961858 13.435349 11.242522 21.6416003 4.2031924 2.0939154 0.9442253 0.20820000 0.172725 0.338800 0.166075 0.601811085 0.004499555 FALSE TRUE
ENST00000590485 ENSG00000160633 No_inf pgKDN_inf SAFB protein_coding retained_intron 65.06967 66.59296 63.89672 2.64116 1.353373 -0.05961858 5.712906 7.535605 5.1470665 0.7443848 0.7230285 -0.5490860 0.08745000 0.112525 0.080200 -0.032325 0.735587350 0.004499555   FALSE
ENST00000592224 ENSG00000160633 No_inf pgKDN_inf SAFB protein_coding protein_coding 65.06967 66.59296 63.89672 2.64116 1.353373 -0.05961858 21.097484 22.055880 10.7806797 1.3788989 6.2378152 -1.0320315 0.32730000 0.334900 0.174300 -0.160600 0.663403882 0.004499555 FALSE TRUE
ENST00000592396 ENSG00000160633 No_inf pgKDN_inf SAFB protein_coding retained_intron 65.06967 66.59296 63.89672 2.64116 1.353373 -0.05961858 5.814077 7.866883 4.9017247 1.7042765 1.7578094 -0.6813951 0.08794167 0.116950 0.075500 -0.041450 0.781184661 0.004499555 FALSE FALSE
MSTRG.14361.2 ENSG00000160633 No_inf pgKDN_inf SAFB protein_coding   65.06967 66.59296 63.89672 2.64116 1.353373 -0.05961858 7.125844 0.000000 16.0041269 0.0000000 7.0591105 10.6451294 0.10835833 0.000000 0.245500 0.245500 0.004499555 0.004499555 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000160633 E001 0.0000000       19 5623035 5623080 46 +      
ENSG00000160633 E002 0.1170040 0.0116776412 5.131686e-01   19 5623081 5623081 1 + 0.097 0.000 -10.611
ENSG00000160633 E003 0.2441403 0.0161715342 9.697701e-01   19 5623082 5623082 1 + 0.097 0.093 -0.065
ENSG00000160633 E004 0.7161162 0.0134946039 8.253775e-02 2.959441e-01 19 5623083 5623098 16 + 0.353 0.093 -2.387
ENSG00000160633 E005 2.3163657 0.0085403385 4.339669e-01 7.112427e-01 19 5623099 5623117 19 + 0.575 0.465 -0.525
ENSG00000160633 E006 2.3163657 0.0085403385 4.339669e-01 7.112427e-01 19 5623118 5623120 3 + 0.575 0.465 -0.525
ENSG00000160633 E007 2.4339964 0.0068912258 3.214530e-01 6.145157e-01 19 5623121 5623121 1 + 0.603 0.465 -0.650
ENSG00000160633 E008 3.3936860 0.0042329703 1.032148e-01 3.357937e-01 19 5623122 5623138 17 + 0.741 0.531 -0.913
ENSG00000160633 E009 43.6867961 0.0003415012 1.763099e-02 1.167047e-01 19 5623139 5623394 256 + 1.702 1.597 -0.356
ENSG00000160633 E010 31.9072767 0.0010221095 2.400258e-01 5.292323e-01 19 5626405 5626489 85 + 1.548 1.487 -0.209
ENSG00000160633 E011 33.7832734 0.0125629095 7.860639e-01 9.175736e-01 19 5641594 5641658 65 + 1.551 1.532 -0.065
ENSG00000160633 E012 45.7231674 0.0003192413 9.994063e-01 1.000000e+00 19 5641740 5641850 111 + 1.668 1.669 0.004
ENSG00000160633 E013 40.4095559 0.0003613107 5.826353e-01 8.140473e-01 19 5641851 5641946 96 + 1.629 1.605 -0.083
ENSG00000160633 E014 28.8114486 0.0005588370 9.299143e-01 9.794364e-01 19 5645337 5645399 63 + 1.470 1.476 0.021
ENSG00000160633 E015 17.5917003 0.0046133652 2.933687e-01 5.869656e-01 19 5648016 5648043 28 + 1.307 1.231 -0.266
ENSG00000160633 E016 11.3981763 0.0012338205 7.176682e-03 6.410625e-02 19 5648044 5648404 361 + 0.955 1.186 0.842
ENSG00000160633 E017 0.0000000       19 5648855 5648988 134 +      
