ENSG00000160959

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000292524 ENSG00000160959 No_inf pgKDN_inf LRRC14 protein_coding protein_coding 13.88279 14.0304 13.41278 1.11614 1.265855 -0.06490118 3.3305117 2.904893 1.3153449 0.9714916 1.0658368 -1.13707481 0.24656667 0.218675 0.113900 -0.104775 0.71147559 0.04416623 FALSE TRUE
ENST00000528528 ENSG00000160959 No_inf pgKDN_inf LRRC14 protein_coding protein_coding_CDS_not_defined 13.88279 14.0304 13.41278 1.11614 1.265855 -0.06490118 2.4339685 3.864480 1.6332365 0.8850382 0.9520494 -1.23746266 0.16542500 0.268350 0.104725 -0.163625 0.46150180 0.04416623 TRUE TRUE
ENST00000531310 ENSG00000160959 No_inf pgKDN_inf LRRC14 protein_coding retained_intron 13.88279 14.0304 13.41278 1.11614 1.265855 -0.06490118 1.8112449 2.110790 2.0894315 0.3806242 0.6380026 -0.01460297 0.12820833 0.148800 0.148950 0.000150 1.00000000 0.04416623 FALSE FALSE
MSTRG.28394.10 ENSG00000160959 No_inf pgKDN_inf LRRC14 protein_coding   13.88279 14.0304 13.41278 1.11614 1.265855 -0.06490118 1.4729372 2.747743 0.4936602 0.2093543 0.1287874 -2.45296541 0.10792500 0.200825 0.037300 -0.163525 0.04416623 0.04416623 FALSE TRUE
MSTRG.28394.2 ENSG00000160959 No_inf pgKDN_inf LRRC14 protein_coding   13.88279 14.0304 13.41278 1.11614 1.265855 -0.06490118 2.9745192 1.598836 5.6817418 1.1375977 1.9196597 1.82285314 0.21304167 0.109975 0.418950 0.308975 0.50798492 0.04416623 FALSE TRUE
MSTRG.28394.7 ENSG00000160959 No_inf pgKDN_inf LRRC14 protein_coding   13.88279 14.0304 13.41278 1.11614 1.265855 -0.06490118 0.7752479 0.000000 1.0496703 0.0000000 1.0496703 6.72747162 0.06133333 0.000000 0.089750 0.089750 0.84495250 0.04416623 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000160959 E001 0.1170040 0.0116446566 0.5162201917   8 144517987 144517991 5 + 0.098 0.000 -10.826
ENSG00000160959 E002 0.4680160 0.6485729399 0.2797461453   8 144517992 144517995 4 + 0.303 0.000 -14.136
ENSG00000160959 E003 0.7043498 0.0170636649 0.0084734339 0.07186621 8 144517996 144518000 5 + 0.402 0.000 -15.383
ENSG00000160959 E004 0.8308568 0.0156464847 0.0449488648 0.20725588 8 144518001 144518001 1 + 0.402 0.092 -2.688
ENSG00000160959 E005 0.9581191 0.0143112479 0.1385218021 0.39586212 8 144518002 144518004 3 + 0.402 0.168 -1.688
ENSG00000160959 E006 3.2809989 0.0044868651 0.2884485777 0.58200956 8 144518005 144518041 37 + 0.704 0.556 -0.644
ENSG00000160959 E007 0.9885130 0.0122147736 0.5185203101 0.77351402 8 144518292 144518370 79 + 0.246 0.339 0.634
ENSG00000160959 E008 3.6349388 0.0042806648 0.0003812309 0.00703191 8 144518371 144518744 374 + 0.356 0.824 2.160
ENSG00000160959 E009 0.7611821 0.0246311700 0.0113442975 0.08739273 8 144518745 144518748 4 + 0.000 0.383 14.497
ENSG00000160959 E010 1.3781418 0.0094589571 0.0347398661 0.17812149 8 144518749 144518815 67 + 0.178 0.495 2.067
ENSG00000160959 E011 2.1035997 0.0067201940 0.2592405970 0.55182015 8 144519097 144519240 144 + 0.402 0.556 0.771
ENSG00000160959 E012 5.4192217 0.0030762167 0.2836155964 0.57735803 8 144519267 144519614 348 + 0.746 0.854 0.428
ENSG00000160959 E013 2.8255041 0.0716962771 0.9652869924 0.99272752 8 144519615 144519700 86 + 0.579 0.584 0.022
ENSG00000160959 E014 16.1823761 0.0008731204 0.9074377493 0.97060423 8 144519701 144520054 354 + 1.236 1.232 -0.016
ENSG00000160959 E015 2.0571091 0.0762384626 0.2712130141 0.56495835 8 144520238 144520241 4 + 0.579 0.383 -0.977
ENSG00000160959 E016 30.3666513 0.0104235028 0.0340666879 0.17589056 8 144520242 144520822 581 + 1.566 1.423 -0.488
ENSG00000160959 E017 68.2580680 0.0118308895 0.3135758045 0.60674454 8 144520911 144522403 1493 + 1.870 1.811 -0.196
ENSG00000160959 E018 0.0000000       8 144522404 144522581 178 +      
ENSG00000160959 E019 0.0000000       8 144522582 144523271 690 +      
ENSG00000160959 E020 0.0000000       8 144523272 144523333 62 +      
ENSG00000160959 E021 13.1514017 0.0011242318 0.3869290413 0.67281268 8 144523334 144523635 302 + 1.120 1.174 0.195
ENSG00000160959 E022 7.1788827 0.0060511266 0.1941447635 0.47395712 8 144523636 144523662 27 + 0.983 0.839 -0.547
ENSG00000160959 E023 21.6494222 0.0022417601 0.6171699871 0.83422586 8 144523663 144523809 147 + 1.377 1.333 -0.152
ENSG00000160959 E024 17.3244046 0.0009287233 0.2942737017 0.58758868 8 144523810 144523923 114 + 1.230 1.288 0.205
ENSG00000160959 E025 13.2389275 0.0011705074 0.0043611331 0.04507730 8 144523924 144524105 182 + 1.027 1.238 0.758
ENSG00000160959 E026 0.3812526 0.0158862352 0.1111728694   8 144524106 144524260 155 + 0.000 0.233 13.645
ENSG00000160959 E027 14.6681025 0.0025324076 0.1290727195 0.38123812 8 144524261 144525449 1189 + 1.136 1.238 0.362

Help

Please Click HERE to learn more details about the results from DEXseq.