ENSG00000161638

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000293379 ENSG00000161638 No_inf pgKDN_inf ITGA5 protein_coding protein_coding 355.2047 203.2532 397.8439 4.555456 3.079469 0.9688899 214.2486 103.20898 258.951554 1.545290 2.136057 1.3270296 0.58796667 0.508275 0.651050 0.142775 2.225179e-06 2.225179e-06 FALSE TRUE
ENST00000547197 ENSG00000161638 No_inf pgKDN_inf ITGA5 protein_coding protein_coding 355.2047 203.2532 397.8439 4.555456 3.079469 0.9688899 105.8583 60.69034 117.027837 3.076109 4.149982 0.9471985 0.29787500 0.298925 0.294050 -0.004875 9.924962e-01 2.225179e-06 FALSE FALSE
ENST00000552431 ENSG00000161638 No_inf pgKDN_inf ITGA5 protein_coding retained_intron 355.2047 203.2532 397.8439 4.555456 3.079469 0.9688899 14.6388 15.04632 9.134099 3.299406 1.361991 -0.7194558 0.04625833 0.073275 0.022925 -0.050350 2.422122e-02 2.225179e-06   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000161638 E001 680.9752551 2.169724e-04 6.508463e-02 2.570152e-01 12 54395261 54395894 634 - 2.803 2.826 0.077
ENSG00000161638 E002 619.3917032 3.677804e-04 2.892655e-01 5.829409e-01 12 54395895 54396221 327 - 2.765 2.779 0.048
ENSG00000161638 E003 325.3912720 6.827040e-05 1.381597e-01 3.955327e-01 12 54396222 54396376 155 - 2.482 2.507 0.084
ENSG00000161638 E004 2.1136684 8.058952e-03 1.584424e-03 2.133158e-02 12 54397271 54397364 94 - 0.267 0.718 2.314
ENSG00000161638 E005 118.4470833 1.368430e-04 4.664631e-01 7.351476e-01 12 54397365 54397365 1 - 2.047 2.068 0.069
ENSG00000161638 E006 285.8117541 8.174177e-05 9.089128e-02 3.130687e-01 12 54397366 54397487 122 - 2.424 2.455 0.103
ENSG00000161638 E007 269.4652556 1.170277e-04 2.065526e-02 1.294620e-01 12 54398597 54398698 102 - 2.394 2.438 0.147
ENSG00000161638 E008 1.1074686 1.765204e-01 2.406862e-01 5.298943e-01 12 54398699 54398823 125 - 0.225 0.441 1.373
ENSG00000161638 E009 260.6827376 7.842288e-05 7.211165e-02 2.723213e-01 12 54399645 54399758 114 - 2.383 2.417 0.115
ENSG00000161638 E010 6.2047629 2.314545e-03 4.157968e-07 2.093892e-05 12 54399759 54399863 105 - 0.571 1.113 2.139
ENSG00000161638 E011 197.7865852 1.039877e-04 8.399766e-01 9.425882e-01 12 54399864 54399947 84 - 2.277 2.272 -0.018
ENSG00000161638 E012 44.1192708 5.692968e-04 2.399358e-37 1.960712e-34 12 54399948 54400845 898 - 1.330 1.925 2.027
ENSG00000161638 E013 252.3918977 6.633882e-04 1.496328e-01 4.119811e-01 12 54400846 54400995 150 - 2.370 2.401 0.104
ENSG00000161638 E014 190.2087070 1.131400e-04 1.303114e-01 3.829806e-01 12 54401373 54401478 106 - 2.247 2.281 0.114
ENSG00000161638 E015 1.1177903 7.464898e-02 4.988618e-02 2.203753e-01 12 54401560 54401584 25 - 0.179 0.493 2.051
ENSG00000161638 E016 193.0635691 4.330255e-03 8.729804e-01 9.566407e-01 12 54401585 54401665 81 - 2.267 2.262 -0.016
ENSG00000161638 E017 2.3634178 1.658790e-02 4.012026e-04 7.322661e-03 12 54401666 54401775 110 - 0.267 0.773 2.537
ENSG00000161638 E018 191.8571611 1.314206e-03 1.601124e-01 4.277330e-01 12 54401776 54401855 80 - 2.275 2.236 -0.131
ENSG00000161638 E019 184.3421901 7.092037e-04 1.842756e-02 1.200908e-01 12 54402001 54402080 80 - 2.266 2.203 -0.209
ENSG00000161638 E020 109.7915028 1.491222e-04 3.771671e-01 6.641729e-01 12 54402081 54402093 13 - 2.031 2.003 -0.094
ENSG00000161638 E021 0.4877773 1.065416e-01 4.850805e-01   12 54402094 54402179 86 - 0.127 0.232 1.052
ENSG00000161638 E022 261.2334278 1.889597e-04 8.059316e-01 9.281010e-01 12 54402180 54402330 151 - 2.398 2.392 -0.019
ENSG00000161638 E023 143.1853070 1.173461e-04 8.958994e-01 9.657809e-01 12 54402983 54403050 68 - 2.135 2.138 0.009
