ENSG00000163785

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000460933 ENSG00000163785 No_inf pgKDN_inf RYK protein_coding protein_coding 25.26682 25.09693 26.01689 0.9350491 2.289695 0.05191714 13.089481 14.773089 14.903112 0.9165096 1.296106 0.01263354 0.5235250 0.593100 0.593225 0.000125 1.000000e+00 2.576917e-07 FALSE TRUE
ENST00000464879 ENSG00000163785 No_inf pgKDN_inf RYK protein_coding retained_intron 25.26682 25.09693 26.01689 0.9350491 2.289695 0.05191714 3.000404 4.102281 2.797563 1.2739911 1.480855 -0.55062067 0.1137667 0.160725 0.098250 -0.062475 7.923516e-01 2.576917e-07   FALSE
ENST00000480381 ENSG00000163785 No_inf pgKDN_inf RYK protein_coding retained_intron 25.26682 25.09693 26.01689 0.9350491 2.289695 0.05191714 3.192281 4.874120 1.265965 0.2039112 0.840377 -1.93651019 0.1248667 0.194350 0.042325 -0.152025 1.263310e-01 2.576917e-07 FALSE FALSE
ENST00000623711 ENSG00000163785 No_inf pgKDN_inf RYK protein_coding protein_coding 25.26682 25.09693 26.01689 0.9350491 2.289695 0.05191714 4.056595 0.000000 6.369441 0.0000000 2.029719 9.31728612 0.1651583 0.000000 0.240400 0.240400 2.576917e-07 2.576917e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000163785 E001 0.0000000       3 134065303 134065790 488 -      
ENSG00000163785 E002 0.0000000       3 134065956 134066111 156 -      
ENSG00000163785 E003 0.0000000       3 134075035 134075213 179 -      
ENSG00000163785 E004 0.5862732 0.1944284105 6.029867e-02 0.246441033 3 134157133 134157133 1 - 0.324 0.000 -11.272
ENSG00000163785 E005 132.9497014 0.0001884291 1.327517e-03 0.018655110 3 134157134 134158264 1131 - 2.092 2.161 0.231
ENSG00000163785 E006 17.9161605 0.0081028696 6.204799e-01 0.835892604 3 134159237 134159282 46 - 1.293 1.256 -0.131
ENSG00000163785 E007 20.7767935 0.0007123936 1.145992e-01 0.356755704 3 134159283 134159373 91 - 1.381 1.281 -0.350
ENSG00000163785 E008 18.2070798 0.0007915583 6.362317e-01 0.844885635 3 134175609 134175702 94 - 1.268 1.299 0.109
ENSG00000163785 E009 14.7345568 0.0009827084 6.842230e-02 0.264002801 3 134175703 134175768 66 - 1.128 1.262 0.477
ENSG00000163785 E010 19.4153095 0.0007359541 8.302218e-01 0.938488922 3 134175930 134176039 110 - 1.303 1.316 0.048
ENSG00000163785 E011 18.7443376 0.0008632934 2.922036e-01 0.585663058 3 134177941 134178073 133 - 1.326 1.256 -0.247
ENSG00000163785 E012 3.8111923 0.1622652256 3.817204e-01 0.668084972 3 134178074 134181672 3599 - 0.589 0.768 0.754
ENSG00000163785 E013 10.2992283 0.0074760620 8.274242e-02 0.296402063 3 134183002 134183071 70 - 1.121 0.959 -0.590
ENSG00000163785 E014 1.6121775 0.0775140733 1.220099e-01 0.369571533 3 134183072 134183403 332 - 0.276 0.535 1.454
ENSG00000163785 E015 14.1295105 0.0102654391 7.026122e-01 0.879023149 3 134188837 134188923 87 - 1.194 1.161 -0.116
ENSG00000163785 E016 17.2300997 0.0009492601 8.041435e-01 0.927278648 3 134191849 134191974 126 - 1.252 1.268 0.058
ENSG00000163785 E017 4.7564329 0.0029775023 8.525248e-01 0.947905877 3 134191975 134191983 9 - 0.769 0.748 -0.088
ENSG00000163785 E018 16.0715901 0.0029971371 5.448630e-01 0.791082024 3 134195082 134195182 101 - 1.252 1.207 -0.156
ENSG00000163785 E019 3.3899822 0.0239655533 4.910903e-05 0.001310154 3 134195183 134195339 157 - 0.276 0.858 2.807
ENSG00000163785 E020 1.9823247 0.0213728936 6.515362e-02 0.257053862 3 134202537 134202729 193 - 0.324 0.599 1.422
ENSG00000163785 E021 17.2957695 0.0029435741 6.195350e-01 0.835419433 3 134202730 134202874 145 - 1.278 1.242 -0.125
ENSG00000163785 E022 10.0903739 0.0519588173 4.787986e-01 0.744751774 3 134207472 134207525 54 - 1.083 0.996 -0.316
ENSG00000163785 E023 14.4894382 0.0016620939 7.753071e-04 0.012325261 3 134209695 134209829 135 - 1.293 1.030 -0.938
ENSG00000163785 E024 10.3083785 0.0016366793 1.087142e-01 0.346086017 3 134211508 134211607 100 - 1.113 0.972 -0.517
ENSG00000163785 E025 10.1936705 0.0013732828 1.294734e-01 0.381716570 3 134222418 134222539 122 - 1.106 0.972 -0.490
ENSG00000163785 E026 12.2923256 0.0012159148 3.619751e-01 0.651300524 3 134250423 134250919 497 - 1.156 1.082 -0.265

Help

Please Click HERE to learn more details about the results from DEXseq.