ENSG00000162923

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000480676 ENSG00000162923 No_inf pgKDN_inf WDR26 protein_coding protein_coding 142.8663 135.1329 157.826 2.067651 2.150893 0.2239409 16.972088 23.93461 13.810589 2.2594356 1.776255 -0.7928822 0.1204750 0.176550 0.087700 -0.088850 0.064974925 0.002763244 FALSE TRUE
ENST00000651911 ENSG00000162923 No_inf pgKDN_inf WDR26 protein_coding protein_coding 142.8663 135.1329 157.826 2.067651 2.150893 0.2239409 34.674426 32.20934 43.128986 0.6314832 3.131840 0.4210652 0.2411333 0.238600 0.273700 0.035100 0.818291577 0.002763244 FALSE TRUE
ENST00000678917 ENSG00000162923 No_inf pgKDN_inf WDR26 protein_coding protein_coding 142.8663 135.1329 157.826 2.067651 2.150893 0.2239409 9.996095 19.77768 2.411581 1.5006173 2.411581 -3.0305811 0.0731250 0.146175 0.015050 -0.131125 0.002763244 0.002763244 FALSE TRUE
ENST00000704632 ENSG00000162923 No_inf pgKDN_inf WDR26 protein_coding nonsense_mediated_decay 142.8663 135.1329 157.826 2.067651 2.150893 0.2239409 19.394476 4.59963 29.311487 2.2854479 2.049126 2.6692355 0.1329500 0.033875 0.186325 0.152450 0.030916577 0.002763244 TRUE TRUE
MSTRG.2759.9 ENSG00000162923 No_inf pgKDN_inf WDR26 protein_coding   142.8663 135.1329 157.826 2.067651 2.150893 0.2239409 44.578887 39.25617 50.582680 1.0885179 5.169261 0.3656418 0.3114417 0.290900 0.319625 0.028725 0.849133118 0.002763244 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000162923 E001 1.7611510 2.293964e-01 4.050873e-02 1.951932e-01 1 224385146 224385160 15 - 0.174 0.593 2.565
ENSG00000162923 E002 6.0791804 1.365550e-02 2.569880e-02 1.480494e-01 1 224385161 224385183 23 - 0.694 0.955 1.025
ENSG00000162923 E003 119.8544233 1.394550e-04 5.063880e-24 1.909897e-21 1 224385184 224385665 482 - 1.908 2.197 0.969
ENSG00000162923 E004 261.6056326 7.763278e-05 2.081194e-29 1.194118e-26 1 224385666 224386502 837 - 2.295 2.508 0.711
ENSG00000162923 E005 691.2807502 4.434134e-05 3.039020e-14 4.849305e-12 1 224386503 224389135 2633 - 2.794 2.878 0.278
ENSG00000162923 E006 31.3152990 3.466143e-03 5.797561e-01 8.123717e-01 1 224389136 224389147 12 - 1.525 1.493 -0.110
ENSG00000162923 E007 28.4135142 1.728550e-03 9.196825e-01 9.749427e-01 1 224389148 224389149 2 - 1.471 1.465 -0.019
ENSG00000162923 E008 41.9558513 4.446180e-04 4.760589e-01 7.426965e-01 1 224389150 224389183 34 - 1.649 1.617 -0.112
ENSG00000162923 E009 80.0557641 1.157409e-03 6.499046e-01 8.525552e-01 1 224389184 224389253 70 - 1.917 1.901 -0.055
ENSG00000162923 E010 679.0847231 5.975764e-04 4.792711e-01 7.450776e-01 1 224389254 224389832 579 - 2.827 2.837 0.033
ENSG00000162923 E011 104.9990206 1.393921e-04 8.641210e-01 9.529443e-01 1 224389833 224389860 28 - 2.022 2.027 0.018
ENSG00000162923 E012 234.2492959 1.260495e-04 9.866285e-02 3.277257e-01 1 224393828 224394013 186 - 2.388 2.355 -0.108
ENSG00000162923 E013 1.8502740 9.601193e-03 4.610746e-01 7.320564e-01 1 224397167 224397326 160 - 0.394 0.504 0.566
ENSG00000162923 E014 2.2307750 1.306237e-02 1.735421e-01 4.467907e-01 1 224397727 224398096 370 - 0.394 0.593 0.981
ENSG00000162923 E015 207.7819237 1.314187e-04 1.632605e-04 3.541951e-03 1 224398097 224398226 130 - 2.359 2.280 -0.264
