ENSG00000162769

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000366971 ENSG00000162769 No_inf pgKDN_inf FLVCR1 protein_coding protein_coding 7.284558 4.182266 9.185574 1.105786 0.8535374 1.13321 3.5392482 1.3129200 5.0205101 0.1707524 0.5499756 1.926979 0.4928250 0.379800 0.584925 0.205125 0.80603558 0.01074198 FALSE TRUE
ENST00000419102 ENSG00000162769 No_inf pgKDN_inf FLVCR1 protein_coding protein_coding 7.284558 4.182266 9.185574 1.105786 0.8535374 1.13321 0.7878709 0.2048176 1.4542025 0.2048176 0.8439869 2.768931 0.1075083 0.057675 0.143925 0.086250 0.84324031 0.01074198 FALSE TRUE
ENST00000483790 ENSG00000162769 No_inf pgKDN_inf FLVCR1 protein_coding protein_coding_CDS_not_defined 7.284558 4.182266 9.185574 1.105786 0.8535374 1.13321 1.1002408 1.6841021 0.3105918 0.2592261 0.3105918 -2.401712 0.2019667 0.431075 0.031350 -0.399725 0.01074198 0.01074198 FALSE TRUE
MSTRG.2671.4 ENSG00000162769 No_inf pgKDN_inf FLVCR1 protein_coding   7.284558 4.182266 9.185574 1.105786 0.8535374 1.13321 1.4636072 0.3517574 2.4002700 0.3517574 0.8466306 2.736100 0.1484417 0.047150 0.239800 0.192650 0.50721059 0.01074198 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000162769 E001 5.6542378 0.0026839311 0.420034759 0.69944398 1 212858275 212858915 641 + 0.826 0.734 -0.367
ENSG00000162769 E002 4.5015801 0.1405900611 0.370217778 0.65849670 1 212858916 212859190 275 + 0.661 0.814 0.623
ENSG00000162769 E003 0.2346346 0.0158160762 0.683868905   1 212863631 212863724 94 + 0.122 0.000 -12.121
ENSG00000162769 E004 4.3334866 0.0043726699 0.439617277 0.71555033 1 212863725 212863869 145 + 0.732 0.635 -0.408
ENSG00000162769 E005 0.1272623 0.0123795351 0.221561965   1 212864393 212864411 19 + 0.000 0.136 11.800
ENSG00000162769 E006 0.2373413 0.0158114236 0.683999049   1 212864412 212864519 108 + 0.122 0.000 -12.121
ENSG00000162769 E007 0.1272623 0.0123795351 0.221561965   1 212870054 212870166 113 + 0.000 0.136 11.800
ENSG00000162769 E008 6.4536394 0.0031906407 0.016534250 0.11198492 1 212872678 212872818 141 + 0.920 0.635 -1.145
ENSG00000162769 E009 3.2295059 0.0042939040 0.146367537 0.40737882 1 212883371 212883408 38 + 0.661 0.453 -0.960
ENSG00000162769 E010 1.9340144 0.0364072858 0.970591842 0.99413999 1 212883409 212883438 30 + 0.446 0.453 0.039
ENSG00000162769 E011 5.0620963 0.0049555490 0.746609369 0.89974560 1 212885293 212885396 104 + 0.770 0.734 -0.145
ENSG00000162769 E012 0.2545247 0.1795019645 0.086899622   1 212885397 212885565 169 + 0.000 0.240 12.327
ENSG00000162769 E013 2.3851256 0.0067073023 0.103141582 0.33563642 1 212887891 212887894 4 + 0.576 0.323 -1.325
ENSG00000162769 E014 6.6055749 0.0038563422 0.234607759 0.52367139 1 212887895 212888001 107 + 0.894 0.762 -0.515
ENSG00000162769 E015 7.6629576 0.0020941702 0.055377509 0.23445924 1 212888489 212888594 106 + 0.969 0.762 -0.795
ENSG00000162769 E016 6.8595452 0.0021824891 0.449185557 0.72301317 1 212889146 212889257 112 + 0.894 0.814 -0.308
ENSG00000162769 E017 3.1556192 0.0047553938 0.409713088 0.69188633 1 212894986 212895053 68 + 0.557 0.670 0.499
ENSG00000162769 E018 101.2994595 0.0002016757 0.001430161 0.01970729 1 212895216 212899363 4148 + 1.959 2.023 0.216

Help

Please Click HERE to learn more details about the results from DEXseq.