ENSG00000160633 E018 24.0146877 0.0006945362 1.008950e-04 2.391943e-03 19 5648989 5649499 511 + 1.506 1.272 -0.810
ENSG00000160633 E019 7.9273769 0.0617039383 9.449235e-02 3.199015e-01 19 5649684 5649925 242 + 0.813 1.043 0.868
ENSG00000160633 E020 26.6307316 0.0011584899 2.503787e-01 5.414689e-01 19 5649926 5649975 50 + 1.474 1.409 -0.224
ENSG00000160633 E021 38.3587363 0.0004219566 8.842110e-01 9.610847e-01 19 5650978 5651072 95 + 1.597 1.592 -0.019
ENSG00000160633 E022 51.6452581 0.0002953751 5.932611e-01 8.206909e-01 19 5653115 5653264 150 + 1.708 1.731 0.079
ENSG00000160633 E023 50.2726299 0.0034361386 7.272539e-01 8.910835e-01 19 5653338 5653420 83 + 1.700 1.718 0.062
ENSG00000160633 E024 83.4115766 0.0027105436 1.375309e-01 3.947627e-01 19 5654061 5654200 140 + 1.894 1.952 0.195
ENSG00000160633 E025 66.2097139 0.0002112601 1.604489e-01 4.282503e-01 19 5654368 5654456 89 + 1.798 1.850 0.176
ENSG00000160633 E026 57.4624555 0.0019904421 7.267577e-01 8.907457e-01 19 5657241 5657324 84 + 1.773 1.759 -0.047
ENSG00000160633 E027 25.3422068 0.0047664095 2.022018e-02 1.278777e-01 19 5657325 5657347 23 + 1.492 1.344 -0.513
ENSG00000160633 E028 0.2542726 0.2131670081 3.080517e-01   19 5661488 5661517 30 + 0.000 0.170 11.376
ENSG00000160633 E029 8.9196300 0.0140104221 3.610644e-01 6.506614e-01 19 5661518 5661520 3 + 1.042 0.949 -0.343
ENSG00000160633 E030 93.3659993 0.0001954623 1.361122e-02 9.820833e-02 19 5661521 5661808 288 + 2.011 1.938 -0.247
ENSG00000160633 E031 37.4227968 0.0004237944 5.788680e-01 8.118088e-01 19 5664022 5664128 107 + 1.569 1.597 0.096
ENSG00000160633 E032 20.9549340 0.0006616556 9.323402e-01 9.803068e-01 19 5664129 5664159 31 + 1.343 1.339 -0.015
ENSG00000160633 E033 23.5390062 0.0005866071 9.643177e-01 9.924532e-01 19 5664397 5664439 43 + 1.390 1.388 -0.005
ENSG00000160633 E034 2.5052502 0.0066683115 8.406237e-03 7.150029e-02 19 5664440 5664725 286 + 0.301 0.684 1.935
ENSG00000160633 E035 25.7782975 0.0008949159 2.563982e-10 2.426067e-08 19 5664726 5666655 1930 + 1.177 1.570 1.366
ENSG00000160633 E036 5.6764156 0.0024700397 1.932142e-01 4.730284e-01 19 5666656 5667045 390 + 0.741 0.887 0.572
ENSG00000160633 E037 37.7834068 0.0088759500 9.035141e-01 9.690403e-01 19 5667046 5667164 119 + 1.583 1.592 0.028
ENSG00000160633 E038 1.2461553 0.0122791181 2.342099e-01 5.232141e-01 19 5667165 5667346 182 + 0.243 0.427 1.157
ENSG00000160633 E039 10.1047018 0.0261426170 3.331814e-01 6.252435e-01 19 5667347 5667352 6 + 0.990 1.088 0.360
ENSG00000160633 E040 38.6036554 0.0004175489 7.956632e-01 9.223707e-01 19 5667353 5667450 98 + 1.603 1.592 -0.038
ENSG00000160633 E041 1.3703036 0.1168058363 2.135500e-01 4.987385e-01 19 5667451 5667819 369 + 0.243 0.465 1.350
ENSG00000160633 E042 41.4558211 0.0004198177 8.326615e-01 9.396515e-01 19 5667820 5667886 67 + 1.621 1.632 0.037
ENSG00000160633 E043 78.3489278 0.0002029100 1.864802e-01 4.644696e-01 19 5668162 5668478 317 + 1.874 1.919 0.152

Help

Please Click HERE to learn more details about the results from DEXseq.