ENSG00000162104

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000294016 ENSG00000162104 No_inf pgKDN_inf ADCY9 protein_coding protein_coding 13.44602 26.77589 7.86042 0.7971387 0.5031383 -1.766961 2.2802688 2.761711 2.3838531 0.5894010 0.4684294 -0.211442 0.24349167 0.105275 0.314700 0.209425 0.265522800 0.006154525 FALSE TRUE
ENST00000571467 ENSG00000162104 No_inf pgKDN_inf ADCY9 protein_coding nonsense_mediated_decay 13.44602 26.77589 7.86042 0.7971387 0.5031383 -1.766961 1.1054555 3.316366 0.0000000 0.7544334 0.0000000 -8.377803 0.04094167 0.122825 0.000000 -0.122825 0.006154525 0.006154525 TRUE TRUE
MSTRG.10534.13 ENSG00000162104 No_inf pgKDN_inf ADCY9 protein_coding   13.44602 26.77589 7.86042 0.7971387 0.5031383 -1.766961 0.1726321 0.000000 0.5178963 0.0000000 0.5178963 5.722183 0.01924167 0.000000 0.057725 0.057725 0.657963793 0.006154525 FALSE TRUE
MSTRG.10534.3 ENSG00000162104 No_inf pgKDN_inf ADCY9 protein_coding   13.44602 26.77589 7.86042 0.7971387 0.5031383 -1.766961 3.8209147 8.333897 1.8296647 1.7907267 0.7518824 -2.181278 0.25664167 0.306425 0.238525 -0.067900 0.836911496 0.006154525 FALSE TRUE
MSTRG.10534.5 ENSG00000162104 No_inf pgKDN_inf ADCY9 protein_coding   13.44602 26.77589 7.86042 0.7971387 0.5031383 -1.766961 3.3815038 6.617109 2.3624133 2.4286666 0.7775670 -1.482024 0.24357500 0.243300 0.294650 0.051350 0.895456533 0.006154525 FALSE TRUE
MSTRG.10534.6 ENSG00000162104 No_inf pgKDN_inf ADCY9 protein_coding   13.44602 26.77589 7.86042 0.7971387 0.5031383 -1.766961 1.4961940 3.618623 0.0000000 2.8991825 0.0000000 -8.503278 0.10215000 0.143000 0.000000 -0.143000 0.793818864 0.006154525 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000162104 E001 0.2542726 0.2376225556 1.000000e+00   16 3953387 3953516 130 - 0.000 0.102 8.572
ENSG00000162104 E002 0.7529080 0.7518605045 8.315274e-01 0.9392186749 16 3962653 3962657 5 - 0.163 0.220 0.539
ENSG00000162104 E003 1.1245601 0.4728795257 9.625484e-01 0.9918625574 16 3962658 3962674 17 - 0.281 0.284 0.024
ENSG00000162104 E004 370.3604752 0.0001183152 6.559407e-02 0.2580262935 16 3962675 3966966 4292 - 2.467 2.488 0.070
ENSG00000162104 E005 5.2427732 0.0049325538 8.438920e-01 0.9441853758 16 3974669 3974710 42 - 0.743 0.718 -0.103
ENSG00000162104 E006 11.0829589 0.0206892559 3.733833e-01 0.6610984345 16 3977482 3977630 149 - 1.075 0.982 -0.343
ENSG00000162104 E007 11.5222115 0.0025277622 4.931234e-01 0.7550996344 16 3979116 3979275 160 - 0.962 1.032 0.258
ENSG00000162104 E008 7.9951504 0.0021959293 9.024385e-01 0.9688307125 16 3981773 3983231 1459 - 0.866 0.881 0.055
ENSG00000162104 E009 9.8354746 0.0015200668 3.983541e-01 0.6823221151 16 3983232 3983391 160 - 1.022 0.937 -0.315
ENSG00000162104 E010 6.3650868 0.0487018261 8.491436e-01 0.9464293487 16 3983392 3983440 49 - 0.809 0.789 -0.081
ENSG00000162104 E011 0.8816471 0.0238931609 6.196206e-01 0.8354688036 16 3983441 3984150 710 - 0.162 0.253 0.804
ENSG00000162104 E012 8.7550886 0.0029925619 8.252758e-01 0.9367065632 16 3988994 3989083 90 - 0.892 0.917 0.093
ENSG00000162104 E013 4.2766889 0.0481339092 3.146744e-01 0.6076277825 16 3989084 3989088 5 - 0.514 0.684 0.755
ENSG00000162104 E014 4.5304583 0.0370589347 2.360059e-01 0.5252886246 16 3989089 3989096 8 - 0.514 0.707 0.851
ENSG00000162104 E015 6.0062704 0.0114485912 7.793129e-01 0.9149983786 16 3992146 3992221 76 - 0.743 0.779 0.145
ENSG00000162104 E016 3.3726311 0.0058076070 9.680497e-01 0.9936017440 16 3992222 3992270 49 - 0.571 0.577 0.026
ENSG00000162104 E017 2.7665074 0.0053176247 2.935720e-01 0.5871797764 16 3992271 3992285 15 - 0.373 0.545 0.882
ENSG00000162104 E018 5.5140393 0.0025897565 4.816465e-01 0.7466622020 16 3992286 3992363 78 - 0.666 0.760 0.389
ENSG00000162104 E019 0.9865319 0.0120618330 3.442197e-01 0.6355543668 16 3992364 3992367 4 - 0.373 0.220 -1.044
ENSG00000162104 E020 4.6799156 0.0031145065 4.206118e-03 0.0440130599 16 3993349 3993405 57 - 0.280 0.750 2.348
ENSG00000162104 E021 9.1949289 0.0014915216 1.051628e-02 0.0830188776 16 3993406 3993510 105 - 0.666 0.981 1.241
ENSG00000162104 E022 11.9297134 0.0013799258 1.021311e-01 0.3339600267 16 3993511 3993975 465 - 0.892 1.063 0.634
ENSG00000162104 E023 0.4911106 0.0161098062 2.273113e-01   16 4003492 4003507 16 - 0.280 0.102 -1.781
ENSG00000162104 E024 8.2093940 0.0019459127 2.377613e-01 0.5267371828 16 4007368 4007558 191 - 0.983 0.858 -0.474
ENSG00000162104 E025 0.0000000       16 4015562 4015682 121 -      
ENSG00000162104 E026 0.0000000       16 4054035 4054190 156 -      
ENSG00000162104 E027 48.6330591 0.0003263778 5.338144e-06 0.0001991061 16 4113750 4115485 1736 - 1.765 1.558 -0.703
ENSG00000162104 E028 6.0408919 0.0088400701 5.866458e-03 0.0555480277 16 4115690 4116442 753 - 1.003 0.684 -1.245

Help

Please Click HERE to learn more details about the results from DEXseq.