ENSG00000162923 E016 165.2466325 1.196488e-04 1.745893e-02 1.158577e-01 1 224398515 224398593 79 - 2.248 2.193 -0.186
ENSG00000162923 E017 231.9644272 7.688450e-05 4.098990e-02 1.965348e-01 1 224398889 224399024 136 - 2.387 2.347 -0.134
ENSG00000162923 E018 90.4472836 1.718806e-04 1.521629e-01 4.159108e-01 1 224399025 224399034 10 - 1.984 1.939 -0.152
ENSG00000162923 E019 184.0997357 1.534079e-04 8.059009e-03 6.947607e-02 1 224400950 224401069 120 - 2.297 2.238 -0.198
ENSG00000162923 E020 5.4169911 2.784515e-02 4.593648e-01 7.310475e-01 1 224402004 224402109 106 - 0.755 0.850 0.377
ENSG00000162923 E021 177.7557597 1.054260e-04 9.255746e-04 1.415767e-02 1 224404430 224404570 141 - 2.289 2.215 -0.250
ENSG00000162923 E022 184.4048065 1.001990e-04 8.759485e-03 7.353175e-02 1 224411427 224411562 136 - 2.297 2.239 -0.194
ENSG00000162923 E023 41.0894331 6.483504e-03 4.530995e-01 7.259014e-01 1 224411563 224411565 3 - 1.645 1.604 -0.140
ENSG00000162923 E024 32.2377288 3.129456e-03 1.407262e-16 2.800711e-14 1 224411566 224413252 1687 - 1.184 1.696 1.767
ENSG00000162923 E025 2.7571922 5.092867e-03 2.410344e-03 2.931217e-02 1 224413253 224413335 83 - 0.298 0.730 2.151
ENSG00000162923 E026 124.8346401 1.796807e-04 1.227152e-03 1.752786e-02 1 224418260 224418372 113 - 2.143 2.055 -0.294
ENSG00000162923 E027 64.5001644 6.791502e-04 3.894450e-03 4.165872e-02 1 224418373 224418398 26 - 1.870 1.759 -0.376
ENSG00000162923 E028 60.9586114 1.072743e-03 7.108239e-03 6.370485e-02 1 224418399 224418416 18 - 1.845 1.736 -0.367
ENSG00000162923 E029 1.0066778 1.168023e-02 2.784317e-02 1.558171e-01 1 224419445 224419517 73 - 0.096 0.432 2.788
ENSG00000162923 E030 75.9036697 1.991794e-04 7.395469e-01 8.968346e-01 1 224419518 224419548 31 - 1.891 1.880 -0.038
ENSG00000162923 E031 66.1920884 2.667996e-04 5.861716e-01 8.164434e-01 1 224419549 224419561 13 - 1.837 1.817 -0.067
ENSG00000162923 E032 87.6737368 3.297437e-04 4.379986e-02 2.044044e-01 1 224419562 224419615 54 - 1.981 1.915 -0.221
ENSG00000162923 E033 122.8495726 1.262154e-04 5.326542e-04 9.173949e-03 1 224424518 224424654 137 - 2.139 2.045 -0.316
ENSG00000162923 E034 1.7347130 2.357009e-02 3.138986e-01 6.070637e-01 1 224424655 224424719 65 - 0.349 0.504 0.829
ENSG00000162923 E035 12.4298126 1.099143e-03 8.113916e-05 1.994603e-03 1 224429297 224431476 2180 - 0.924 1.256 1.203
ENSG00000162923 E036 15.2394583 1.975282e-02 2.234929e-01 5.111090e-01 1 224431477 224431524 48 - 1.267 1.150 -0.415
ENSG00000162923 E037 64.0764773 6.036597e-04 2.054743e-02 1.291012e-01 1 224431525 224431581 57 - 1.857 1.768 -0.301
ENSG00000162923 E038 81.2686192 8.904633e-03 7.120692e-02 2.703892e-01 1 224431682 224431781 100 - 1.960 1.869 -0.307
ENSG00000162923 E039 1.7591121 7.674724e-03 5.820093e-03 5.522781e-02 1 224433096 224433265 170 - 0.174 0.593 2.566
ENSG00000162923 E040 229.1524871 8.924247e-05 2.171897e-11 2.361676e-09 1 224433684 224434797 1114 - 2.426 2.293 -0.444
ENSG00000162923 E041 0.2441403 1.658146e-02 9.916705e-01   1 224435717 224435891 175 - 0.096 0.095 -0.019
ENSG00000162923 E042 0.1170040 1.172069e-02 5.308298e-01   1 224436821 224437033 213 - 0.096 0.000 -8.250

Help

Please Click HERE to learn more details about the results from DEXseq.