ENSG00000161791

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000335154 ENSG00000161791 No_inf pgKDN_inf FMNL3 protein_coding protein_coding 27.99898 17.30197 32.44478 1.472235 0.9663934 0.9066612 6.664136 1.1491939 9.1330721 1.1491939 0.2137628 2.97955704 0.21041667 0.066025 0.282225 0.216200 4.538461e-02 7.825591e-08 FALSE TRUE
ENST00000352151 ENSG00000161791 No_inf pgKDN_inf FMNL3 protein_coding protein_coding 27.99898 17.30197 32.44478 1.472235 0.9663934 0.9066612 7.800993 1.9825330 9.7831870 1.2302723 0.8543017 2.29717480 0.25262500 0.109925 0.303875 0.193950 3.311173e-01 7.825591e-08 FALSE TRUE
ENST00000549137 ENSG00000161791 No_inf pgKDN_inf FMNL3 protein_coding retained_intron 27.99898 17.30197 32.44478 1.472235 0.9663934 0.9066612 3.476488 2.4567084 4.7086052 1.0885305 1.5705537 0.93577328 0.12077500 0.129825 0.141400 0.011575 1.000000e+00 7.825591e-08 FALSE TRUE
MSTRG.6475.1 ENSG00000161791 No_inf pgKDN_inf FMNL3 protein_coding   27.99898 17.30197 32.44478 1.472235 0.9663934 0.9066612 1.733301 5.1999036 0.0000000 1.1748558 0.0000000 -9.02511286 0.10372500 0.311175 0.000000 -0.311175 7.825591e-08 7.825591e-08 FALSE TRUE
MSTRG.6475.11 ENSG00000161791 No_inf pgKDN_inf FMNL3 protein_coding   27.99898 17.30197 32.44478 1.472235 0.9663934 0.9066612 2.002697 1.0051410 2.4594704 1.0051410 1.4372454 1.28252162 0.06958333 0.051750 0.078925 0.027175 8.423181e-01 7.825591e-08 FALSE TRUE
MSTRG.6475.12 ENSG00000161791 No_inf pgKDN_inf FMNL3 protein_coding   27.99898 17.30197 32.44478 1.472235 0.9663934 0.9066612 1.915376 0.7098777 0.7333714 0.7098777 0.7333714 0.04633136 0.06107500 0.036550 0.022700 -0.013850 9.624994e-01 7.825591e-08 FALSE TRUE
MSTRG.6475.5 ENSG00000161791 No_inf pgKDN_inf FMNL3 protein_coding   27.99898 17.30197 32.44478 1.472235 0.9663934 0.9066612 0.572386 0.8626132 0.0000000 0.8626132 0.0000000 -6.44727047 0.02975000 0.065825 0.000000 -0.065825 8.270679e-01 7.825591e-08 FALSE TRUE
MSTRG.6475.6 ENSG00000161791 No_inf pgKDN_inf FMNL3 protein_coding   27.99898 17.30197 32.44478 1.472235 0.9663934 0.9066612 2.758800 3.3492618 4.9271370 1.2921934 1.8829429 0.55553046 0.11625833 0.198625 0.150150 -0.048475 9.451747e-01 7.825591e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000161791 E001 0.4804741 0.0153511445 0.5785518111   12 49636499 49636518 20 - 0.201 0.116 -0.939
ENSG00000161791 E002 36.9801167 0.0003926116 0.0002647098 0.005250775 12 49636519 49637941 1423 - 1.490 1.669 0.608
ENSG00000161791 E003 30.9511975 0.0004919291 0.2077949709 0.491474007 12 49637942 49638520 579 - 1.468 1.536 0.234
ENSG00000161791 E004 27.0458367 0.0039194039 0.2939532451 0.587383732 12 49638521 49639002 482 - 1.412 1.478 0.227
ENSG00000161791 E005 134.6020245 0.0024145447 0.0032152003 0.036361630 12 49639003 49644739 5737 - 2.086 2.176 0.299
ENSG00000161791 E006 7.5831413 0.0018155217 0.1395982383 0.397292564 12 49644740 49644919 180 - 0.861 1.008 0.553
ENSG00000161791 E007 1.6962923 0.0080034417 0.7991958849 0.924667732 12 49644920 49644930 11 - 0.441 0.403 -0.202
ENSG00000161791 E008 2.5366522 0.0475016006 0.6072868639 0.829053325 12 49644931 49644952 22 - 0.573 0.497 -0.354
ENSG00000161791 E009 1.9462550 0.0275079031 0.7179962601 0.886507264 12 49644953 49644959 7 - 0.441 0.497 0.284
ENSG00000161791 E010 10.4476061 0.0273535559 0.9495994258 0.986887884 12 49644960 49645093 134 - 1.048 1.057 0.033
ENSG00000161791 E011 83.1233278 0.0001891486 0.8137209230 0.931871503 12 49645094 49645697 604 - 1.914 1.923 0.029
ENSG00000161791 E012 40.9705281 0.0003506836 0.2138922602 0.499182115 12 49645698 49645903 206 - 1.638 1.580 -0.197
ENSG00000161791 E013 9.1283969 0.0033635761 0.6909081859 0.873149418 12 49646639 49646753 115 - 0.983 1.021 0.141
ENSG00000161791 E014 37.6544734 0.0004254576 0.0890446820 0.309621293 12 49646886 49647009 124 - 1.612 1.528 -0.285
