ENSG00000162231

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000294172 ENSG00000162231 No_inf pgKDN_inf NXF1 protein_coding protein_coding 83.65162 108.3193 68.87672 8.012835 4.32271 -0.6531252 17.432628 12.966832 19.034342 1.4898313 1.6189744 0.5534242 0.22780000 0.124025 0.283200 0.159175 0.05676200 0.03738301 FALSE  
ENST00000527902 ENSG00000162231 No_inf pgKDN_inf NXF1 protein_coding protein_coding 83.65162 108.3193 68.87672 8.012835 4.32271 -0.6531252 20.636369 24.487888 19.229914 4.6161027 3.2351714 -0.3485550 0.24576667 0.220400 0.274175 0.053775 0.80158258 0.03738301 FALSE  
ENST00000531709 ENSG00000162231 No_inf pgKDN_inf NXF1 protein_coding protein_coding 83.65162 108.3193 68.87672 8.012835 4.32271 -0.6531252 23.453901 33.535671 16.034450 0.9934996 0.6121626 -1.0640522 0.27697500 0.313675 0.234325 -0.079350 0.41143637 0.03738301 TRUE  
ENST00000533048 ENSG00000162231 No_inf pgKDN_inf NXF1 protein_coding protein_coding_CDS_not_defined 83.65162 108.3193 68.87672 8.012835 4.32271 -0.6531252 6.481089 12.403712 2.151696 1.0638480 2.1516960 -2.5216990 0.07111667 0.115425 0.028875 -0.086550 0.03738301 0.03738301    
ENST00000533440 ENSG00000162231 No_inf pgKDN_inf NXF1 protein_coding retained_intron 83.65162 108.3193 68.87672 8.012835 4.32271 -0.6531252 5.683887 8.587336 5.563257 0.3183123 1.5161874 -0.6253692 0.06695833 0.081350 0.083150 0.001800 0.97601577 0.03738301 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000162231 E001 0.2451451 0.0165830171 6.716890e-01   11 62792123 62792129 7 - 0.121 0.074 -0.787
ENSG00000162231 E002 2.8693778 0.0475380706 3.268924e-01 0.6193230526 11 62792130 62792170 41 - 0.467 0.620 0.715
ENSG00000162231 E003 15.9858734 0.0057325409 5.632665e-01 0.8026964426 11 62792171 62792230 60 - 1.180 1.226 0.162
ENSG00000162231 E004 48.7614105 0.0039166006 8.727864e-01 0.9565453961 11 62792231 62792352 122 - 1.672 1.679 0.024
ENSG00000162231 E005 48.7873556 0.0003004854 4.064056e-01 0.6891032767 11 62792353 62792414 62 - 1.701 1.664 -0.126
ENSG00000162231 E006 30.8387073 0.0004533118 2.858623e-01 0.5794165672 11 62792415 62792417 3 - 1.521 1.462 -0.202
ENSG00000162231 E007 64.1067314 0.0003285673 3.717564e-02 0.1856296756 11 62792418 62792514 97 - 1.844 1.764 -0.271
ENSG00000162231 E008 0.9982446 0.1225489518 5.188009e-01 0.7736612477 11 62792515 62792640 126 - 0.216 0.326 0.797
ENSG00000162231 E009 47.7487572 0.0009071159 9.369751e-03 0.0770554722 11 62792641 62792701 61 - 1.741 1.623 -0.398
ENSG00000162231 E010 64.6910712 0.0022049400 4.243704e-01 0.7035532806 11 62794258 62794337 80 - 1.819 1.785 -0.115
ENSG00000162231 E011 58.5464207 0.0002702994 5.232249e-01 0.7766547987 11 62794338 62794398 61 - 1.738 1.764 0.086
ENSG00000162231 E012 47.8222770 0.0005213676 6.078773e-01 0.8291753062 11 62794399 62794440 42 - 1.684 1.660 -0.080
ENSG00000162231 E013 2.8485135 0.0050279097 8.489329e-01 0.9464293487 11 62794441 62794628 188 - 0.553 0.579 0.120
ENSG00000162231 E014 2.2158211 0.0063097577 5.069970e-01 0.7656151810 11 62794751 62794934 184 - 0.553 0.457 -0.465
ENSG00000162231 E015 60.6448734 0.0002861473 5.783553e-01 0.8115783174 11 62794935 62795007 73 - 1.755 1.777 0.074
ENSG00000162231 E016 1.8783185 0.0073298783 1.637854e-01 0.4327577755 11 62795008 62795400 393 - 0.293 0.510 1.213
ENSG00000162231 E017 46.8129410 0.0047466038 4.228237e-01 0.7020896900 11 62795901 62795943 43 - 1.631 1.674 0.145
ENSG00000162231 E018 62.7785373 0.0003080958 3.017132e-01 0.5949699028 11 62796066 62796148 83 - 1.758 1.798 0.137
ENSG00000162231 E019 37.2064434 0.0003777246 1.431922e-01 0.4029705615 11 62796149 62796181 33 - 1.512 1.587 0.256
ENSG00000162231 E020 36.1026069 0.0005200236 9.807460e-01 0.9979728757 11 62796287 62796304 18 - 1.549 1.550 0.003
