ENSG00000160785

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000359511 ENSG00000160785 No_inf pgKDN_inf SLC25A44 protein_coding protein_coding 21.32787 16.05452 24.6268 0.180557 0.8600026 0.616937 13.071682 7.467759 17.733854 0.5769977 0.8829006 1.24664158 0.59630 0.466100 0.72025 0.254150 0.02902834 0.02902834 FALSE TRUE
ENST00000468973 ENSG00000160785 No_inf pgKDN_inf SLC25A44 protein_coding protein_coding_CDS_not_defined 21.32787 16.05452 24.6268 0.180557 0.8600026 0.616937 1.747409 3.797823 1.444404 2.2105760 1.4444041 -1.38853836 0.09835 0.236600 0.05845 -0.178150 0.76215528 0.02902834 FALSE FALSE
ENST00000684582 ENSG00000160785 No_inf pgKDN_inf SLC25A44 protein_coding protein_coding 21.32787 16.05452 24.6268 0.180557 0.8600026 0.616937 4.067485 3.774757 3.687755 2.2469092 1.7274144 -0.03355098 0.19500 0.234325 0.14750 -0.086825 0.96566276 0.02902834 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000160785 E001 0.3635961 0.0167928084 0.8122410976   1 156193932 156194102 171 + 0.150 0.111 -0.511
ENSG00000160785 E002 0.3635961 0.0167928084 0.8122410976   1 156194103 156194103 1 + 0.150 0.111 -0.511
ENSG00000160785 E003 6.8594778 0.0163872432 0.0267497722 0.151721760 1 156194104 156194247 144 + 0.986 0.728 -0.996
ENSG00000160785 E004 0.8450736 0.0952987285 0.5048940114 0.763863923 1 156196132 156196173 42 + 0.308 0.199 -0.833
ENSG00000160785 E005 11.7966499 0.0278778614 0.0326874051 0.171394372 1 156196205 156199617 3413 + 0.995 1.214 0.791
ENSG00000160785 E006 1.3512028 0.0100574948 0.3977129008 0.681879734 1 156199618 156199721 104 + 0.308 0.438 0.752
ENSG00000160785 E007 0.7537251 0.0133545109 0.0380190951 0.188076024 1 156199722 156199834 113 + 0.082 0.389 2.811
ENSG00000160785 E008 38.5435559 0.0003900072 0.0001121193 0.002612113 1 156199835 156200389 555 + 1.663 1.481 -0.621
ENSG00000160785 E009 12.2249958 0.0011749256 0.1447964812 0.405054638 1 156200390 156200472 83 + 1.165 1.047 -0.426
ENSG00000160785 E010 0.8681460 0.0282660283 0.1201521940 0.366469967 1 156207862 156207885 24 + 0.150 0.389 1.811
ENSG00000160785 E011 16.2846219 0.0017979781 0.7406608838 0.897148601 1 156207886 156208013 128 + 1.244 1.222 -0.078
ENSG00000160785 E012 259.9436851 0.0001178594 0.0054298305 0.052548444 1 156210240 156212796 2557 + 2.400 2.429 0.096

Help

Please Click HERE to learn more details about the results from DEXseq.