ENSG00000161904

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000293760 ENSG00000161904 No_inf pgKDN_inf LEMD2 protein_coding protein_coding 49.02273 58.18844 41.74259 1.662465 2.102488 -0.4791147 20.497063 11.685557 25.027851 0.7494857 2.2972334 1.0981502 0.44345000 0.200500 0.603925 0.403425 7.883836e-06 6.957915e-14 FALSE TRUE
ENST00000421671 ENSG00000161904 No_inf pgKDN_inf LEMD2 protein_coding nonsense_mediated_decay 49.02273 58.18844 41.74259 1.662465 2.102488 -0.4791147 8.469488 7.908586 6.893537 1.3331465 3.0361734 -0.1979071 0.17485833 0.137275 0.161650 0.024375 9.880477e-01 6.957915e-14 FALSE TRUE
ENST00000506578 ENSG00000161904 No_inf pgKDN_inf LEMD2 protein_coding protein_coding 49.02273 58.18844 41.74259 1.662465 2.102488 -0.4791147 3.601131 10.803394 0.000000 1.1899281 0.0000000 -10.0786036 0.06150833 0.184525 0.000000 -0.184525 6.957915e-14 6.957915e-14   FALSE
ENST00000508327 ENSG00000161904 No_inf pgKDN_inf LEMD2 protein_coding protein_coding 49.02273 58.18844 41.74259 1.662465 2.102488 -0.4791147 6.443213 11.141312 4.451581 0.3477230 0.3300679 -1.3215864 0.12553333 0.191800 0.106550 -0.085250 2.156490e-01 6.957915e-14 FALSE TRUE
ENST00000512368 ENSG00000161904 No_inf pgKDN_inf LEMD2 protein_coding retained_intron 49.02273 58.18844 41.74259 1.662465 2.102488 -0.4791147 3.068713 5.864546 1.287837 1.9598569 0.7545873 -2.1783682 0.05862500 0.101900 0.030950 -0.070950 6.871679e-01 6.957915e-14 FALSE FALSE
MSTRG.24558.2 ENSG00000161904 No_inf pgKDN_inf LEMD2 protein_coding   49.02273 58.18844 41.74259 1.662465 2.102488 -0.4791147 3.184924 3.192403 2.038955 0.3681420 0.5796735 -0.6442665 0.06595833 0.054825 0.050875 -0.003950 9.263288e-01 6.957915e-14 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000161904 E001 0.1271363 0.0123330558 7.072573e-01   6 33771202 33771212 11 - 0.000 0.084 7.924
ENSG00000161904 E002 1.1156222 0.0115600351 5.529584e-01 7.963031e-01 6 33771213 33771221 9 - 0.265 0.358 0.607
ENSG00000161904 E003 21.3548111 0.0006743098 2.929966e-01 5.866494e-01 6 33771222 33771431 210 - 1.380 1.315 -0.227
ENSG00000161904 E004 56.1219231 0.0014728211 2.909178e-01 5.844627e-01 6 33771432 33771658 227 - 1.775 1.732 -0.146
ENSG00000161904 E005 23.6228861 0.0010145022 9.857398e-01 9.990789e-01 6 33771659 33771696 38 - 1.385 1.385 0.000
ENSG00000161904 E006 126.5186171 0.0001533009 8.293868e-03 7.083476e-02 6 33771697 33772324 628 - 2.137 2.071 -0.222
ENSG00000161904 E007 111.5561692 0.0028961691 2.514662e-01 5.426023e-01 6 33772325 33772766 442 - 2.066 2.029 -0.125
ENSG00000161904 E008 23.4127206 0.0011383034 1.288408e-01 3.807820e-01 6 33772767 33772775 9 - 1.433 1.341 -0.317
ENSG00000161904 E009 22.2003315 0.0026847348 2.027925e-01 4.853521e-01 6 33772776 33772778 3 - 1.405 1.324 -0.281
