ENSG00000164180

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000296595 ENSG00000164180 No_inf pgKDN_inf TMEM161B protein_coding protein_coding 11.32332 8.221314 12.93152 0.2713849 1.004961 0.6528121 1.3125024 0.0000000 3.9375073 0.00000000 2.48586711 8.6247981 0.11218333 0.000000 0.336550 0.336550 0.64130474 0.02023715 FALSE TRUE
ENST00000510089 ENSG00000164180 No_inf pgKDN_inf TMEM161B protein_coding nonsense_mediated_decay 11.32332 8.221314 12.93152 0.2713849 1.004961 0.6528121 1.0270820 1.4808569 0.7360775 0.09222206 0.06625864 -0.9987444 0.10218333 0.180750 0.058275 -0.122475 0.21640972 0.02023715 TRUE FALSE
ENST00000511218 ENSG00000164180 No_inf pgKDN_inf TMEM161B protein_coding protein_coding 11.32332 8.221314 12.93152 0.2713849 1.004961 0.6528121 0.8024185 0.0000000 1.0594380 0.00000000 1.05943804 6.7407091 0.05650833 0.000000 0.066675 0.066675 0.87301693 0.02023715 FALSE TRUE
MSTRG.23186.5 ENSG00000164180 No_inf pgKDN_inf TMEM161B protein_coding   11.32332 8.221314 12.93152 0.2713849 1.004961 0.6528121 3.3964044 0.8555134 4.4219046 0.85551340 1.55488878 2.3562988 0.27130833 0.098325 0.330600 0.232275 0.36034159 0.02023715 FALSE TRUE
MSTRG.23186.7 ENSG00000164180 No_inf pgKDN_inf TMEM161B protein_coding   11.32332 8.221314 12.93152 0.2713849 1.004961 0.6528121 3.8528314 5.0726232 1.3894327 0.82655165 1.38943267 -1.8607312 0.37838333 0.625350 0.111325 -0.514025 0.02023715 0.02023715 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000164180 E001 2.3663445 0.0392961041 1.772726e-02 1.171694e-01 5 88189633 88190261 629 - 0.321 0.685 1.814
ENSG00000164180 E002 0.1170040 0.0117507697 6.727995e-01   5 88195047 88195168 122 - 0.086 0.000 -11.681
ENSG00000164180 E003 0.0000000       5 88195169 88195205 37 -      
ENSG00000164180 E004 0.0000000       5 88195206 88195206 1 -      
ENSG00000164180 E005 1.5524993 0.0141258412 2.788537e-02 1.559002e-01 5 88195207 88195319 113 - 0.532 0.190 -2.131
ENSG00000164180 E006 35.7937014 0.0014700172 3.962196e-01 6.809687e-01 5 88195320 88195827 508 - 1.545 1.586 0.141
ENSG00000164180 E007 23.3507812 0.0006185058 2.114561e-01 4.964374e-01 5 88195828 88196116 289 - 1.417 1.345 -0.250
ENSG00000164180 E008 20.8002292 0.0007307753 2.704273e-01 5.640945e-01 5 88196117 88196349 233 - 1.367 1.299 -0.235
ENSG00000164180 E009 7.3321380 0.0078409638 7.320430e-01 8.935007e-01 5 88196350 88196375 26 - 0.903 0.938 0.136
ENSG00000164180 E010 13.1663319 0.0011012848 8.530517e-01 9.481594e-01 5 88196376 88196488 113 - 1.156 1.143 -0.048
ENSG00000164180 E011 9.1515907 0.0038977228 8.718687e-01 9.560881e-01 5 88197669 88197765 97 - 0.998 1.014 0.058
ENSG00000164180 E012 9.0856852 0.0015593382 9.197546e-07 4.332406e-05 5 88197766 88198975 1210 - 0.730 1.191 1.734
ENSG00000164180 E013 8.7187627 0.0017040846 9.363307e-02 3.181784e-01 5 88198976 88199069 94 - 1.052 0.895 -0.582
