ENSG00000160877

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000292431 ENSG00000160877 No_inf pgKDN_inf NACC1 protein_coding protein_coding 32.36258 24.08427 35.17813 0.8231819 1.216655 0.5463989 16.933199 7.996704 21.630888 0.7791100 1.2637737 1.4344794 0.5022917 0.332500 0.616525 0.284025 0.00978317 0.00978317 FALSE TRUE
ENST00000585663 ENSG00000160877 No_inf pgKDN_inf NACC1 protein_coding protein_coding 32.36258 24.08427 35.17813 0.8231819 1.216655 0.5463989 11.499368 10.513500 11.562254 0.8985868 1.1030717 0.1370552 0.3635583 0.436075 0.326800 -0.109275 0.55623635 0.00978317   TRUE
MSTRG.14626.3 ENSG00000160877 No_inf pgKDN_inf NACC1 protein_coding   32.36258 24.08427 35.17813 0.8231819 1.216655 0.5463989 2.551825 3.311874 1.445744 0.4401817 0.3337551 -1.1902407 0.0857750 0.139225 0.041075 -0.098150 0.14835705 0.00978317 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000160877 E001 0.0000000       19 13116862 13116935 74 +      
ENSG00000160877 E002 0.4997349 0.0267995185 1.955144e-01   19 13117994 13118131 138 + 0.083 0.269 2.035
ENSG00000160877 E003 3.0077176 0.0100571726 1.493651e-01 4.116048e-01 19 13118264 13118299 36 + 0.678 0.478 -0.912
ENSG00000160877 E004 5.8045813 0.0024750148 2.071022e-01 4.906806e-01 19 13118300 13118399 100 + 0.887 0.746 -0.550
ENSG00000160877 E005 3.9943670 0.0915070765 3.706996e-01 6.589885e-01 19 13118400 13118454 55 + 0.749 0.618 -0.549
ENSG00000160877 E006 0.4993265 0.0151829666 1.927244e-01   19 13118455 13118725 271 + 0.083 0.269 2.035
ENSG00000160877 E007 0.5078857 0.0157715522 2.097409e-02 1.307311e-01 19 13135175 13135199 25 + 0.000 0.331 10.888
ENSG00000160877 E008 83.9523161 0.0002905180 7.950056e-02 2.892106e-01 19 13135200 13136153 954 + 1.949 1.895 -0.182
ENSG00000160877 E009 33.4649473 0.0004420734 7.702562e-01 9.114498e-01 19 13136232 13136405 174 + 1.540 1.527 -0.048
ENSG00000160877 E010 10.8282676 0.0034420211 7.308180e-01 8.930691e-01 19 13137271 13137278 8 + 1.083 1.053 -0.108
ENSG00000160877 E011 12.5198423 0.0025695154 6.167776e-01 8.340090e-01 19 13137279 13137314 36 + 1.146 1.105 -0.146
ENSG00000160877 E012 15.3076478 0.0080407938 4.737639e-01 7.407231e-01 19 13137315 13137376 62 + 1.234 1.177 -0.202
ENSG00000160877 E013 18.4489190 0.0008066778 2.962180e-01 5.892893e-01 19 13137478 13137575 98 + 1.316 1.245 -0.246
ENSG00000160877 E014 9.4440585 0.0017420697 1.655681e-06 7.218877e-05 19 13137576 13138146 571 + 0.765 1.209 1.655
ENSG00000160877 E015 10.7036185 0.0036773122 7.945136e-01 9.217314e-01 19 13138147 13138157 11 + 1.075 1.053 -0.080
ENSG00000160877 E016 356.8005917 0.0001178082 1.317928e-01 3.851591e-01 19 13138158 13141147 2990 + 2.544 2.559 0.053

Help

Please Click HERE to learn more details about the results from DEXseq.