ENSG00000164466

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000321442 ENSG00000164466 No_inf pgKDN_inf SFXN1 protein_coding protein_coding 16.10321 5.534072 22.66013 0.4417305 1.48545 2.031775 9.9154030 4.6199718 12.4727476 0.2402094 0.4963912 1.4308602 0.6801167 0.841425 0.558550 -0.282875 0.04953226 0.04953226 FALSE TRUE
ENST00000502393 ENSG00000164466 No_inf pgKDN_inf SFXN1 protein_coding protein_coding 16.10321 5.534072 22.66013 0.4417305 1.48545 2.031775 0.8868631 0.0000000 1.0151984 0.0000000 1.0151984 6.6797593 0.0388250 0.000000 0.051650 0.051650 1.00000000 0.04953226 FALSE TRUE
ENST00000506963 ENSG00000164466 No_inf pgKDN_inf SFXN1 protein_coding protein_coding 16.10321 5.534072 22.66013 0.4417305 1.48545 2.031775 1.5254513 0.2340465 0.2157377 0.2340465 0.2157377 -0.1125091 0.0865250 0.036525 0.010975 -0.025550 0.84019963 0.04953226 FALSE FALSE
ENST00000507017 ENSG00000164466 No_inf pgKDN_inf SFXN1 protein_coding protein_coding 16.10321 5.534072 22.66013 0.4417305 1.48545 2.031775 1.7298784 0.0000000 5.1896352 0.0000000 1.7612851 9.0222666 0.0734500 0.000000 0.220350 0.220350 0.09851132 0.04953226 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000164466 E001 0.0000000       5 175477062 175477190 129 +      
ENSG00000164466 E002 0.8355110 0.0280969126 4.782325e-01 0.7442744562 5 175478560 175478563 4 + 0.272 0.150 -1.071
ENSG00000164466 E003 0.8355110 0.0280969126 4.782325e-01 0.7442744562 5 175478564 175478564 1 + 0.272 0.150 -1.071
ENSG00000164466 E004 0.8355110 0.0280969126 4.782325e-01 0.7442744562 5 175478565 175478565 1 + 0.272 0.150 -1.071
ENSG00000164466 E005 1.0717798 0.0119898016 2.800801e-01 0.5733127819 5 175478566 175478574 9 + 0.334 0.150 -1.486
ENSG00000164466 E006 2.7624704 0.0064333516 9.880806e-01 0.9998900780 5 175478575 175478589 15 + 0.539 0.542 0.012
ENSG00000164466 E007 2.7624704 0.0064333516 9.880806e-01 0.9998900780 5 175478590 175478590 1 + 0.539 0.542 0.012
ENSG00000164466 E008 2.7624704 0.0064333516 9.880806e-01 0.9998900780 5 175478591 175478591 1 + 0.539 0.542 0.012
ENSG00000164466 E009 4.9327187 0.0028479744 8.972376e-01 0.9661308138 5 175478592 175478639 48 + 0.728 0.744 0.067
ENSG00000164466 E010 0.3549719 0.0159345629 5.320218e-01   5 175478640 175478667 28 + 0.157 0.000 -12.382
ENSG00000164466 E011 0.1271363 0.0123324004 1.616537e-01   5 175491494 175491651 158 + 0.000 0.150 11.949
ENSG00000164466 E012 0.2441403 0.0163006590 4.096840e-01   5 175491652 175492094 443 + 0.059 0.150 1.514
ENSG00000164466 E013 9.0135268 0.0017035970 6.962446e-01 0.8760405418 5 175492095 175492206 112 + 0.966 0.927 -0.149
ENSG00000164466 E014 6.9490738 0.0114373962 2.290858e-01 0.5177902889 5 175492207 175492267 61 + 0.893 0.744 -0.581
ENSG00000164466 E015 0.0000000       5 175492268 175492546 279 +      
ENSG00000164466 E016 3.8225980 0.0040640039 1.618990e-01 0.4301408934 5 175509032 175509060 29 + 0.691 0.487 -0.919
ENSG00000164466 E017 10.9278382 0.0013023379 6.962687e-01 0.8760405418 5 175509061 175509202 142 + 1.041 1.004 -0.135
ENSG00000164466 E018 0.0000000       5 175509203 175509403 201 +      
ENSG00000164466 E019 7.9996277 0.0119223774 1.431997e-01 0.4029705615 5 175510109 175510207 99 + 0.952 0.776 -0.682
ENSG00000164466 E020 0.0000000       5 175510208 175510312 105 +      
ENSG00000164466 E021 0.0000000       5 175511436 175511450 15 +      
ENSG00000164466 E022 6.3408046 0.0022161756 2.237045e-01 0.5112623923 5 175511451 175511526 76 + 0.859 0.711 -0.590
ENSG00000164466 E023 0.1170040 0.0117985353 1.000000e+00   5 175511527 175511579 53 + 0.059 0.000 -10.988
ENSG00000164466 E024 6.2206186 0.0045636143 1.406842e-01 0.3989776720 5 175512111 175512196 86 + 0.859 0.674 -0.742
ENSG00000164466 E025 11.3725536 0.0259858397 1.097605e-01 0.3476932502 5 175513463 175513590 128 + 1.090 0.905 -0.685
ENSG00000164466 E026 0.4818259 0.0155568671 1.000000e+00   5 175513591 175513738 148 + 0.157 0.150 -0.071
ENSG00000164466 E027 6.4527440 0.0082200156 1.114246e-01 0.3505145905 5 175516614 175516663 50 + 0.876 0.674 -0.808
ENSG00000164466 E028 0.2438580 0.0166586506 4.091033e-01   5 175521886 175521918 33 + 0.059 0.150 1.514
ENSG00000164466 E029 5.7425453 0.0029477509 2.401542e-01 0.5294229482 5 175521919 175521968 50 + 0.823 0.674 -0.601
ENSG00000164466 E030 7.2809265 0.0019844272 3.377694e-02 0.1748975473 5 175522375 175522422 48 + 0.931 0.674 -1.016
ENSG00000164466 E031 1.9516907 0.0457920026 1.458481e-01 0.4066464804 5 175522423 175524103 1681 + 0.362 0.591 1.152
ENSG00000164466 E032 0.3795211 0.4697789597 6.097229e-02   5 175525792 175525965 174 + 0.000 0.350 12.717
ENSG00000164466 E033 125.8531946 0.0002121785 3.038336e-06 0.0001220415 5 175526638 175529742 3105 + 2.027 2.118 0.306

Help

Please Click HERE to learn more details about the results from DEXseq.