ENSG00000162688

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361915 ENSG00000162688 No_inf pgKDN_inf AGL protein_coding protein_coding 4.191503 3.301154 4.950917 0.267138 0.2200763 0.5832728 0.8166641 1.2202394 0.5556243 0.7077002 0.5556243 -1.1210230 0.22453333 0.40915 0.100850 -0.308300 0.78549847 0.04490623 FALSE TRUE
ENST00000370161 ENSG00000162688 No_inf pgKDN_inf AGL protein_coding protein_coding 4.191503 3.301154 4.950917 0.267138 0.2200763 0.5832728 1.6758975 0.4433997 3.3903932 0.4433997 0.3088637 2.9068463 0.36507500 0.13385 0.693375 0.559525 0.04490623 0.04490623 FALSE TRUE
ENST00000370163 ENSG00000162688 No_inf pgKDN_inf AGL protein_coding protein_coding 4.191503 3.301154 4.950917 0.267138 0.2200763 0.5832728 0.3460047 1.0380141 0.0000000 0.6710792 0.0000000 -6.7115143 0.09443333 0.28330 0.000000 -0.283300 0.44337010 0.04490623 FALSE TRUE
ENST00000370165 ENSG00000162688 No_inf pgKDN_inf AGL protein_coding protein_coding 4.191503 3.301154 4.950917 0.267138 0.2200763 0.5832728 0.3789329 0.0000000 0.0000000 0.0000000 0.0000000 0.0000000 0.08812500 0.00000 0.000000 0.000000   0.04490623 FALSE TRUE
MSTRG.1405.1 ENSG00000162688 No_inf pgKDN_inf AGL protein_coding   4.191503 3.301154 4.950917 0.267138 0.2200763 0.5832728 0.9312731 0.5995003 0.8767056 0.2051017 0.3906633 0.5408283 0.22007500 0.17370 0.182500 0.008800 0.99770072 0.04490623 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000162688 E001 1.6985168 0.120487411 0.621488990 0.83668781 1 99850159 99850360 202 + 0.469 0.377 -0.492
ENSG00000162688 E002 0.8525342 0.012955559 0.956852499 0.98975055 1 99850361 99850415 55 + 0.271 0.263 -0.059
ENSG00000162688 E003 0.0000000       1 99850489 99850618 130 +      
ENSG00000162688 E004 0.0000000       1 99850619 99850898 280 +      
ENSG00000162688 E005 1.3349596 0.010049725 0.618108920 0.83476278 1 99850975 99851034 60 + 0.400 0.324 -0.452
ENSG00000162688 E006 1.7255616 0.008365059 0.323281560 0.61595604 1 99851035 99851124 90 + 0.361 0.507 0.771
ENSG00000162688 E007 0.0000000       1 99852561 99852669 109 +      
ENSG00000162688 E008 0.0000000       1 99852670 99852703 34 +      
ENSG00000162688 E009 0.0000000       1 99861210 99861502 293 +      
ENSG00000162688 E010 2.0879565 0.007023125 0.456062207 0.72850115 1 99861503 99861713 211 + 0.436 0.543 0.526
ENSG00000162688 E011 1.5807611 0.018525843 0.704520168 0.87987977 1 99862257 99862423 167 + 0.436 0.377 -0.322
ENSG00000162688 E012 2.5489490 0.005739547 0.596889712 0.82294470 1 99864386 99864589 204 + 0.581 0.507 -0.345
ENSG00000162688 E013 2.6420669 0.005497981 0.040133544 0.19418342 1 99870400 99870581 182 + 0.670 0.377 -1.410
ENSG00000162688 E014 0.7250197 0.014263052 0.601535127 0.82575208 1 99870758 99870869 112 + 0.271 0.191 -0.644
ENSG00000162688 E015 0.1187032 0.011873613 0.692399723   1 99874470 99874686 217 + 0.085 0.000 -8.970
ENSG00000162688 E016 0.4814165 0.033574785 0.459200475   1 99874687 99874810 124 + 0.217 0.106 -1.229
