ENSG00000160948

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000292510 ENSG00000160948 No_inf pgKDN_inf VPS28 protein_coding protein_coding 131.4834 156.7419 120.3499 3.69773 7.642731 -0.3811281 86.331987 98.021198 79.424285 4.583485 6.894332 -0.3034791 0.66473333 0.626100 0.670525 0.044425 0.83688425 0.01342624 FALSE  
ENST00000526734 ENSG00000160948 No_inf pgKDN_inf VPS28 protein_coding protein_coding_CDS_not_defined 131.4834 156.7419 120.3499 3.69773 7.642731 -0.3811281 5.457476 10.566452 0.000000 4.447570 0.000000 -10.0466401 0.03842500 0.065900 0.000000 -0.065900 0.01342624 0.01342624    
ENST00000531032 ENSG00000160948 No_inf pgKDN_inf VPS28 protein_coding protein_coding 131.4834 156.7419 120.3499 3.69773 7.642731 -0.3811281 6.491406 3.771476 15.702741 3.771476 9.292079 2.0549134 0.04977500 0.025825 0.123500 0.097675 0.83428937 0.01342624 FALSE  
ENST00000533806 ENSG00000160948 No_inf pgKDN_inf VPS28 protein_coding protein_coding 131.4834 156.7419 120.3499 3.69773 7.642731 -0.3811281 10.776511 17.215490 7.672182 4.447516 4.200852 -1.1649570 0.07689167 0.109525 0.059375 -0.050150 0.54028660 0.01342624 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000160948 E001 0.1187032 0.0117868927 0.330647695   8 144423601 144423616 16 - 0.117 0.000 -9.572
ENSG00000160948 E002 0.6093096 0.1923346287 0.389203726 0.675048680 8 144423617 144423619 3 - 0.285 0.142 -1.256
ENSG00000160948 E003 0.6093096 0.1923346287 0.389203726 0.675048680 8 144423620 144423620 1 - 0.285 0.142 -1.256
ENSG00000160948 E004 2.3583170 0.0077154262 0.531371438 0.782006853 8 144423621 144423621 1 - 0.455 0.547 0.444
ENSG00000160948 E005 6.9013922 0.0022712805 0.703531309 0.879418213 8 144423622 144423630 9 - 0.909 0.869 -0.150
ENSG00000160948 E006 17.0049224 0.0007760087 0.510605280 0.768055968 8 144423631 144423671 41 - 1.270 1.223 -0.164
ENSG00000160948 E007 91.6110426 0.0001611682 0.230732190 0.519183526 8 144423672 144423863 192 - 1.974 1.937 -0.125
ENSG00000160948 E008 62.4198093 0.0002274752 0.522498820 0.775952982 8 144423864 144423922 59 - 1.802 1.778 -0.081
ENSG00000160948 E009 9.8371590 0.0015098518 0.026452233 0.150715693 8 144423923 144424040 118 - 0.874 1.088 0.795
ENSG00000160948 E010 77.0844769 0.0003067167 0.645508023 0.849950678 8 144424041 144424104 64 - 1.867 1.883 0.056
ENSG00000160948 E011 64.0647151 0.0003400528 0.211818233 0.496826858 8 144424105 144424132 28 - 1.767 1.816 0.165
ENSG00000160948 E012 4.3729870 0.0033418285 0.050533101 0.222141353 8 144424133 144424214 82 - 0.540 0.795 1.084
ENSG00000160948 E013 94.3066234 0.0001762812 0.396550330 0.681239850 8 144424215 144424268 54 - 1.946 1.974 0.091
ENSG00000160948 E014 34.4262575 0.0006272930 0.003023982 0.034708763 8 144424269 144424717 449 - 1.425 1.587 0.554
ENSG00000160948 E015 133.0496938 0.0001338541 0.538813144 0.787369373 8 144424718 144424819 102 - 2.121 2.106 -0.051
ENSG00000160948 E016 16.9699449 0.0008084188 0.000442467 0.007938794 8 144424820 144424945 126 - 1.049 1.322 0.971
ENSG00000160948 E017 77.3274701 0.0002252536 0.847060623 0.945708696 8 144424946 144424964 19 - 1.874 1.881 0.024
ENSG00000160948 E018 78.1887303 0.0002585095 0.300071197 0.593016610 8 144424965 144425000 36 - 1.905 1.870 -0.118
ENSG00000160948 E019 84.3423888 0.0002857560 0.022345469 0.135942463 8 144425001 144425051 51 - 1.961 1.887 -0.251
ENSG00000160948 E020 22.6882335 0.0006475539 0.145715285 0.406388773 8 144425052 144425395 344 - 1.298 1.392 0.329
ENSG00000160948 E021 23.4592993 0.0081012107 0.000643528 0.010610834 8 144425396 144425682 287 - 1.191 1.453 0.914
ENSG00000160948 E022 93.2783568 0.0001708834 0.005263299 0.051519197 8 144425683 144425717 35 - 2.011 1.925 -0.288
ENSG00000160948 E023 100.3386646 0.0001599884 0.102104529 0.333913756 8 144425718 144425772 55 - 2.020 1.972 -0.162
ENSG00000160948 E024 6.5922744 0.0207910776 0.163516462 0.432372253 8 144425773 144425874 102 - 0.751 0.923 0.670
ENSG00000160948 E025 4.9869936 0.0033519491 0.073005072 0.274542255 8 144425875 144425921 47 - 0.612 0.834 0.914
ENSG00000160948 E026 10.1959277 0.0012820662 0.080914324 0.292305964 8 144425922 144426025 104 - 0.925 1.088 0.602
ENSG00000160948 E027 58.2041860 0.0002574179 0.661501835 0.858724817 8 144426026 144426059 34 - 1.746 1.764 0.061
ENSG00000160948 E028 32.2252581 0.0004993588 0.861026086 0.951853949 8 144426060 144426063 4 - 1.512 1.503 -0.031
ENSG00000160948 E029 3.0115328 0.0500678852 0.039629733 0.193006605 8 144426064 144426179 116 - 0.349 0.688 1.651
ENSG00000160948 E030 38.1736513 0.0060554418 0.225492783 0.513307335 8 144426180 144426208 29 - 1.621 1.551 -0.239
ENSG00000160948 E031 8.1635181 0.0204879644 0.724867804 0.889526227 8 144426209 144426470 262 - 0.925 0.961 0.136
ENSG00000160948 E032 9.6663861 0.0014407096 0.343985714 0.635360462 8 144426471 144426908 438 - 0.956 1.045 0.329
ENSG00000160948 E033 42.0665724 0.0003196156 0.536652587 0.785897543 8 144426909 144426979 71 - 1.637 1.608 -0.097
ENSG00000160948 E034 4.3122185 0.0307766065 0.611765057 0.831065492 8 144426980 144427291 312 - 0.751 0.688 -0.256
ENSG00000160948 E035 0.2533610 0.0160590685 0.449379366   8 144427292 144427294 3 - 0.000 0.142 10.260
ENSG00000160948 E036 17.5409172 0.0015130846 0.964635664 0.992534242 8 144428489 144428563 75 - 1.255 1.252 -0.009

Help

Please Click HERE to learn more details about the results from DEXseq.