ENSG00000161904 E010 2.3654563 0.0059780877 1.322089e-01 3.859362e-01 6 33776614 33776953 340 - 0.381 0.601 1.093
ENSG00000161904 E011 36.9866930 0.0004207740 4.070450e-01 6.895830e-01 6 33776954 33777011 58 - 1.596 1.557 -0.133
ENSG00000161904 E012 25.4768516 0.0043035093 9.620484e-01 9.917057e-01 6 33777012 33777034 23 - 1.414 1.418 0.014
ENSG00000161904 E013 23.3026713 0.0130038962 4.999830e-01 7.601921e-01 6 33777035 33777056 22 - 1.349 1.400 0.180
ENSG00000161904 E014 24.0748232 0.0027414519 2.030065e-01 4.856517e-01 6 33777138 33777153 16 - 1.343 1.425 0.285
ENSG00000161904 E015 40.0616741 0.0003808032 4.125832e-01 6.937571e-01 6 33777154 33777239 86 - 1.583 1.623 0.137
ENSG00000161904 E016 37.4461499 0.0003770657 2.288248e-01 5.175257e-01 6 33778242 33778318 77 - 1.611 1.554 -0.194
ENSG00000161904 E017 19.0430477 0.0006967335 7.572323e-03 6.657780e-02 6 33778319 33778330 12 - 1.390 1.214 -0.615
ENSG00000161904 E018 24.6283767 0.0012039910 8.692076e-02 3.055412e-01 6 33778331 33778387 57 - 1.459 1.358 -0.350
ENSG00000161904 E019 4.2815734 0.0034154171 7.529867e-05 1.871502e-03 6 33778388 33780001 1614 - 0.327 0.870 2.514
ENSG00000161904 E020 0.3712740 0.0165782656 7.683491e-01   6 33780002 33780099 98 - 0.107 0.154 0.607
ENSG00000161904 E021 32.9440116 0.0011589927 3.167629e-02 1.681279e-01 6 33780100 33780179 80 - 1.586 1.475 -0.382
ENSG00000161904 E022 0.0000000       6 33780180 33780299 120 -      
ENSG00000161904 E023 32.9962685 0.0004613708 1.436144e-01 4.035479e-01 6 33781077 33781153 77 - 1.567 1.493 -0.253
ENSG00000161904 E024 1.9955080 0.0077247327 1.362228e-01 3.925330e-01 6 33781154 33781356 203 - 0.327 0.552 1.192
ENSG00000161904 E025 6.7805588 0.0020303100 8.770768e-06 3.047955e-04 6 33781357 33782246 890 - 0.511 1.034 2.131
ENSG00000161904 E026 27.0320055 0.0009130379 5.848865e-01 8.155235e-01 6 33784352 33784427 76 - 1.459 1.429 -0.103
ENSG00000161904 E027 97.7103807 0.0001786875 1.954939e-30 1.172476e-27 6 33784428 33786733 2306 - 1.732 2.107 1.259
ENSG00000161904 E028 20.1731549 0.0007802717 2.143157e-02 1.325512e-01 6 33786734 33786774 41 - 1.400 1.252 -0.515
ENSG00000161904 E029 8.6224013 0.0036712983 2.621132e-04 5.214323e-03 6 33786775 33786873 99 - 0.717 1.098 1.455
ENSG00000161904 E030 79.4379164 0.0009455669 1.501622e-12 1.905611e-10 6 33786874 33788380 1507 - 1.728 1.989 0.880
ENSG00000161904 E031 42.1736145 0.0003706425 6.280470e-11 6.489097e-09 6 33788381 33788774 394 - 1.777 1.481 -1.009
ENSG00000161904 E032 38.4097501 0.0003772786 5.485375e-10 4.922599e-08 6 33788775 33789203 429 - 1.737 1.443 -1.004

Help

Please Click HERE to learn more details about the results from DEXseq.