ENSG00000162688 E017 1.3496573 0.009919913 0.479746376 0.74532355 1 99875154 99875256 103 + 0.318 0.425 0.619
ENSG00000162688 E018 1.3511731 0.009804271 0.480976208 0.74618791 1 99875358 99875455 98 + 0.318 0.425 0.619
ENSG00000162688 E019 1.7040352 0.009194385 0.940442067 0.98305687 1 99876458 99876597 140 + 0.436 0.425 -0.059
ENSG00000162688 E020 3.2947772 0.008390421 0.949317812 0.98676383 1 99877641 99877828 188 + 0.628 0.636 0.034
ENSG00000162688 E021 1.6903421 0.017491723 0.251736481 0.54291248 1 99879923 99880046 124 + 0.500 0.324 -0.966
ENSG00000162688 E022 3.6612977 0.004476522 0.957734413 0.98990594 1 99880632 99880795 164 + 0.670 0.663 -0.031
ENSG00000162688 E023 2.4575016 0.006945065 0.322582836 0.61558951 1 99881076 99881177 102 + 0.469 0.607 0.645
ENSG00000162688 E024 2.5701288 0.005657297 0.729159983 0.89200270 1 99881292 99881447 156 + 0.529 0.576 0.218
ENSG00000162688 E025 3.9026232 0.105853797 0.912121800 0.97202289 1 99881541 99881691 151 + 0.690 0.688 -0.007
ENSG00000162688 E026 2.6810766 0.144899695 0.818167726 0.93382694 1 99884120 99884244 125 + 0.556 0.576 0.094
ENSG00000162688 E027 1.9505988 0.053875236 0.989241659 1.00000000 1 99884339 99884451 113 + 0.469 0.468 -0.007
ENSG00000162688 E028 2.8027819 0.004974474 0.971192085 0.99442370 1 99884569 99884703 135 + 0.581 0.576 -0.023
ENSG00000162688 E029 2.8046681 0.006655044 0.967042436 0.99337266 1 99887978 99888108 131 + 0.581 0.576 -0.023
ENSG00000162688 E030 3.6395838 0.003982857 0.427787394 0.70633296 1 99891220 99891356 137 + 0.709 0.607 -0.433
ENSG00000162688 E031 3.8713008 0.103505030 0.426491068 0.70504341 1 99891606 99891739 134 + 0.744 0.607 -0.576
ENSG00000162688 E032 3.3478974 0.019706040 0.005657101 0.05412632 1 99892432 99892607 176 + 0.776 0.377 -1.846
ENSG00000162688 E033 3.8538959 0.021844756 0.089272361 0.31017300 1 99896286 99896388 103 + 0.776 0.543 -0.998
ENSG00000162688 E034 6.6601146 0.002529183 0.158279062 0.42519112 1 99900636 99900861 226 + 0.944 0.797 -0.566
ENSG00000162688 E035 4.8914280 0.024850178 0.669149160 0.86233223 1 99902683 99902794 112 + 0.744 0.797 0.211
ENSG00000162688 E036 6.8182469 0.002276329 0.673555264 0.86483822 1 99910712 99910847 136 + 0.911 0.867 -0.165
ENSG00000162688 E037 4.7535718 0.003099721 0.972290181 0.99476602 1 99912405 99912517 113 + 0.760 0.756 -0.016
ENSG00000162688 E038 7.0726416 0.002174731 0.882364596 0.96044820 1 99913527 99913738 212 + 0.899 0.914 0.056
ENSG00000162688 E039 3.9191057 0.003724152 0.486215855 0.74998855 1 99915389 99915486 98 + 0.650 0.735 0.356
ENSG00000162688 E040 4.0119976 0.004182081 0.607065247 0.82902637 1 99916410 99916497 88 + 0.727 0.663 -0.266
ENSG00000162688 E041 5.9794316 0.028419358 0.947728885 0.98634234 1 99916598 99916731 134 + 0.835 0.851 0.061
ENSG00000162688 E042 77.5117308 0.001413279 0.013870194 0.09938555 1 99921534 99924023 2490 + 1.861 1.929 0.228

Help

Please Click HERE to learn more details about the results from DEXseq.