ENSG00000162819

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000340934 ENSG00000162819 No_inf pgKDN_inf BROX protein_coding protein_coding 46.01056 50.36574 49.07426 1.929346 2.093205 -0.03746851 14.931644 9.6736076 17.157861 2.7134414 3.7067885 0.8260938 0.34116667 0.195800 0.357425 0.161625 5.339835e-01 8.96268e-14 FALSE TRUE
ENST00000496267 ENSG00000162819 No_inf pgKDN_inf BROX protein_coding protein_coding_CDS_not_defined 46.01056 50.36574 49.07426 1.929346 2.093205 -0.03746851 3.623962 5.4532641 2.814021 1.1296066 0.7888832 -0.9520123 0.07610000 0.106125 0.055725 -0.050400 6.823144e-01 8.96268e-14   FALSE
MSTRG.2734.10 ENSG00000162819 No_inf pgKDN_inf BROX protein_coding   46.01056 50.36574 49.07426 1.929346 2.093205 -0.03746851 8.412114 15.7816110 0.000000 3.0639702 0.0000000 -10.6249426 0.18611667 0.319525 0.000000 -0.319525 8.962680e-14 8.96268e-14 FALSE TRUE
MSTRG.2734.19 ENSG00000162819 No_inf pgKDN_inf BROX protein_coding   46.01056 50.36574 49.07426 1.929346 2.093205 -0.03746851 2.542284 6.4747829 0.000000 3.8001825 0.0000000 -9.3409145 0.04970833 0.121625 0.000000 -0.121625 4.840027e-01 8.96268e-14 FALSE TRUE
MSTRG.2734.5 ENSG00000162819 No_inf pgKDN_inf BROX protein_coding   46.01056 50.36574 49.07426 1.929346 2.093205 -0.03746851 3.123411 0.4362171 7.491051 0.4362171 2.1296066 4.0712749 0.06659167 0.009675 0.149900 0.140225 1.929223e-02 8.96268e-14 FALSE TRUE
MSTRG.2734.7 ENSG00000162819 No_inf pgKDN_inf BROX protein_coding   46.01056 50.36574 49.07426 1.929346 2.093205 -0.03746851 7.547514 6.4257089 14.536808 0.8600268 1.6061035 1.1765317 0.15604167 0.126950 0.296300 0.169350 3.161919e-02 8.96268e-14 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000162819 E001 0.0000000       1 222712553 222712558 6 +      
ENSG00000162819 E002 0.0000000       1 222712559 222712563 5 +      
ENSG00000162819 E003 0.0000000       1 222712564 222712564 1 +      
ENSG00000162819 E004 0.0000000       1 222712565 222712566 2 +      
ENSG00000162819 E005 0.0000000       1 222712567 222712574 8 +      
ENSG00000162819 E006 0.0000000       1 222712575 222712615 41 +      
ENSG00000162819 E007 19.3139271 7.003598e-04 0.0026274393 0.031220162 1 222712616 222712942 327 + 1.401 1.202 -0.698
ENSG00000162819 E008 0.2451451 1.635384e-02 0.9766806812   1 222713277 222713320 44 + 0.097 0.094 -0.052
ENSG00000162819 E009 0.9586193 5.801195e-02 0.1577746135 0.424511261 1 222713321 222713368 48 + 0.397 0.170 -1.636
ENSG00000162819 E010 0.9664882 1.280162e-01 0.5189375684 0.773736732 1 222713369 222713375 7 + 0.351 0.236 -0.788
ENSG00000162819 E011 0.9664882 1.280162e-01 0.5189375684 0.773736732 1 222713376 222713378 3 + 0.351 0.236 -0.788
ENSG00000162819 E012 1.0936245 3.638990e-02 0.7158836533 0.885473985 1 222713379 222713380 2 + 0.351 0.293 -0.373
ENSG00000162819 E013 1.8293761 8.100733e-03 0.7458265959 0.899515008 1 222713381 222713390 10 + 0.476 0.429 -0.244
ENSG00000162819 E014 2.3293319 6.078740e-03 0.8828050640 0.960560720 1 222713391 222713400 10 + 0.511 0.532 0.100
ENSG00000162819 E015 4.1546795 3.354781e-03 0.6557044620 0.855688849 1 222713401 222713416 16 + 0.739 0.685 -0.222
ENSG00000162819 E016 7.7748320 3.220538e-02 0.1465347177 0.407633767 1 222713588 222713985 398 + 0.844 1.016 0.649
ENSG00000162819 E017 0.9890203 1.201930e-02 0.5151995882 0.771420439 1 222715075 222715144 70 + 0.242 0.343 0.685
ENSG00000162819 E018 1.7425542 1.000191e-02 0.1247284102 0.374371895 1 222715145 222715269 125 + 0.300 0.532 1.270
ENSG00000162819 E019 22.9713769 1.168234e-03 0.0013576460 0.018957358 1 222715684 222715800 117 + 1.472 1.274 -0.688
ENSG00000162819 E020 0.3810317 2.849760e-02 0.1124553262   1 222717858 222718094 237 + 0.000 0.236 10.869
ENSG00000162819 E021 29.9278424 1.833780e-03 0.1450836669 0.405437435 1 222718925 222719031 107 + 1.530 1.450 -0.276
ENSG00000162819 E022 29.5953332 8.845655e-03 0.4284301323 0.706927843 1 222719263 222719359 97 + 1.511 1.461 -0.171
ENSG00000162819 E023 30.4601341 1.264056e-02 0.7345770219 0.894670124 1 222722419 222722514 96 + 1.510 1.485 -0.086
ENSG00000162819 E024 13.6734184 1.210773e-02 0.5224527448 0.775952982 1 222724092 222724099 8 + 1.196 1.138 -0.206
ENSG00000162819 E025 26.2175587 5.539614e-04 0.0658600283 0.258511753 1 222724100 222724164 65 + 1.486 1.382 -0.362
ENSG00000162819 E026 33.1673430 2.303420e-03 0.0327671423 0.171659853 1 222725450 222725555 106 + 1.590 1.475 -0.393
ENSG00000162819 E027 26.1856451 5.114772e-04 0.5856896344 0.816114086 1 222727168 222727257 90 + 1.450 1.419 -0.106
ENSG00000162819 E028 1.2627740 4.186542e-01 0.1059351124 0.340799544 1 222728549 222728742 194 + 0.097 0.500 3.118
ENSG00000162819 E029 25.0196458 5.350512e-04 0.1466426352 0.407681644 1 222728743 222728828 86 + 1.457 1.373 -0.292
ENSG00000162819 E030 29.2525048 4.805706e-04 0.7258402739 0.890119812 1 222729620 222729701 82 + 1.490 1.471 -0.064
ENSG00000162819 E031 52.5439107 3.066343e-04 0.3278725339 0.620385814 1 222730027 222730177 151 + 1.706 1.747 0.137
ENSG00000162819 E032 55.4555733 6.051400e-04 0.4645465079 0.733993009 1 222731357 222731516 160 + 1.735 1.765 0.102
ENSG00000162819 E033 629.7464984 9.917355e-05 0.0001106221 0.002586169 1 222732628 222735196 2569 + 2.783 2.814 0.103

Help

Please Click HERE to learn more details about the results from DEXseq.