ENSG00000164654

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000340080 ENSG00000164654 No_inf pgKDN_inf MIOS protein_coding protein_coding 19.58691 13.85818 24.70514 0.3123091 0.8691206 0.8336162 3.1525109 1.4489659 7.366178 0.6854193 1.8283370 2.3379273 0.14472500 0.106000 0.295375 0.189375 0.41734007 0.03114304 FALSE TRUE
ENST00000405785 ENSG00000164654 No_inf pgKDN_inf MIOS protein_coding protein_coding 19.58691 13.85818 24.70514 0.3123091 0.8691206 0.8336162 5.8309680 4.4416949 3.900815 0.5314536 2.5696709 -0.1868853 0.31941667 0.321500 0.164150 -0.157350 0.49012426 0.03114304 FALSE TRUE
ENST00000433635 ENSG00000164654 No_inf pgKDN_inf MIOS protein_coding protein_coding 19.58691 13.85818 24.70514 0.3123091 0.8691206 0.8336162 1.2206225 0.0000000 2.784973 0.0000000 1.8703310 8.1266904 0.04744167 0.000000 0.106150 0.106150 0.57016131 0.03114304 FALSE TRUE
ENST00000445169 ENSG00000164654 No_inf pgKDN_inf MIOS protein_coding protein_coding 19.58691 13.85818 24.70514 0.3123091 0.8691206 0.8336162 2.7529996 1.4393481 3.645010 0.3826267 0.7260559 1.3344713 0.13633333 0.102225 0.149500 0.047275 0.83804119 0.03114304 FALSE TRUE
ENST00000493227 ENSG00000164654 No_inf pgKDN_inf MIOS protein_coding retained_intron 19.58691 13.85818 24.70514 0.3123091 0.8691206 0.8336162 1.6434402 2.8550020 1.000923 0.5675099 0.2036072 -1.5028635 0.09705833 0.203750 0.040250 -0.163500 0.03114304 0.03114304 FALSE TRUE
MSTRG.25832.3 ENSG00000164654 No_inf pgKDN_inf MIOS protein_coding   19.58691 13.85818 24.70514 0.3123091 0.8691206 0.8336162 1.8030040 1.2853103 2.898429 0.7614413 1.1047951 1.1669424 0.08682500 0.092300 0.114075 0.021775 0.85626796 0.03114304 FALSE TRUE
MSTRG.25832.6 ENSG00000164654 No_inf pgKDN_inf MIOS protein_coding   19.58691 13.85818 24.70514 0.3123091 0.8691206 0.8336162 1.5228538 0.4946537 1.964225 0.2855902 1.4888957 1.9679211 0.07670000 0.036225 0.083575 0.047350 1.00000000 0.03114304 FALSE TRUE
MSTRG.25832.8 ENSG00000164654 No_inf pgKDN_inf MIOS protein_coding   19.58691 13.85818 24.70514 0.3123091 0.8691206 0.8336162 0.3518347 0.9477202 0.000000 0.9477202 0.0000000 -6.5815323 0.02503333 0.070650 0.000000 -0.070650 0.82432129 0.03114304 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000164654 E001 0.0000000       7 7566875 7566883 9 +      
ENSG00000164654 E002 0.0000000       7 7566884 7566893 10 +      
ENSG00000164654 E003 0.0000000       7 7566894 7566960 67 +      
ENSG00000164654 E004 0.0000000       7 7566961 7566987 27 +      
ENSG00000164654 E005 1.5482913 0.0205153855 5.542300e-02 0.2345930091 7 7566988 7567052 65 + 0.507 0.203 -1.891
ENSG00000164654 E006 2.4091054 0.0083905837 3.377852e-01 0.6295783577 7 7567053 7567072 20 + 0.581 0.445 -0.654
ENSG00000164654 E007 2.8977220 0.0712241404 3.143346e-01 0.6074065341 7 7567073 7567294 222 + 0.645 0.490 -0.712
ENSG00000164654 E008 6.1810223 0.0022882516 4.473524e-01 0.7215080453 7 7567295 7567482 188 + 0.883 0.804 -0.306
ENSG00000164654 E009 1.9241968 0.0292474231 2.179081e-01 0.5042907849 7 7567483 7567484 2 + 0.533 0.341 -1.016
ENSG00000164654 E010 1.9405649 0.0099211437 8.111998e-01 0.9305245249 7 7567485 7567606 122 + 0.479 0.445 -0.168
ENSG00000164654 E011 4.0950706 0.0035494287 8.919224e-02 0.3100178277 7 7567607 7567688 82 + 0.780 0.566 -0.905
ENSG00000164654 E012 9.1740753 0.0016077880 6.502974e-02 0.2568707877 7 7568026 7568123 98 + 1.066 0.895 -0.636
ENSG00000164654 E013 116.4540705 0.0002926251 1.298082e-05 0.0004268949 7 7572436 7573769 1334 + 2.107 1.999 -0.362
ENSG00000164654 E014 16.5794276 0.0009364658 3.951742e-01 0.6799376588 7 7574098 7574196 99 + 1.212 1.276 0.228
ENSG00000164654 E015 0.4914576 0.0159214178 7.036685e-01   7 7581729 7581844 116 + 0.147 0.203 0.569
ENSG00000164654 E016 2.2145975 0.0068489667 2.042235e-01 0.4870264208 7 7582630 7582819 190 + 0.416 0.600 0.891
ENSG00000164654 E017 1.6133083 0.0205047889 4.340545e-02 0.2032320092 7 7582954 7583117 164 + 0.256 0.566 1.739
ENSG00000164654 E018 48.7627514 0.0003314098 2.092910e-01 0.4935302055 7 7583118 7583372 255 + 1.667 1.723 0.191
ENSG00000164654 E019 37.9773993 0.0004298645 6.732341e-01 0.8646728614 7 7585636 7585805 170 + 1.575 1.599 0.083
ENSG00000164654 E020 21.4349492 0.0006992665 5.687072e-01 0.8060140322 7 7588498 7588563 66 + 1.328 1.368 0.139
ENSG00000164654 E021 10.3302060 0.0016637882 9.249685e-01 0.9772559022 7 7589405 7589412 8 + 1.051 1.047 -0.016
ENSG00000164654 E022 32.7182091 0.0031286942 8.977019e-01 0.9662565923 7 7589413 7589563 151 + 1.518 1.529 0.037
ENSG00000164654 E023 32.0297397 0.0004276630 4.865704e-01 0.7501339407 7 7594980 7595132 153 + 1.496 1.536 0.138
ENSG00000164654 E024 40.2356844 0.0032391904 7.513601e-01 0.9020092383 7 7596257 7596461 205 + 1.615 1.603 -0.042
ENSG00000164654 E025 1.6048117 0.0438439194 1.550629e-01 0.4207351386 7 7605118 7605941 824 + 0.302 0.530 1.247
ENSG00000164654 E026 30.0693242 0.0103660854 5.028644e-01 0.7624860550 7 7605942 7606071 130 + 1.467 1.513 0.157
ENSG00000164654 E027 62.2872031 0.0050026935 1.013592e-03 0.0151625419 7 7606996 7608952 1957 + 1.726 1.876 0.506

Help

Please Click HERE to learn more details about the results from DEXseq.