ENSG00000160695

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000524454 ENSG00000160695 No_inf pgKDN_inf VPS11 protein_coding protein_coding_CDS_not_defined 41.3577 45.95805 38.41824 3.156177 1.000022 -0.2584647 13.380672 18.860946 9.202449 3.3435318 0.6517862 -1.0345101 0.31426667 0.401075 0.238975 -0.16210 0.203003865 0.0014413   FALSE
ENST00000530809 ENSG00000160695 No_inf pgKDN_inf VPS11 protein_coding protein_coding 41.3577 45.95805 38.41824 3.156177 1.000022 -0.2584647 1.094884 2.489858 0.000000 0.7197666 0.0000000 -7.9657026 0.02558333 0.056650 0.000000 -0.05665 0.001441300 0.0014413 FALSE FALSE
ENST00000621676 ENSG00000160695 No_inf pgKDN_inf VPS11 protein_coding protein_coding 41.3577 45.95805 38.41824 3.156177 1.000022 -0.2584647 22.701528 18.861536 26.251225 0.5702774 0.5577123 0.4767223 0.56120833 0.419075 0.683625 0.26455 0.002566129 0.0014413 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000160695 E001 1.9660180 0.0090858190 0.6286364553 0.84064461 11 119067818 119067820 3 + 0.434 0.505 0.356
ENSG00000160695 E002 2.3380821 0.0061242306 0.5019428850 0.76170585 11 119067821 119067822 2 + 0.472 0.567 0.453
ENSG00000160695 E003 12.6442930 0.0082375124 0.0993435663 0.32916748 11 119067823 119068010 188 + 1.203 1.061 -0.511
ENSG00000160695 E004 0.3816610 0.0278870718 0.1056048279   11 119068011 119068012 2 + 0.000 0.239 10.466
ENSG00000160695 E005 1.6177762 0.0172063485 0.1731453259 0.44624676 11 119068013 119068202 190 + 0.297 0.505 1.163
ENSG00000160695 E006 0.4896297 0.0158291547 0.9972022552   11 119069173 119069195 23 + 0.173 0.173 -0.007
ENSG00000160695 E007 2.6464125 0.0084287208 0.0324380507 0.17061769 11 119069196 119069197 2 + 0.692 0.392 -1.422
ENSG00000160695 E008 14.7946879 0.0009462732 0.6341587440 0.84363916 11 119069198 119069344 147 + 1.216 1.181 -0.126
ENSG00000160695 E009 14.7039448 0.0010597479 0.0131392380 0.09603627 11 119069442 119069552 111 + 1.282 1.096 -0.661
ENSG00000160695 E010 6.6744779 0.0283567727 0.0807264949 0.29201271 11 119069553 119069577 25 + 0.982 0.770 -0.814
ENSG00000160695 E011 18.3948123 0.0031218256 0.8881028963 0.96257330 11 119070234 119070397 164 + 1.282 1.291 0.032
ENSG00000160695 E012 1.4803816 0.0090110251 0.5724973129 0.80844071 11 119070398 119070784 387 + 0.348 0.433 0.479
ENSG00000160695 E013 26.0278972 0.0034803036 0.2670601822 0.56035228 11 119071596 119071843 248 + 1.466 1.397 -0.238
ENSG00000160695 E014 3.2303628 0.0053655301 0.0510995833 0.22380613 11 119072032 119073197 1166 + 0.472 0.732 1.163
ENSG00000160695 E015 27.9895370 0.0006193819 0.3693082654 0.65754757 11 119073198 119073399 202 + 1.487 1.437 -0.171
ENSG00000160695 E016 2.8648175 0.0128256005 0.0242027411 0.14252918 11 119073400 119073799 400 + 0.393 0.712 1.496
ENSG00000160695 E017 9.8103487 0.0089590998 0.8489616860 0.94642935 11 119073800 119073821 22 + 1.024 1.042 0.066
ENSG00000160695 E018 21.0037319 0.0110283706 0.3352359579 0.62708060 11 119073822 119073951 130 + 1.304 1.375 0.247
ENSG00000160695 E019 1.7688664 0.0396420591 0.0009843602 0.01483389 11 119076819 119076896 78 + 0.095 0.621 3.694
ENSG00000160695 E020 23.4384670 0.0006857703 0.2341367442 0.52317733 11 119076897 119077019 123 + 1.423 1.352 -0.248
ENSG00000160695 E021 14.2962729 0.0010720808 0.0015429068 0.02089782 11 119077020 119077083 64 + 1.293 1.051 -0.862
ENSG00000160695 E022 28.0935265 0.0067630142 0.0166901385 0.11266157 11 119077501 119077647 147 + 1.536 1.384 -0.524
ENSG00000160695 E023 32.5157782 0.0052896156 0.5082615181 0.76658924 11 119077878 119078066 189 + 1.545 1.505 -0.137
ENSG00000160695 E024 0.4985390 0.0370534604 0.3266083241   11 119078145 119078172 28 + 0.095 0.239 1.579
ENSG00000160695 E025 29.3023922 0.0005007427 0.7667955094 0.90959045 11 119078173 119078334 162 + 1.473 1.488 0.054
ENSG00000160695 E026 1.3773871 0.1133850404 0.0620015133 0.25012077 11 119078335 119078564 230 + 0.173 0.505 2.163
ENSG00000160695 E027 27.3677380 0.0005856056 0.3970966801 0.68145583 11 119078565 119078704 140 + 1.427 1.474 0.162
ENSG00000160695 E028 1.7426814 0.0077682261 0.1088955375 0.34643850 11 119078705 119078794 90 + 0.297 0.537 1.315
ENSG00000160695 E029 45.5205050 0.0003556024 0.5669433030 0.80486506 11 119078795 119078997 203 + 1.680 1.655 -0.084
ENSG00000160695 E030 24.5026139 0.0081315001 0.8356522849 0.94095934 11 119079129 119079181 53 + 1.399 1.413 0.051
ENSG00000160695 E031 37.7748471 0.0007258800 0.5143527266 0.77103210 11 119079182 119079300 119 + 1.572 1.603 0.106
ENSG00000160695 E032 67.0893716 0.0002659061 0.3282197951 0.62072374 11 119081092 119081314 223 + 1.815 1.849 0.115
ENSG00000160695 E033 97.7950651 0.0003339277 0.0009843228 0.01483389 11 119081459 119081972 514 + 1.943 2.037 0.318

Help

Please Click HERE to learn more details about the results from DEXseq.