ENSG00000162736

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000294785 ENSG00000162736 No_inf pgKDN_inf NCSTN protein_coding protein_coding 171.3321 167.5128 168.2509 2.462637 2.173395 0.006342491 72.19060 57.64832 81.46700 2.974326 2.729736 0.4988641 0.4214333 0.34485 0.484850 0.140000 0.02749494 3.377984e-05 FALSE TRUE
ENST00000699554 ENSG00000162736 No_inf pgKDN_inf NCSTN protein_coding nonsense_mediated_decay 171.3321 167.5128 168.2509 2.462637 2.173395 0.006342491 78.18921 92.31233 69.24514 4.708731 3.142606 -0.4147585 0.4570750 0.55035 0.411325 -0.139025 0.01581951 3.377984e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000162736 E001 0.0000000       1 160343294 160343315 22 +      
ENSG00000162736 E002 0.0000000       1 160343316 160343324 9 +      
ENSG00000162736 E003 0.0000000       1 160343325 160343352 28 +      
ENSG00000162736 E004 0.0000000       1 160343353 160343382 30 +      
ENSG00000162736 E005 0.0000000       1 160343383 160343383 1 +      
ENSG00000162736 E006 0.0000000       1 160343384 160343386 3 +      
ENSG00000162736 E007 0.0000000       1 160343387 160343390 4 +      
ENSG00000162736 E008 0.0000000       1 160343391 160343392 2 +      
ENSG00000162736 E009 0.0000000       1 160343393 160343481 89 +      
ENSG00000162736 E010 0.0000000       1 160343662 160343703 42 +      
ENSG00000162736 E011 0.3625611 1.652207e-02 5.341430e-01   1 160343704 160343802 99 + 0.179 0.092 -1.111
ENSG00000162736 E012 0.2533610 1.596155e-02 2.717187e-01   1 160343803 160343888 86 + 0.000 0.168 10.862
ENSG00000162736 E013 0.0000000       1 160344476 160344614 139 +      
ENSG00000162736 E014 38.1290278 7.102250e-04 1.338313e-03 1.874334e-02 1 160344722 160344826 105 + 1.668 1.513 -0.529
ENSG00000162736 E015 0.3729107 1.952521e-01 6.772156e-01   1 160344827 160345171 345 + 0.098 0.168 0.889
ENSG00000162736 E016 1.0049114 3.209606e-02 3.836187e-02 1.891406e-01 1 160346720 160348998 2279 + 0.098 0.423 2.696
ENSG00000162736 E017 73.2183760 3.022536e-03 5.487219e-03 5.295181e-02 1 160348999 160349122 124 + 1.926 1.813 -0.381
ENSG00000162736 E018 0.2458395 1.639212e-02 9.493009e-01   1 160349486 160349548 63 + 0.098 0.092 -0.111
ENSG00000162736 E019 63.3932833 2.472750e-04 1.935316e-04 4.074134e-03 1 160349549 160349670 122 + 1.877 1.738 -0.468
ENSG00000162736 E020 73.6626712 2.041698e-04 1.136690e-06 5.217553e-05 1 160350105 160350250 146 + 1.954 1.786 -0.568
ENSG00000162736 E021 0.6162018 2.058235e-02 7.240936e-01 8.891065e-01 1 160350251 160350401 151 + 0.179 0.232 0.474
ENSG00000162736 E022 1.8608490 7.983465e-03 2.589832e-01 5.515210e-01 1 160350510 160351199 690 + 0.356 0.526 0.889
ENSG00000162736 E023 0.1271363 1.232189e-02 5.836781e-01   1 160351200 160351221 22 + 0.000 0.092 9.932
ENSG00000162736 E024 52.9881199 2.635687e-04 2.003825e-01 4.823481e-01 1 160351222 160351287 66 + 1.757 1.707 -0.171
ENSG00000162736 E025 46.9174685 3.003938e-04 4.544390e-01 7.270970e-01 1 160351288 160351335 48 + 1.695 1.665 -0.103
ENSG00000162736 E026 45.3497766 2.709081e-03 8.940335e-02 3.105081e-01 1 160351336 160351372 37 + 1.706 1.626 -0.274
ENSG00000162736 E027 2.2138083 6.347138e-03 7.687727e-01 9.106140e-01 1 160351373 160351695 323 + 0.482 0.526 0.211
