ENSG00000161091

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000355415 ENSG00000161091 No_inf pgKDN_inf MFSD12 protein_coding protein_coding 147.1227 77.48968 156.9244 0.2208152 3.224119 1.017899 90.990878 35.604877 101.867240 0.7903852 3.254224 1.51627985 0.58773333 0.459425 0.648775 0.189350 4.515947e-06 4.515947e-06 FALSE TRUE
ENST00000585788 ENSG00000161091 No_inf pgKDN_inf MFSD12 protein_coding retained_intron 147.1227 77.48968 156.9244 0.2208152 3.224119 1.017899 15.265686 15.944247 12.408661 1.2578027 1.081587 -0.36143092 0.12307500 0.205650 0.079300 -0.126350 1.995990e-03 4.515947e-06 FALSE FALSE
ENST00000589157 ENSG00000161091 No_inf pgKDN_inf MFSD12 protein_coding retained_intron 147.1227 77.48968 156.9244 0.2208152 3.224119 1.017899 10.879825 9.837408 9.416353 0.4087138 1.471026 -0.06304439 0.08376667 0.126975 0.059575 -0.067400 8.902871e-02 4.515947e-06   FALSE
ENST00000615073 ENSG00000161091 No_inf pgKDN_inf MFSD12 protein_coding protein_coding 147.1227 77.48968 156.9244 0.2208152 3.224119 1.017899 14.384007 3.597671 17.870193 1.3922910 1.180293 2.30922244 0.08845000 0.046375 0.114075 0.067700 4.101829e-01 4.515947e-06 FALSE TRUE
MSTRG.14293.8 ENSG00000161091 No_inf pgKDN_inf MFSD12 protein_coding   147.1227 77.48968 156.9244 0.2208152 3.224119 1.017899 7.167899 4.957807 7.401859 0.6065050 1.508031 0.57722641 0.05196667 0.064025 0.047800 -0.016225 8.245448e-01 4.515947e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000161091 E001 0.000000       19 3538261 3538274 14 -      
ENSG00000161091 E002 28.600971 0.0004899253 7.463746e-03 6.598093e-02 19 3538275 3538649 375 - 1.382 1.553 0.588
ENSG00000161091 E003 25.223089 0.0052262253 9.464672e-03 7.760552e-02 19 3538650 3538719 70 - 1.321 1.512 0.661
ENSG00000161091 E004 21.808454 0.0063134580 1.673069e-02 1.127873e-01 19 3538720 3538756 37 - 1.261 1.450 0.658
ENSG00000161091 E005 92.623405 0.0096702160 9.280246e-22 2.997131e-19 19 3538757 3540043 1287 - 1.712 2.209 1.668
ENSG00000161091 E006 13.673253 0.0011092770 1.202955e-07 6.894813e-06 19 3542776 3542977 202 - 0.948 1.379 1.542
ENSG00000161091 E007 12.609391 0.0021647974 6.543465e-04 1.075633e-02 19 3542978 3543382 405 - 0.987 1.285 1.068
ENSG00000161091 E008 1.225572 0.0102951794 2.706392e-01 5.643181e-01 19 3544076 3544198 123 - 0.264 0.446 1.096
ENSG00000161091 E009 0.000000       19 3544199 3544199 1 -      
ENSG00000161091 E010 0.000000       19 3544200 3544307 108 -      
ENSG00000161091 E011 0.000000       19 3544308 3544309 2 -      
ENSG00000161091 E012 0.000000       19 3544310 3544354 45 -      
ENSG00000161091 E013 0.000000       19 3544355 3544356 2 -      
ENSG00000161091 E014 10.551696 0.0013162155 4.509878e-01 7.241746e-01 19 3544357 3544675 319 - 1.009 1.095 0.315
ENSG00000161091 E015 40.726301 0.0003496647 7.329451e-01 8.938129e-01 19 3544676 3544732 57 - 1.595 1.598 0.012
ENSG00000161091 E016 2.685086 0.0053508583 2.280779e-01 5.165297e-01 19 3544733 3544808 76 - 0.478 0.661 0.833
ENSG00000161091 E017 62.224419 0.0002509882 7.119053e-02 2.703556e-01 19 3544809 3544833 25 - 1.793 1.741 -0.177
ENSG00000161091 E018 97.787402 0.0001810027 1.742733e-01 4.479462e-01 19 3544834 3544939 106 - 1.977 1.955 -0.075
ENSG00000161091 E019 74.722807 0.0002530285 2.663151e-01 5.597671e-01 19 3546074 3546168 95 - 1.861 1.841 -0.068
ENSG00000161091 E020 103.993149 0.0001665250 5.311319e-02 2.292603e-01 19 3546255 3546425 171 - 2.009 1.970 -0.131
ENSG00000161091 E021 41.240415 0.0003831731 9.303530e-01 9.796497e-01 19 3547272 3547290 19 - 1.593 1.617 0.084
ENSG00000161091 E022 49.316868 0.0003703659 7.263824e-01 8.904754e-01 19 3547291 3547326 36 - 1.675 1.680 0.016
ENSG00000161091 E023 53.792295 0.0004382286 6.909157e-02 2.656012e-01 19 3547327 3547364 38 - 1.733 1.674 -0.201
ENSG00000161091 E024 63.906777 0.0002577099 4.239111e-02 2.005897e-01 19 3547455 3547521 67 - 1.807 1.746 -0.205
ENSG00000161091 E025 41.831796 0.0004236914 1.921115e-03 2.480570e-02 19 3547522 3547547 26 - 1.649 1.512 -0.467
ENSG00000161091 E026 56.688629 0.0014968786 7.632562e-03 6.692482e-02 19 3547848 3547918 71 - 1.768 1.667 -0.341
ENSG00000161091 E027 72.633625 0.0005847998 7.746861e-03 6.765207e-02 19 3547919 3548030 112 - 1.868 1.786 -0.276
ENSG00000161091 E028 66.987616 0.0002441644 7.093587e-03 6.361763e-02 19 3548123 3548267 145 - 1.834 1.749 -0.288
ENSG00000161091 E029 25.545088 0.0005899319 1.109534e-01 3.496531e-01 19 3550984 3550987 4 - 1.425 1.345 -0.278
ENSG00000161091 E030 89.695708 0.0002991673 5.130667e-03 5.058159e-02 19 3550988 3551194 207 - 1.956 1.882 -0.250
ENSG00000161091 E031 29.980227 0.0004829340 2.836595e-02 1.575754e-01 19 3557106 3557132 27 - 1.500 1.391 -0.375
ENSG00000161091 E032 84.093608 0.0002059118 6.288007e-02 2.521280e-01 19 3557133 3557586 454 - 1.919 1.876 -0.147
ENSG00000161091 E033 0.000000       19 3567145 3567242 98 -      
ENSG00000161091 E034 0.761403 0.0132524456 6.382966e-04 1.053424e-02 19 3571572 3571655 84 - 0.000 0.498 11.951
ENSG00000161091 E035 0.000000       19 3572861 3573021 161 -      
ENSG00000161091 E036 1.114522 0.0111343580 4.099917e-02 1.965407e-01 19 3573556 3573738 183 - 0.177 0.498 2.096
ENSG00000161091 E037 0.000000       19 3573739 3573851 113 -      
ENSG00000161091 E038 0.000000       19 3574243 3574290 48 -      

Help

Please Click HERE to learn more details about the results from DEXseq.