ENSG00000162231 E021 42.6577128 0.0022354812 9.469426e-01 0.9858970846 11 62796305 62796342 38 - 1.618 1.621 0.010
ENSG00000162231 E022 29.5264841 0.0103276953 8.079295e-01 0.9291044418 11 62796343 62796345 3 - 1.476 1.459 -0.060
ENSG00000162231 E023 67.6223047 0.0002823919 1.623370e-01 0.4307529558 11 62796460 62796567 108 - 1.850 1.797 -0.178
ENSG00000162231 E024 1.6066077 0.0168499002 9.003996e-01 0.9676819688 11 62796942 62797182 241 - 0.416 0.396 -0.109
ENSG00000162231 E025 51.1287708 0.0002747861 4.149519e-01 0.6951395581 11 62797183 62797238 56 - 1.720 1.684 -0.121
ENSG00000162231 E026 49.1613156 0.0003310774 4.148861e-01 0.6950940906 11 62797318 62797386 69 - 1.703 1.667 -0.123
ENSG00000162231 E027 31.2665930 0.0075306129 7.392960e-02 0.2770125638 11 62798539 62798575 37 - 1.561 1.445 -0.399
ENSG00000162231 E028 36.7328647 0.0004108385 3.016379e-04 0.0058310175 11 62798576 62798844 269 - 1.422 1.615 0.664
ENSG00000162231 E029 76.4790271 0.0005711107 4.217634e-05 0.0011558632 11 62798845 62799256 412 - 1.763 1.917 0.520
ENSG00000162231 E030 127.5345634 0.0003491251 2.332962e-06 0.0000967892 11 62799257 62800112 856 - 1.996 2.131 0.454
ENSG00000162231 E031 54.1360996 0.0002664713 1.517880e-02 0.1060231847 11 62800113 62800376 264 - 1.651 1.755 0.354
ENSG00000162231 E032 50.9041771 0.0003345142 6.301709e-01 0.8413866518 11 62800377 62800486 110 - 1.709 1.687 -0.073
ENSG00000162231 E033 40.2680587 0.0023065263 6.504884e-01 0.8528853479 11 62801094 62801201 108 - 1.611 1.587 -0.083
ENSG00000162231 E034 41.0433926 0.0003664641 1.025171e-03 0.0152850158 11 62801329 62801417 89 - 1.698 1.543 -0.527
ENSG00000162231 E035 33.9778381 0.0004291632 6.164634e-01 0.8337095564 11 62801562 62801631 70 - 1.541 1.514 -0.092
ENSG00000162231 E036 39.8085776 0.0049919806 9.720789e-01 0.9947660217 11 62801739 62801819 81 - 1.590 1.591 0.003
ENSG00000162231 E037 29.2995897 0.0095020759 1.768314e-01 0.4511886713 11 62801942 62801973 32 - 1.520 1.427 -0.323
ENSG00000162231 E038 23.8187767 0.0044580988 5.656133e-01 0.8043894471 11 62801974 62802003 30 - 1.400 1.361 -0.134
ENSG00000162231 E039 27.6923356 0.0005189528 9.740594e-01 0.9953877330 11 62802004 62802046 43 - 1.437 1.439 0.005
ENSG00000162231 E040 36.0842962 0.0004083339 8.282448e-01 0.9377449464 11 62802177 62802260 84 - 1.557 1.545 -0.040
ENSG00000162231 E041 43.1188060 0.0009179336 7.630433e-02 0.2823213076 11 62803419 62803549 131 - 1.678 1.593 -0.288
ENSG00000162231 E042 16.6762227 0.0008325258 7.997222e-01 0.9248736584 11 62803550 62803572 23 - 1.241 1.221 -0.067
ENSG00000162231 E043 0.2454921 0.0168894560 6.723476e-01   11 62803573 62803791 219 - 0.121 0.074 -0.787
ENSG00000162231 E044 14.7172241 0.0073313914 9.076306e-01 0.9706757280 11 62803792 62803799 8 - 1.171 1.181 0.034
ENSG00000162231 E045 37.2394762 0.0003647145 1.876796e-01 0.4658330140 11 62803800 62803933 134 - 1.605 1.538 -0.226
ENSG00000162231 E046 16.2414680 0.0062030817 1.611967e-01 0.4293538014 11 62803934 62803978 45 - 1.286 1.175 -0.391
ENSG00000162231 E047 0.4810357 0.0351731301 1.286465e-01   11 62803979 62804081 103 - 0.293 0.074 -2.372
ENSG00000162231 E048 0.9882921 0.0162137908 9.631134e-01 0.9921323282 11 62804082 62804210 129 - 0.293 0.286 -0.050
ENSG00000162231 E049 0.9969164 0.0165916297 4.861779e-01 0.7499790443 11 62805103 62805328 226 - 0.216 0.326 0.798
ENSG00000162231 E050 21.6220453 0.0014384020 7.888156e-01 0.9189559069 11 62805329 62805874 546 - 1.347 1.329 -0.064
ENSG00000162231 E051 0.7514889 0.0146629773 2.914926e-01 0.5850026562 11 62806191 62806302 112 - 0.121 0.286 1.535

Help

Please Click HERE to learn more details about the results from DEXseq.