ENSG00000162736 E028 86.9930832 1.981901e-04 6.028609e-02 2.464168e-01 1 160351696 160351805 110 + 1.974 1.915 -0.196
ENSG00000162736 E029 2.5099718 5.878309e-03 2.101211e-03 2.654643e-02 1 160351806 160352053 248 + 0.246 0.699 2.392
ENSG00000162736 E030 62.7147833 1.091610e-03 6.511980e-02 2.570284e-01 1 160352054 160352075 22 + 1.840 1.769 -0.240
ENSG00000162736 E031 78.3771214 1.874080e-04 1.531219e-03 2.080654e-02 1 160352076 160352125 50 + 1.952 1.847 -0.354
ENSG00000162736 E032 95.3197423 1.597616e-04 5.150378e-03 5.069912e-02 1 160352126 160352206 81 + 2.025 1.942 -0.281
ENSG00000162736 E033 128.4998554 1.388349e-04 5.801162e-02 2.411034e-01 1 160352887 160352991 105 + 2.136 2.088 -0.160
ENSG00000162736 E034 101.6517553 1.678024e-04 4.731603e-02 2.137268e-01 1 160353160 160353237 78 + 2.040 1.983 -0.191
ENSG00000162736 E035 2.0836772 1.188445e-02 9.430024e-01 9.841691e-01 1 160353238 160353322 85 + 0.482 0.494 0.059
ENSG00000162736 E036 3.2105063 4.394163e-03 3.369004e-01 6.288418e-01 1 160353323 160353501 179 + 0.549 0.678 0.567
ENSG00000162736 E037 3.2388997 5.552034e-03 3.097311e-02 1.657246e-01 1 160353502 160354117 616 + 0.444 0.738 1.330
ENSG00000162736 E038 51.6854820 2.820286e-04 5.186711e-01 7.736023e-01 1 160354118 160354136 19 + 1.734 1.709 -0.083
ENSG00000162736 E039 96.3489038 1.683801e-04 1.798427e-02 1.182563e-01 1 160354137 160354222 86 + 2.023 1.953 -0.235
ENSG00000162736 E040 90.9979761 2.434917e-04 3.933340e-02 1.920869e-01 1 160354223 160354290 68 + 1.995 1.932 -0.212
ENSG00000162736 E041 1.5048671 8.731331e-03 2.437349e-02 1.431778e-01 1 160354291 160354506 216 + 0.179 0.526 2.211
ENSG00000162736 E042 6.9707500 2.146829e-03 1.378392e-03 1.918957e-02 1 160354507 160355654 1148 + 0.683 1.028 1.340
ENSG00000162736 E043 115.1009472 1.582670e-04 5.225245e-01 7.759530e-01 1 160355655 160355757 103 + 2.072 2.056 -0.052
ENSG00000162736 E044 2.3231296 6.920661e-03 6.880772e-01 8.715079e-01 1 160355758 160355862 105 + 0.549 0.494 -0.263
ENSG00000162736 E045 126.9856564 1.688674e-04 5.888445e-02 2.433500e-01 1 160355863 160355958 96 + 2.077 2.130 0.178
ENSG00000162736 E046 5.7084487 3.078375e-03 3.792913e-02 1.879301e-01 1 160355959 160356259 301 + 0.683 0.919 0.936
ENSG00000162736 E047 124.6569044 4.552436e-04 3.191182e-02 1.688377e-01 1 160356260 160356347 88 + 2.063 2.126 0.209
ENSG00000162736 E048 7.7426397 3.254545e-02 1.439560e-03 1.979892e-02 1 160356348 160356599 252 + 0.683 1.082 1.536
ENSG00000162736 E049 193.0267226 5.956592e-04 4.979689e-01 7.584923e-01 1 160356600 160356754 155 + 2.277 2.295 0.060
ENSG00000162736 E050 18.0239562 2.928855e-02 2.335663e-03 2.866353e-02 1 160356755 160357040 286 + 1.086 1.394 1.087
ENSG00000162736 E051 164.6305163 1.217808e-04 3.218036e-01 6.148411e-01 1 160357041 160357128 88 + 2.204 2.230 0.085
ENSG00000162736 E052 222.3622676 9.281966e-05 3.984547e-02 1.935013e-01 1 160357129 160357253 125 + 2.324 2.367 0.145
ENSG00000162736 E053 8.7270004 2.177197e-03 1.741056e-04 3.735168e-03 1 160357254 160358148 895 + 0.747 1.122 1.420
ENSG00000162736 E054 865.4905457 1.570435e-04 1.711096e-09 1.394052e-07 1 160358149 160358952 804 + 2.903 2.963 0.201

Help

Please Click HERE to learn more details about the results from DEXseq.