ENSG00000162604

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000472357 ENSG00000162604 No_inf pgKDN_inf TM2D1 protein_coding retained_intron 46.98321 49.55341 49.38224 1.975959 2.628751 -0.00499101 2.239048 3.602730 1.2387731 0.8971247 0.5182866 -1.5325781 0.04635833 0.073950 0.023750 -0.050200 0.446699596 0.002509415   FALSE
ENST00000472989 ENSG00000162604 No_inf pgKDN_inf TM2D1 protein_coding protein_coding_CDS_not_defined 46.98321 49.55341 49.38224 1.975959 2.628751 -0.00499101 13.729117 19.548160 12.8014777 0.8148207 5.2837820 -0.6103338 0.28389167 0.397500 0.244625 -0.152875 0.715059608 0.002509415 FALSE FALSE
ENST00000606498 ENSG00000162604 No_inf pgKDN_inf TM2D1 protein_coding protein_coding 46.98321 49.55341 49.38224 1.975959 2.628751 -0.00499101 14.416316 2.916876 20.6223082 2.9168756 1.9350895 2.8174719 0.31929167 0.052675 0.426875 0.374200 0.002509415 0.002509415 FALSE TRUE
MSTRG.1090.10 ENSG00000162604 No_inf pgKDN_inf TM2D1 protein_coding   46.98321 49.55341 49.38224 1.975959 2.628751 -0.00499101 7.001845 8.734719 6.0896263 3.3588082 3.6009379 -0.5196911 0.14481667 0.170475 0.130800 -0.039675 0.842085267 0.002509415 TRUE FALSE
MSTRG.1090.3 ENSG00000162604 No_inf pgKDN_inf TM2D1 protein_coding   46.98321 49.55341 49.38224 1.975959 2.628751 -0.00499101 2.753022 6.804104 0.7989631 3.9554700 0.7989631 -3.0743781 0.05798333 0.143875 0.015550 -0.128325 0.792589094 0.002509415 TRUE TRUE
MSTRG.1090.5 ENSG00000162604 No_inf pgKDN_inf TM2D1 protein_coding   46.98321 49.55341 49.38224 1.975959 2.628751 -0.00499101 3.769976 3.002722 5.1833840 1.0171515 3.0009845 0.7856076 0.08160000 0.060700 0.101350 0.040650 0.920517375 0.002509415 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000162604 E001 0.1265070 0.0122838668 5.307521e-01   1 61681046 61681046 1 - 0.000 0.096 10.136
ENSG00000162604 E002 0.2451451 0.0164520958 9.919741e-01   1 61681047 61681047 1 - 0.094 0.096 0.022
ENSG00000162604 E003 0.3627758 0.0166369025 5.923494e-01   1 61681048 61681048 1 - 0.172 0.096 -0.977
ENSG00000162604 E004 3.5373282 0.0852438807 7.537541e-01 0.903118471 1 61681049 61681122 74 - 0.689 0.624 -0.277
ENSG00000162604 E005 20.7071076 0.0124486989 8.964120e-01 0.965952538 1 61681123 61681244 122 - 1.330 1.342 0.039
ENSG00000162604 E006 28.9027610 0.0005476763 8.070233e-01 0.928812320 1 61681245 61681350 106 - 1.469 1.482 0.047
ENSG00000162604 E007 3.6183194 0.0041249796 4.157219e-03 0.043664162 1 61683272 61683416 145 - 0.431 0.808 1.675
ENSG00000162604 E008 22.9837460 0.0007010968 6.174569e-01 0.834340308 1 61683417 61683451 35 - 1.394 1.366 -0.100
ENSG00000162604 E009 28.3740221 0.0005062276 6.649379e-01 0.860699413 1 61683452 61683496 45 - 1.479 1.457 -0.077
ENSG00000162604 E010 29.7172545 0.0004928790 7.263061e-01 0.890427886 1 61683497 61683546 50 - 1.496 1.479 -0.061
ENSG00000162604 E011 3.1178940 0.0091818156 8.218365e-03 0.070379375 1 61683547 61683857 311 - 0.390 0.755 1.686
ENSG00000162604 E012 12.2538725 0.0019021290 2.823695e-03 0.032999603 1 61686792 61686895 104 - 0.978 1.225 0.893
ENSG00000162604 E013 4.8157646 0.0033101437 1.396943e-01 0.397523983 1 61686896 61686921 26 - 0.667 0.840 0.701
ENSG00000162604 E014 0.2539903 0.0161825106 2.374195e-01   1 61694154 61694696 543 - 0.000 0.174 11.139
ENSG00000162604 E015 15.4961110 0.0044084321 4.970850e-01 0.757887359 1 61694697 61694697 1 - 1.243 1.192 -0.182
ENSG00000162604 E016 32.8793118 0.0005968997 6.564608e-01 0.856188388 1 61694698 61694770 73 - 1.541 1.519 -0.074
ENSG00000162604 E017 0.8528206 0.0209886735 7.238175e-01 0.889056810 1 61696065 61696241 177 - 0.295 0.241 -0.392
ENSG00000162604 E018 9.4704294 0.0110944144 7.367823e-05 0.001835456 1 61697509 61700274 2766 - 0.768 1.171 1.508
ENSG00000162604 E019 35.4225968 0.0004083429 3.285942e-01 0.621108282 1 61700934 61701025 92 - 1.584 1.538 -0.157
ENSG00000162604 E020 33.1871463 0.0033637846 9.646959e-01 0.992558043 1 61709329 61709437 109 - 1.532 1.535 0.012
ENSG00000162604 E021 19.6046002 0.0007902485 8.041615e-01 0.927279590 1 61723713 61723772 60 - 1.305 1.322 0.059
ENSG00000162604 E022 11.4463764 0.0012028324 1.660945e-01 0.436216445 1 61723773 61723784 12 - 1.150 1.036 -0.410
ENSG00000162604 E023 9.2674998 0.0017364116 3.915244e-01 0.676636639 1 61723785 61723786 2 - 1.049 0.973 -0.282
ENSG00000162604 E024 0.9576759 0.1820299759 2.635964e-01 0.556660922 1 61724288 61724425 138 - 0.390 0.174 -1.560
ENSG00000162604 E025 0.7365069 0.0156586289 9.855979e-01 0.999045940 1 61724902 61724919 18 - 0.238 0.241 0.023
ENSG00000162604 E026 0.8532285 0.0122674032 7.215776e-01 0.887959507 1 61724920 61724954 35 - 0.295 0.241 -0.392
ENSG00000162604 E027 0.2459655 0.0166798890 9.919489e-01   1 61724955 61724956 2 - 0.094 0.096 0.023
ENSG00000162604 E028 23.3501455 0.0076585919 1.625464e-02 0.110768833 1 61724957 61725423 467 - 1.461 1.301 -0.556

Help

Please Click HERE to learn more details about the results from DEXseq.