ENSG00000163444

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000367242 ENSG00000163444 No_inf pgKDN_inf TMEM183A protein_coding protein_coding 58.82414 56.65852 62.34687 3.60335 2.405141 0.138001 26.989047 19.370271 32.9176315 2.6663708 1.3491440 0.7647100 0.46142500 0.353550 0.532200 0.178650 0.309235896 0.009798816 FALSE TRUE
ENST00000468449 ENSG00000163444 No_inf pgKDN_inf TMEM183A protein_coding protein_coding_CDS_not_defined 58.82414 56.65852 62.34687 3.60335 2.405141 0.138001 4.805618 8.683419 3.8739735 3.3658784 3.8739735 -1.1623903 0.08000833 0.151875 0.055800 -0.096075 0.268055512 0.009798816 FALSE TRUE
MSTRG.2529.2 ENSG00000163444 No_inf pgKDN_inf TMEM183A protein_coding   58.82414 56.65852 62.34687 3.60335 2.405141 0.138001 5.426836 5.847718 4.6611895 0.8694062 0.6802954 -0.3265488 0.09280833 0.102250 0.075350 -0.026900 0.822701815 0.009798816 FALSE TRUE
MSTRG.2529.3 ENSG00000163444 No_inf pgKDN_inf TMEM183A protein_coding   58.82414 56.65852 62.34687 3.60335 2.405141 0.138001 4.331369 10.778478 0.4441533 4.6653976 0.4441533 -4.5701681 0.07203333 0.178875 0.006400 -0.172475 0.104574841 0.009798816 FALSE TRUE
MSTRG.2529.5 ENSG00000163444 No_inf pgKDN_inf TMEM183A protein_coding   58.82414 56.65852 62.34687 3.60335 2.405141 0.138001 10.462385 2.012081 15.4913257 2.0120814 1.9998739 2.9384786 0.17739167 0.039450 0.251775 0.212325 0.009798816 0.009798816 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000163444 E001 0.4825515 0.0269021252 3.385265e-01   1 203007258 203007344 87 + 0.235 0.097 -1.514
ENSG00000163444 E002 0.3642603 0.2239014184 6.533192e-01   1 203007345 203007361 17 + 0.170 0.097 -0.930
ENSG00000163444 E003 0.3642603 0.2239014184 6.533192e-01   1 203007362 203007373 12 + 0.170 0.097 -0.930
ENSG00000163444 E004 0.6265274 0.1470968491 2.078705e-01 4.915723e-01 1 203007374 203007377 4 + 0.093 0.302 2.071
ENSG00000163444 E005 3.6635980 0.0055661033 7.855220e-01 9.173977e-01 1 203007378 203007402 25 + 0.683 0.654 -0.122
ENSG00000163444 E006 30.2750736 0.0004753840 3.230258e-03 3.649366e-02 1 203007403 203007574 172 + 1.563 1.416 -0.505
ENSG00000163444 E007 2.4607413 0.0065758182 6.084675e-01 8.294984e-01 1 203007575 203007773 199 + 0.498 0.575 0.360
ENSG00000163444 E008 36.7066649 0.0004878100 2.515609e-04 5.047503e-03 1 203007774 203007863 90 + 1.653 1.486 -0.570
ENSG00000163444 E009 37.6450396 0.0003730419 1.752373e-02 1.161372e-01 1 203008643 203008739 97 + 1.636 1.533 -0.352
ENSG00000163444 E010 29.5325774 0.0004784971 2.310788e-01 5.195381e-01 1 203008740 203008810 71 + 1.512 1.456 -0.192
ENSG00000163444 E011 5.4836303 0.0179938338 5.662023e-01 8.046092e-01 1 203014889 203014891 3 + 0.843 0.779 -0.251
ENSG00000163444 E012 42.5242914 0.0003554541 3.573626e-01 6.469872e-01 1 203014892 203015048 157 + 1.655 1.622 -0.112
ENSG00000163444 E013 8.2992032 0.0133368769 6.495409e-03 5.974137e-02 1 203015049 203015229 181 + 0.796 1.089 1.103
ENSG00000163444 E014 20.0466107 0.0071614118 1.416935e-04 3.157891e-03 1 203015230 203015827 598 + 1.158 1.441 0.992
ENSG00000163444 E015 2.1042025 0.0073578104 2.046389e-01 4.876506e-01 1 203015828 203015839 12 + 0.386 0.575 0.945
ENSG00000163444 E016 7.1143510 0.0432771837 8.462279e-01 9.453871e-01 1 203015840 203015959 120 + 0.886 0.931 0.170
ENSG00000163444 E017 47.2751613 0.0003760750 2.649807e-01 5.580426e-01 1 203015960 203016140 181 + 1.703 1.664 -0.131
ENSG00000163444 E018 2.3019500 0.0071747641 2.855515e-01 5.791784e-01 1 203017756 203017758 3 + 0.587 0.440 -0.707
ENSG00000163444 E019 10.2992382 0.0015092607 7.151637e-01 8.852006e-01 1 203017759 203017919 161 + 1.033 1.071 0.139
ENSG00000163444 E020 2.9312439 0.0049025474 7.441304e-01 8.987349e-01 1 203018481 203018500 20 + 0.613 0.575 -0.170
ENSG00000163444 E021 3.2990662 0.0206650573 9.150045e-01 9.733292e-01 1 203018501 203018561 61 + 0.638 0.629 -0.036
ENSG00000163444 E022 0.4975013 0.0151957490 3.041361e-01   1 203019241 203019288 48 + 0.093 0.244 1.656
ENSG00000163444 E023 0.8712646 0.0316248877 2.448782e-01 5.352421e-01 1 203020793 203020948 156 + 0.170 0.353 1.393
ENSG00000163444 E024 76.3104340 0.0021353311 1.793633e-06 7.732838e-05 1 203022855 203024848 1994 + 1.792 1.965 0.584

Help

Please Click HERE to learn more details about the results from DEXseq.