ENSG00000164002

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358527 ENSG00000164002 No_inf pgKDN_inf EXO5 protein_coding protein_coding 114.3062 91.10835 128.386 2.31949 0.8090391 0.4947872 10.00253 3.070632 13.588333 2.3582994 4.1106027 2.1421313 0.08181667 0.032375 0.105600 0.073225 0.26608453 0.02035071 FALSE TRUE
ENST00000372703 ENSG00000164002 No_inf pgKDN_inf EXO5 protein_coding protein_coding 114.3062 91.10835 128.386 2.31949 0.8090391 0.4947872 11.60355 14.047261 9.247877 0.7770468 0.5008897 -0.6025623 0.10662500 0.154350 0.072025 -0.082325 0.03114304 0.02035071 FALSE TRUE
ENST00000415550 ENSG00000164002 No_inf pgKDN_inf EXO5 protein_coding protein_coding 114.3062 91.10835 128.386 2.31949 0.8090391 0.4947872 19.09668 13.844898 25.015233 1.7630021 2.3399398 0.8529875 0.16498333 0.151700 0.195000 0.043300 0.74445273 0.02035071 FALSE TRUE
ENST00000418186 ENSG00000164002 No_inf pgKDN_inf EXO5 protein_coding protein_coding 114.3062 91.10835 128.386 2.31949 0.8090391 0.4947872 13.56945 5.264340 10.376041 5.2643400 5.1540011 0.9775833 0.11440000 0.058800 0.081125 0.022325 0.53093622 0.02035071 FALSE TRUE
ENST00000420209 ENSG00000164002 No_inf pgKDN_inf EXO5 protein_coding protein_coding 114.3062 91.10835 128.386 2.31949 0.8090391 0.4947872 22.09237 12.096118 36.869097 1.6887680 3.5517358 1.6070670 0.18712500 0.132925 0.287475 0.154550 0.02035071 0.02035071 FALSE TRUE
ENST00000443729 ENSG00000164002 No_inf pgKDN_inf EXO5 protein_coding protein_coding 114.3062 91.10835 128.386 2.31949 0.8090391 0.4947872 18.51901 19.163879 13.377389 4.6170591 3.7904494 -0.5182676 0.16715000 0.212075 0.104000 -0.108075 0.41061537 0.02035071 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000164002 E001 0.2458395 0.0161921009 9.030831e-01   1 40508679 40508733 55 + 0.090 0.101 0.191
ENSG00000164002 E002 1.5878128 0.0097742319 9.963188e-01 1.000000e+00 1 40508734 40508740 7 + 0.416 0.410 -0.031
ENSG00000164002 E003 2.2954308 0.0115874149 2.085297e-01 4.926127e-01 1 40508741 40508746 6 + 0.600 0.410 -0.924
ENSG00000164002 E004 2.8939137 0.0137073649 1.014581e-01 3.326452e-01 1 40508747 40508753 7 + 0.690 0.452 -1.089
ENSG00000164002 E005 3.8740925 0.0058641662 1.873796e-01 4.654628e-01 1 40508754 40508760 7 + 0.764 0.588 -0.742
ENSG00000164002 E006 4.6002122 0.0031471616 1.418806e-01 4.007639e-01 1 40508761 40508766 6 + 0.828 0.643 -0.752
ENSG00000164002 E007 6.4086896 0.0059223704 4.426168e-02 2.057584e-01 1 40508767 40508774 8 + 0.966 0.736 -0.891
ENSG00000164002 E008 19.5100113 0.0008867287 4.537679e-01 7.264327e-01 1 40508775 40508797 23 + 1.339 1.280 -0.208
ENSG00000164002 E009 20.2258103 0.0007537426 3.108760e-01 6.040127e-01 1 40508798 40508805 8 + 1.362 1.286 -0.264
ENSG00000164002 E010 29.7918187 0.0058219590 8.773860e-01 9.584351e-01 1 40508806 40508877 72 + 1.498 1.478 -0.070
ENSG00000164002 E011 11.1732169 0.0351455080 2.575039e-01 5.497671e-01 1 40508878 40508889 12 + 1.026 1.140 0.414
ENSG00000164002 E012 10.9209319 0.0639851282 4.368686e-01 7.132997e-01 1 40508890 40508908 19 + 1.026 1.124 0.354
ENSG00000164002 E013 14.8854130 0.0028372096 4.354359e-06 1.670327e-04 1 40508909 40509084 176 + 0.997 1.346 1.246
ENSG00000164002 E014 25.8867448 0.0005165680 1.233065e-08 8.659394e-07 1 40509085 40509349 265 + 1.243 1.566 1.119
ENSG00000164002 E015 12.2562944 0.0093044779 2.765307e-01 5.700605e-01 1 40509350 40509450 101 + 1.079 1.164 0.307
ENSG00000164002 E016 13.8121232 0.0010186938 7.174245e-01 8.862883e-01 1 40509451 40509457 7 + 1.162 1.180 0.064
ENSG00000164002 E017 53.6780273 0.0003012958 4.465512e-01 7.209598e-01 1 40509458 40509625 168 + 1.757 1.716 -0.138
ENSG00000164002 E018 14.5261971 0.0009687908 2.034880e-02 1.283169e-01 1 40509626 40509732 107 + 1.103 1.268 0.585
ENSG00000164002 E019 21.8581376 0.0006377365 9.420142e-01 9.836326e-01 1 40509733 40509790 58 + 1.366 1.351 -0.051
ENSG00000164002 E020 421.5835545 0.0025420821 1.796899e-02 1.181743e-01 1 40514515 40516038 1524 + 2.645 2.604 -0.135
ENSG00000164002 E021 4.4194068 0.0613346176 5.416919e-01 7.892699e-01 1 40531245 40531512 268 + 0.690 0.776 0.352

Help

Please Click HERE to learn more details about the results from DEXseq.