ENSG00000161692

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000393547 ENSG00000161692 No_inf pgKDN_inf DBF4B protein_coding protein_coding 9.15506 6.016111 17.15424 0.214936 12.76659 1.510107 0.2734471 0.0000000 0.82034124 0.0000000 0.29793859 6.3756325 0.05792500 0.000000 0.173775 0.173775 0.296648646 0.001958971 FALSE TRUE
ENST00000526924 ENSG00000161692 No_inf pgKDN_inf DBF4B protein_coding nonsense_mediated_decay 9.15506 6.016111 17.15424 0.214936 12.76659 1.510107 0.6525739 0.0000000 0.96977850 0.0000000 0.57964671 6.6143837 0.14623333 0.000000 0.220100 0.220100 0.687073627 0.001958971 FALSE TRUE
ENST00000527862 ENSG00000161692 No_inf pgKDN_inf DBF4B protein_coding retained_intron 9.15506 6.016111 17.15424 0.214936 12.76659 1.510107 1.4112960 2.2018057 1.12914839 0.1608025 0.47968509 -0.9572690 0.25605833 0.369425 0.182500 -0.186925 0.469861382 0.001958971 FALSE TRUE
ENST00000528353 ENSG00000161692 No_inf pgKDN_inf DBF4B protein_coding retained_intron 9.15506 6.016111 17.15424 0.214936 12.76659 1.510107 0.4752058 0.7201085 0.56153630 0.1873816 0.22050497 -0.3532658 0.09203333 0.117800 0.127275 0.009475 0.958424055 0.001958971 FALSE FALSE
MSTRG.12764.13 ENSG00000161692 No_inf pgKDN_inf DBF4B protein_coding   9.15506 6.016111 17.15424 0.214936 12.76659 1.510107 4.2966830 0.0000000 12.89004904 0.0000000 12.89004904 10.3331608 0.07749167 0.000000 0.232475 0.232475 0.877498794 0.001958971   FALSE
MSTRG.12764.2 ENSG00000161692 No_inf pgKDN_inf DBF4B protein_coding   9.15506 6.016111 17.15424 0.214936 12.76659 1.510107 1.1009839 1.5660716 0.34738704 0.1722041 0.34738704 -2.1407738 0.19844167 0.258925 0.006275 -0.252650 0.001958971 0.001958971 FALSE TRUE
MSTRG.12764.8 ENSG00000161692 No_inf pgKDN_inf DBF4B protein_coding   9.15506 6.016111 17.15424 0.214936 12.76659 1.510107 0.6453347 1.2790745 0.08726354 0.1906558 0.08726354 -3.7282928 0.12088333 0.211750 0.018075 -0.193675 0.014315901 0.001958971 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000161692 E001 0.2346346 0.0162959482 9.723422e-02   17 44708608 44708655 48 + 0.219 0.000 -11.803
ENSG00000161692 E002 0.3617709 0.0171049692 2.824716e-01   17 44708656 44708664 9 + 0.219 0.073 -1.842
ENSG00000161692 E003 0.6065379 0.1434260058 2.996019e-01 5.924984e-01 17 44708665 44708697 33 + 0.297 0.135 -1.426
ENSG00000161692 E004 0.9705149 0.0124558443 1.259882e-01 3.763109e-01 17 44708698 44708727 30 + 0.421 0.190 -1.579
ENSG00000161692 E005 2.5068449 0.0057385923 2.096163e-06 8.839283e-05 17 44708728 44708839 112 + 0.839 0.190 -3.427
ENSG00000161692 E006 0.0000000       17 44708844 44708845 2 +      
ENSG00000161692 E007 0.1265070 0.0124053987 1.000000e+00   17 44708846 44708861 16 + 0.000 0.073 11.301
ENSG00000161692 E008 0.7607737 0.0141773159 5.165013e-02 2.254713e-01 17 44708862 44708938 77 + 0.000 0.322 13.511
ENSG00000161692 E009 2.4406681 0.0060407616 7.947503e-02 2.891785e-01 17 44709304 44709366 63 + 0.663 0.422 -1.131
ENSG00000161692 E010 2.8475672 0.0053171660 9.277603e-01 9.785977e-01 17 44722880 44723022 143 + 0.559 0.573 0.065
ENSG00000161692 E011 3.0684229 0.0048272021 2.070674e-01 4.906806e-01 17 44729905 44730096 192 + 0.693 0.528 -0.726
ENSG00000161692 E012 1.3343631 0.0096698631 6.136472e-02 2.487893e-01 17 44730965 44731015 51 + 0.518 0.238 -1.649
ENSG00000161692 E013 2.9775699 0.0101965863 8.104176e-01 9.301186e-01 17 44731016 44731504 489 + 0.559 0.594 0.158
ENSG00000161692 E014 5.9870890 0.0119040785 1.206366e-01 3.674159e-01 17 44731505 44732177 673 + 0.693 0.880 0.743
ENSG00000161692 E015 1.5875668 0.0503509473 2.083922e-01 4.923525e-01 17 44732178 44732265 88 + 0.518 0.322 -1.064
ENSG00000161692 E016 1.9959215 0.0366539085 3.813570e-01 6.678175e-01 17 44732266 44732877 612 + 0.364 0.504 0.743
ENSG00000161692 E017 2.7410136 0.0057854518 3.985809e-01 6.824248e-01 17 44733659 44734089 431 + 0.472 0.594 0.573
ENSG00000161692 E018 2.1303559 0.0070685337 1.007423e-01 3.313274e-01 17 44734090 44734163 74 + 0.297 0.551 1.380
ENSG00000161692 E019 1.4956158 0.0392709236 4.437579e-01 7.184357e-01 17 44736830 44736836 7 + 0.297 0.422 0.743
ENSG00000161692 E020 2.6193241 0.0057453973 2.403095e-01 5.294898e-01 17 44736837 44736866 30 + 0.421 0.594 0.836
ENSG00000161692 E021 2.3471758 0.0061993091 9.161326e-01 9.737053e-01 17 44738379 44738424 46 + 0.518 0.504 -0.064
ENSG00000161692 E022 1.2245364 0.0112353598 3.576364e-01 6.472087e-01 17 44741336 44741400 65 + 0.421 0.282 -0.842
ENSG00000161692 E023 2.4958666 0.0081466115 3.094365e-01 6.027860e-01 17 44741401 44741452 52 + 0.421 0.573 0.743
ENSG00000161692 E024 4.4671390 0.0053076199 7.659064e-01 9.090536e-01 17 44747083 44747191 109 + 0.693 0.731 0.158
ENSG00000161692 E025 4.9625372 0.0030591052 6.649216e-01 8.606994e-01 17 44747391 44747515 125 + 0.721 0.774 0.213
ENSG00000161692 E026 2.9643840 0.0066265879 8.534399e-01 9.483216e-01 17 44748341 44748465 125 + 0.597 0.573 -0.105
ENSG00000161692 E027 36.1102541 0.0005700756 5.741670e-01 8.092595e-01 17 44748466 44750476 2011 + 1.561 1.540 -0.073
ENSG00000161692 E028 0.6339197 0.0289073143 9.062688e-02 3.126836e-01 17 44750595 44750677 83 + 0.000 0.282 13.289
ENSG00000161692 E029 6.3938974 0.0021966969 3.721643e-03 4.037882e-02 17 44750678 44751939 1262 + 0.597 0.938 1.380
ENSG00000161692 E030 0.7438075 0.0154708165 9.041551e-01 9.691496e-01 17 44751940 44752264 325 + 0.219 0.238 0.158

Help

Please Click HERE to learn more details about the results from DEXseq.