ENSG00000164180 E014 8.9325021 0.0085497005 2.473520e-02 1.445800e-01 5 88199070 88199150 81 - 1.084 0.864 -0.820
ENSG00000164180 E015 21.2126267 0.0008239987 1.947878e-10 1.876015e-08 5 88199151 88202683 3533 - 1.114 1.516 1.405
ENSG00000164180 E016 1.1157784 0.0117054179 1.840765e-01 4.611875e-01 5 88202684 88202942 259 - 0.219 0.423 1.329
ENSG00000164180 E017 0.1271363 0.0123161512 4.282363e-01   5 88202943 88202961 19 - 0.000 0.105 11.569
ENSG00000164180 E018 8.4400630 0.0018550238 6.281600e-03 5.836207e-02 5 88202962 88203075 114 - 1.076 0.812 -0.993
ENSG00000164180 E019 0.3707734 0.0165347322 4.534778e-01   5 88205754 88205800 47 - 0.086 0.190 1.328
ENSG00000164180 E020 0.6081146 0.0148034283 8.434150e-01 9.440435e-01 5 88205801 88205813 13 - 0.219 0.190 -0.257
ENSG00000164180 E021 7.9467859 0.0209788132 5.993371e-03 5.645240e-02 5 88205814 88205954 141 - 1.068 0.753 -1.199
ENSG00000164180 E022 0.1268540 0.0124523184 4.279858e-01   5 88206420 88206438 19 - 0.000 0.105 11.568
ENSG00000164180 E023 6.4129210 0.0022567999 1.215767e-01 3.691240e-01 5 88206439 88206499 61 - 0.937 0.774 -0.631
ENSG00000164180 E024 4.0245809 0.0042123339 9.057815e-01 9.699483e-01 5 88207029 88207034 6 - 0.693 0.709 0.065
ENSG00000164180 E025 6.2279073 0.0023771156 7.039981e-01 8.796347e-01 5 88207035 88207142 108 - 0.839 0.880 0.159
ENSG00000164180 E026 3.4119055 0.0042397423 8.696501e-01 9.551341e-01 5 88207143 88207180 38 - 0.653 0.633 -0.087
ENSG00000164180 E027 4.3693296 0.0131317318 3.332464e-01 6.252674e-01 5 88220563 88220614 52 - 0.780 0.659 -0.495
ENSG00000164180 E028 8.2828856 0.0016522572 7.691867e-01 9.107843e-01 5 88220615 88220719 105 - 0.979 0.952 -0.099
ENSG00000164180 E029 0.0000000       5 88221301 88221471 171 -      
ENSG00000164180 E030 0.1186381 0.0118163599 6.729133e-01   5 88221674 88221760 87 - 0.086 0.000 -11.681
ENSG00000164180 E031 7.3453770 0.0020716642 7.754550e-03 6.766330e-02 5 88225769 88225866 98 - 1.026 0.753 -1.043
ENSG00000164180 E032 0.0000000       5 88228441 88228444 4 -      
ENSG00000164180 E033 3.6554208 0.0596819797 8.679903e-01 9.547298e-01 5 88228445 88228458 14 - 0.673 0.660 -0.058
ENSG00000164180 E034 5.6289643 0.0273475990 6.781908e-01 8.667744e-01 5 88228459 88228528 70 - 0.795 0.847 0.203
ENSG00000164180 E035 4.2737618 0.0034744635 8.759470e-01 9.578356e-01 5 88240813 88240916 104 - 0.712 0.731 0.081
ENSG00000164180 E036 0.0000000       5 88250651 88251037 387 -      
ENSG00000164180 E037 0.0000000       5 88259232 88259363 132 -      
ENSG00000164180 E038 2.9135213 0.0053503898 4.978287e-01 7.584277e-01 5 88268721 88268787 67 - 0.631 0.540 -0.409
ENSG00000164180 E039 1.3429233 0.0094188830 9.438771e-01 9.844702e-01 5 88268788 88269070 283 - 0.364 0.375 0.065
ENSG00000164180 E040 0.1268540 0.0124523184 4.279858e-01   5 88269364 88269476 113 - 0.000 0.105 11.568

Help

Please Click HERE to learn more details about the results from DEXseq.