ENSG00000161791 E015 31.2751769 0.0007051846 0.2640256170 0.557120614 12 49647276 49647368 93 - 1.525 1.465 -0.205
ENSG00000161791 E016 26.1103467 0.0010252159 0.7872975292 0.918377562 12 49647703 49647801 99 - 1.432 1.417 -0.052
ENSG00000161791 E017 8.2901339 0.0329743374 0.4945190146 0.755960505 12 49647802 49647804 3 - 0.926 1.008 0.305
ENSG00000161791 E018 34.3773543 0.0003936267 0.9505687342 0.987384668 12 49648193 49648353 161 - 1.542 1.540 -0.007
ENSG00000161791 E019 29.8996828 0.0005802786 0.0624704326 0.251138962 12 49649029 49649158 130 - 1.438 1.540 0.351
ENSG00000161791 E020 18.9397077 0.0007994819 0.0624415200 0.251134990 12 49649259 49649339 81 - 1.237 1.363 0.441
ENSG00000161791 E021 14.3870011 0.0022343582 0.2296264118 0.518247380 12 49649470 49649538 69 - 1.216 1.122 -0.336
ENSG00000161791 E022 32.1490814 0.0004449403 0.0158679902 0.109175173 12 49649691 49649925 235 - 1.561 1.432 -0.444
ENSG00000161791 E023 23.1266446 0.0005963183 0.1518325520 0.415450097 12 49650676 49650878 203 - 1.409 1.320 -0.309
ENSG00000161791 E024 19.1319790 0.0177097162 0.2492310460 0.540159709 12 49651168 49651292 125 - 1.333 1.236 -0.341
ENSG00000161791 E025 10.5934914 0.0013333786 0.6594039476 0.857880464 12 49651382 49651450 69 - 1.041 1.080 0.144
ENSG00000161791 E026 43.2025683 0.0019047837 0.0693569925 0.266223047 12 49651933 49652209 277 - 1.672 1.584 -0.300
ENSG00000161791 E027 12.5768212 0.0119602016 0.3204712177 0.613375019 12 49652210 49652212 3 - 1.161 1.069 -0.333
ENSG00000161791 E028 0.4815466 0.0301533999 0.5816732582   12 49652213 49652242 30 - 0.201 0.116 -0.939
ENSG00000161791 E029 24.5161035 0.0021715111 0.7952949956 0.922216527 12 49653226 49653327 102 - 1.406 1.391 -0.053
ENSG00000161791 E030 26.9570845 0.0005682944 0.9245020695 0.977150746 12 49653725 49653871 147 - 1.441 1.437 -0.015
ENSG00000161791 E031 8.0236286 0.0157888949 0.7818808528 0.916099842 12 49653872 49653874 3 - 0.936 0.967 0.116
ENSG00000161791 E032 17.0024121 0.0113782133 0.0303950690 0.164031184 12 49654192 49654302 111 - 1.313 1.132 -0.640
ENSG00000161791 E033 13.3939685 0.0280899799 0.0984530351 0.327371516 12 49654910 49654984 75 - 1.211 1.045 -0.596
ENSG00000161791 E034 15.4550593 0.0091683207 0.8018698173 0.926102464 12 49656404 49656497 94 - 1.201 1.221 0.070
ENSG00000161791 E035 16.3172337 0.0009830005 0.5182510560 0.773461521 12 49656823 49656899 77 - 1.211 1.259 0.168
ENSG00000161791 E036 15.4930674 0.0053877131 0.2768383372 0.570248440 12 49657082 49657190 109 - 1.173 1.259 0.304
ENSG00000161791 E037 7.3900567 0.0187247041 0.0001231528 0.002815651 12 49658442 49658594 153 - 1.056 0.575 -1.911
ENSG00000161791 E038 1.0071799 0.0853687797 0.0088496658 0.074091567 12 49661735 49661965 231 - 0.078 0.497 3.454
ENSG00000161791 E039 14.4659081 0.0011694033 0.9195998501 0.974921015 12 49661966 49662049 84 - 1.179 1.187 0.031
ENSG00000161791 E040 0.2442663 0.0165741539 0.7293235197   12 49662050 49662191 142 - 0.078 0.116 0.646
ENSG00000161791 E041 11.4547039 0.0012941738 0.4910326634 0.753490240 12 49665832 49665908 77 - 1.063 1.122 0.213
ENSG00000161791 E042 6.0912658 0.0024614363 0.6742982316 0.865013724 12 49666127 49666158 32 - 0.824 0.871 0.180
ENSG00000161791 E043 8.8681233 0.0018320274 0.9037589067 0.969069060 12 49666159 49666207 49 - 0.991 0.981 -0.038
ENSG00000161791 E044 10.0329176 0.0017308592 0.2229656693 0.510395586 12 49668471 49668554 84 - 1.078 0.967 -0.406
ENSG00000161791 E045 0.3543453 0.0157825006 0.2221233994   12 49688445 49688626 182 - 0.201 0.000 -9.590
ENSG00000161791 E046 16.6350035 0.0008862463 0.0139359723 0.099711161 12 49707055 49707463 409 - 1.305 1.122 -0.647
ENSG00000161791 E047 0.0000000       12 49707934 49708165 232 -      

Help

Please Click HERE to learn more details about the results from DEXseq.