ENSG00000164548

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000297071 ENSG00000164548 No_inf pgKDN_inf TRA2A protein_coding protein_coding 53.22936 52.81824 55.26776 2.512945 1.253306 0.06538989 31.181071 25.385709 37.3144385 1.1199643 0.5574724 0.5555358 0.5874167 0.48265 0.676825 0.194175 0.01823505 0.01823505 FALSE TRUE
ENST00000482395 ENSG00000164548 No_inf pgKDN_inf TRA2A protein_coding retained_intron 53.22936 52.81824 55.26776 2.512945 1.253306 0.06538989 1.559568 3.332686 0.5185289 0.6905877 0.3103456 -2.6609538 0.0294000 0.06335 0.009225 -0.054125 0.08822073 0.01823505   TRUE
MSTRG.25928.10 ENSG00000164548 No_inf pgKDN_inf TRA2A protein_coding   53.22936 52.81824 55.26776 2.512945 1.253306 0.06538989 3.001253 1.213429 3.7034625 0.9565570 0.8132067 1.6018343 0.0552750 0.02100 0.066750 0.045750 0.31736524 0.01823505 FALSE FALSE
MSTRG.25928.11 ENSG00000164548 No_inf pgKDN_inf TRA2A protein_coding   53.22936 52.81824 55.26776 2.512945 1.253306 0.06538989 9.244259 12.663091 7.8006198 1.2117371 1.2909039 -0.6982595 0.1750667 0.24270 0.142200 -0.100500 0.41968266 0.01823505 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000164548 E001 0.1271363 0.0122891511 5.517755e-01   7 23504780 23504783 4 - 0.000 0.094 9.190
ENSG00000164548 E002 72.7460687 0.0002450916 1.177413e-01 3.624946e-01 7 23504784 23505248 465 - 1.894 1.841 -0.181
ENSG00000164548 E003 31.1567568 0.0166367023 4.004137e-01 6.838278e-01 7 23505249 23505315 67 - 1.541 1.473 -0.233
ENSG00000164548 E004 19.0644529 0.0164944796 4.620845e-01 7.326499e-01 7 23505316 23505319 4 - 1.335 1.270 -0.226
ENSG00000164548 E005 49.5350269 0.0002908697 3.050854e-01 5.983664e-01 7 23505320 23505467 148 - 1.725 1.682 -0.147
ENSG00000164548 E006 33.3878157 0.0028193528 4.055920e-01 6.883337e-01 7 23505468 23505569 102 - 1.559 1.514 -0.156
ENSG00000164548 E007 0.9646623 0.1193212828 1.811453e-01 4.570381e-01 7 23505570 23505745 176 - 0.396 0.171 -1.625
ENSG00000164548 E008 27.6878954 0.0027251923 8.538422e-01 9.484189e-01 7 23505746 23505810 65 - 1.463 1.451 -0.040
ENSG00000164548 E009 18.8745609 0.0087184496 9.896856e-01 1.000000e+00 7 23505811 23505813 3 - 1.298 1.297 -0.002
ENSG00000164548 E010 0.3730368 0.0165412832 5.991924e-01   7 23505814 23505885 72 - 0.096 0.171 0.960
ENSG00000164548 E011 22.9923555 0.0039437860 4.746743e-01 7.413512e-01 7 23506138 23506266 129 - 1.403 1.357 -0.163
ENSG00000164548 E012 2.1146185 0.0066449517 9.843272e-02 3.273241e-01 7 23506267 23506480 214 - 0.350 0.591 1.223
ENSG00000164548 E013 1.6419203 0.1127033942 5.286553e-03 5.164759e-02 7 23507157 23507419 263 - 0.096 0.591 3.545
ENSG00000164548 E014 1.4604614 0.0107279334 5.401643e-01 7.883005e-01 7 23507420 23507420 1 - 0.437 0.344 -0.525
ENSG00000164548 E015 24.4890815 0.0008714135 5.216834e-02 2.267793e-01 7 23507421 23507535 115 - 1.463 1.347 -0.401
ENSG00000164548 E016 37.0209255 0.0052654747 1.157353e-02 8.852357e-02 7 23512894 23513024 131 - 1.648 1.507 -0.480
ENSG00000164548 E017 30.8990159 0.0004726815 1.584712e-01 4.255197e-01 7 23513025 23513082 58 - 1.541 1.466 -0.257
ENSG00000164548 E018 27.0816862 0.0005240085 8.793107e-01 9.592280e-01 7 23516363 23516394 32 - 1.444 1.451 0.025
ENSG00000164548 E019 55.8384828 0.0007576145 3.140093e-01 6.071173e-01 7 23516395 23516528 134 - 1.733 1.772 0.132
ENSG00000164548 E020 52.6688168 0.0003451896 1.599652e-01 4.275271e-01 7 23521707 23521840 134 - 1.758 1.701 -0.194
ENSG00000164548 E021 31.0583804 0.0005282027 1.445405e-10 1.419972e-08 7 23521841 23522120 280 - 1.287 1.638 1.210
ENSG00000164548 E022 8.3711826 0.0017264505 6.239259e-06 2.273704e-04 7 23522121 23522131 11 - 0.674 1.132 1.754
ENSG00000164548 E023 28.6499274 0.0006156798 7.934339e-08 4.728515e-06 7 23522132 23522353 222 - 1.287 1.590 1.045
ENSG00000164548 E024 12.0021066 0.0047384162 6.427775e-03 5.934194e-02 7 23522354 23522432 79 - 0.975 1.210 0.850
ENSG00000164548 E025 1.7427112 0.0083298027 1.177572e-01 3.624946e-01 7 23531181 23531270 90 - 0.299 0.533 1.282
ENSG00000164548 E026 3.5139958 0.1306975453 9.785403e-03 7.919657e-02 7 23531417 23531788 372 - 0.351 0.817 2.162
ENSG00000164548 E027 31.5879531 0.0027417271 4.703893e-04 8.326633e-03 7 23531789 23532041 253 - 1.604 1.409 -0.671

Help

Please Click HERE to learn more details about the results from DEXseq.