ENSG00000161638 E024 0.8612261 1.831489e-02 1.876840e-01 4.658330e-01 12 54403051 54403172 122 - 0.179 0.382 1.466
ENSG00000161638 E025 175.0067115 4.859738e-04 2.201127e-01 5.068983e-01 12 54403187 54403324 138 - 2.234 2.201 -0.109
ENSG00000161638 E026 0.8446693 1.255645e-02 8.238040e-01 9.360718e-01 12 54403325 54403624 300 - 0.267 0.232 -0.271
ENSG00000161638 E027 69.2632615 1.320195e-03 1.916225e-01 4.712707e-01 12 54403625 54403631 7 - 1.842 1.787 -0.186
ENSG00000161638 E028 186.9519421 1.100498e-04 6.674662e-04 1.093201e-02 12 54403632 54403779 148 - 2.278 2.195 -0.276
ENSG00000161638 E029 57.4874725 3.267026e-03 8.591599e-02 3.034772e-01 12 54403911 54403915 5 - 1.772 1.686 -0.290
ENSG00000161638 E030 94.6320795 1.954814e-03 4.254682e-02 2.010267e-01 12 54403916 54403966 51 - 1.983 1.905 -0.264
ENSG00000161638 E031 0.7246452 3.328426e-02 9.658294e-01 9.929858e-01 12 54403967 54404144 178 - 0.225 0.232 0.051
ENSG00000161638 E032 125.3036025 1.520100e-04 1.751201e-02 1.160738e-01 12 54404145 54404246 102 - 2.101 2.031 -0.236
ENSG00000161638 E033 2.8308941 5.203529e-03 1.971546e-02 1.257651e-01 12 54404247 54404429 183 - 0.431 0.747 1.430
ENSG00000161638 E034 77.7195033 2.225752e-04 1.232014e-01 3.715468e-01 12 54404430 54404475 46 - 1.892 1.834 -0.195
ENSG00000161638 E035 2.8753913 1.348307e-02 1.402703e-05 4.573967e-04 12 54404476 54404702 227 - 0.267 0.866 2.899
ENSG00000161638 E036 77.7365321 1.437369e-03 2.041915e-02 1.285949e-01 12 54404703 54404770 68 - 1.903 1.809 -0.318
ENSG00000161638 E037 89.2266148 2.366470e-03 6.341930e-03 5.877073e-02 12 54404771 54404894 124 - 1.968 1.856 -0.375
ENSG00000161638 E038 48.5258929 1.233404e-02 1.495225e-01 4.118437e-01 12 54405166 54405193 28 - 1.704 1.603 -0.344
ENSG00000161638 E039 127.7320280 3.729063e-03 3.288922e-02 1.720344e-01 12 54405194 54405374 181 - 2.114 2.030 -0.283
ENSG00000161638 E040 68.6837456 1.155737e-03 1.388070e-01 3.961906e-01 12 54405664 54405716 53 - 1.800 1.858 0.198
ENSG00000161638 E041 77.0101365 2.174745e-04 8.718013e-01 9.560742e-01 12 54405870 54405926 57 - 1.868 1.873 0.017
ENSG00000161638 E042 4.2016611 3.432131e-03 5.730105e-04 9.709314e-03 12 54405927 54406116 190 - 0.507 0.924 1.743
ENSG00000161638 E043 61.1713019 2.455083e-04 2.250603e-01 5.126881e-01 12 54407649 54407692 44 - 1.788 1.737 -0.172
ENSG00000161638 E044 62.2350126 2.216621e-04 7.492939e-01 9.011778e-01 12 54407832 54407876 45 - 1.783 1.769 -0.047
ENSG00000161638 E045 95.8588585 3.322557e-03 9.226981e-01 9.762398e-01 12 54408110 54408235 126 - 1.965 1.960 -0.018
ENSG00000161638 E046 61.0663508 6.748598e-04 2.465390e-01 5.371550e-01 12 54408756 54408801 46 - 1.787 1.737 -0.168
ENSG00000161638 E047 60.6000631 2.313936e-04 2.868380e-01 5.802590e-01 12 54408893 54408954 62 - 1.782 1.737 -0.152
ENSG00000161638 E048 89.1395544 3.566676e-03 8.115924e-02 2.927138e-01 12 54409232 54409352 121 - 1.956 1.881 -0.253
ENSG00000161638 E049 35.0195921 4.218290e-03 1.868899e-02 1.213401e-01 12 54409485 54409597 113 - 1.579 1.433 -0.501
ENSG00000161638 E050 35.2109297 1.069338e-03 1.807505e-01 4.564607e-01 12 54411834 54411907 74 - 1.561 1.486 -0.257
ENSG00000161638 E051 50.7207420 1.083015e-03 3.932963e-01 6.781993e-01 12 54411908 54411964 57 - 1.705 1.664 -0.139
ENSG00000161638 E052 2.2402713 6.318499e-03 6.721645e-04 1.099344e-02 12 54412311 54412516 206 - 0.267 0.747 2.430
ENSG00000161638 E053 2.3329798 3.666298e-02 9.534021e-02 3.214603e-01 12 54413145 54413428 284 - 0.403 0.656 1.203
ENSG00000161638 E054 78.8274555 1.967140e-04 2.023822e-01 4.848102e-01 12 54418981 54419266 286 - 1.895 1.848 -0.160

Help

Please Click HERE to learn more details about the results from DEXseq.