ENSG00000161011

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000389805 ENSG00000161011 No_inf pgKDN_inf SQSTM1 protein_coding protein_coding 228.3939 133.393 267.121 4.842555 9.745973 1.001757 154.20837 93.99057 178.92450 1.067959 2.950186 0.9286902 0.68340000 0.708475 0.673750 -0.034725 0.84231814 0.0002947638 FALSE TRUE
ENST00000466342 ENSG00000161011 No_inf pgKDN_inf SQSTM1 protein_coding retained_intron 228.3939 133.393 267.121 4.842555 9.745973 1.001757 30.98305 17.50718 38.26888 3.648644 5.303098 1.1277779 0.13378333 0.128975 0.141800 0.012825 0.88560838 0.0002947638 FALSE TRUE
ENST00000626660 ENSG00000161011 No_inf pgKDN_inf SQSTM1 protein_coding protein_coding 228.3939 133.393 267.121 4.842555 9.745973 1.001757 26.74127 3.11981 37.11040 3.119810 6.545186 3.5680654 0.09944167 0.022075 0.136925 0.114850 0.03917919 0.0002947638   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000161011 E001 0.0000000       5 179806337 179806397 61 +      
ENSG00000161011 E002 0.0000000       5 179806398 179806407 10 +      
ENSG00000161011 E003 0.0000000       5 179806408 179806449 42 +      
ENSG00000161011 E004 0.0000000       5 179806450 179806591 142 +      
ENSG00000161011 E005 1.0881180 3.654315e-02 7.375086e-01 8.958820e-01 5 179807069 179807123 55 + 0.336 0.284 -0.342
ENSG00000161011 E006 2.8934556 4.899752e-03 2.336360e-06 9.685566e-05 5 179807324 179808427 1104 + 0.200 0.854 3.395
ENSG00000161011 E007 1.7240771 8.803173e-03 1.760937e-01 4.502223e-01 5 179811574 179811614 41 + 0.336 0.539 1.073
ENSG00000161011 E008 2.4861369 7.825381e-03 5.838434e-03 5.533124e-02 5 179811615 179811682 68 + 0.336 0.725 1.880
ENSG00000161011 E009 2.0219111 6.835273e-03 4.051986e-06 1.568843e-04 5 179811988 179812406 419 + 0.077 0.749 4.565
ENSG00000161011 E010 24.8478104 1.059886e-02 4.198566e-19 1.043528e-16 5 179812407 179814174 1768 + 0.998 1.682 2.392
ENSG00000161011 E011 0.0000000       5 179818878 179818966 89 +      
ENSG00000161011 E012 0.0000000       5 179818967 179819037 71 +      
ENSG00000161011 E013 0.1268540 1.227678e-02 3.376443e-01   5 179820104 179820387 284 + 0.000 0.116 9.900
ENSG00000161011 E014 0.0000000       5 179820607 179820706 100 +      
ENSG00000161011 E015 0.0000000       5 179820878 179820884 7 +      
ENSG00000161011 E016 0.4909842 4.376504e-01 7.145072e-01   5 179820885 179820897 13 + 0.143 0.208 0.656
ENSG00000161011 E017 0.8443220 1.323749e-02 5.683985e-01 8.058886e-01 5 179820898 179820904 7 + 0.295 0.208 -0.664
ENSG00000161011 E018 14.7022937 1.838974e-03 7.391569e-01 8.966036e-01 5 179820905 179820920 16 + 1.177 1.206 0.103
ENSG00000161011 E019 95.3597417 2.015853e-04 5.560310e-02 2.349071e-01 5 179820921 179821141 221 + 1.998 1.941 -0.191
ENSG00000161011 E020 0.1176306 1.172026e-02 8.663767e-01   5 179821551 179821611 61 + 0.077 0.000 -9.669
ENSG00000161011 E021 0.8709474 1.245329e-02 8.536635e-02 3.022483e-01 5 179821612 179821707 96 + 0.143 0.404 1.980
ENSG00000161011 E022 14.3526537 1.125286e-02 1.773257e-02 1.171901e-01 5 179822485 179822888 404 + 1.083 1.289 0.732
ENSG00000161011 E023 4.1662808 1.178019e-02 2.135221e-01 4.987385e-01 5 179822889 179822957 69 + 0.635 0.794 0.658
ENSG00000161011 E024 84.5570068 1.987002e-04 3.046313e-01 5.980193e-01 5 179822958 179823025 68 + 1.909 1.946 0.125
ENSG00000161011 E025 73.9267402 1.994678e-04 5.575179e-01 7.994461e-01 5 179823026 179823053 28 + 1.857 1.881 0.081
ENSG00000161011 E026 5.9590086 3.215044e-02 4.593398e-04 8.181648e-03 5 179823565 179823857 293 + 0.594 1.047 1.795
ENSG00000161011 E027 47.1770984 3.265069e-04 6.963302e-01 8.760457e-01 5 179823858 179823859 2 + 1.667 1.687 0.070
ENSG00000161011 E028 242.2719029 1.326119e-04 6.749825e-01 8.653112e-01 5 179823860 179824087 228 + 2.380 2.376 -0.015
ENSG00000161011 E029 197.5904786 1.060170e-04 3.503590e-01 6.405947e-01 5 179824182 179824323 142 + 2.281 2.304 0.077
ENSG00000161011 E030 154.0426078 1.250112e-04 1.358584e-02 9.812250e-02 5 179825146 179825226 81 + 2.205 2.148 -0.190
ENSG00000161011 E031 303.9057919 8.303876e-05 8.935184e-03 7.458756e-02 5 179833032 179833227 196 + 2.492 2.452 -0.133
ENSG00000161011 E032 127.4939242 1.878363e-03 3.042879e-01 5.977586e-01 5 179833228 179833246 19 + 2.113 2.084 -0.097
ENSG00000161011 E033 3.5554694 3.906804e-03 1.704999e-01 4.426778e-01 5 179833247 179833386 140 + 0.571 0.749 0.757
ENSG00000161011 E034 294.7996425 8.944383e-05 1.534719e-01 4.181096e-01 5 179833587 179833782 196 + 2.471 2.451 -0.069
ENSG00000161011 E035 0.0000000       5 179836436 179836470 35 +      
ENSG00000161011 E036 0.0000000       5 179836471 179838078 1608 +      

Help

Please Click HERE to learn more details about the results from DEXseq.