ENSG00000164877

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000297508 ENSG00000164877 No_inf pgKDN_inf MICALL2 protein_coding protein_coding 9.184041 11.23766 5.793965 1.179573 0.5032472 -0.954514 2.6835835 1.5760332 2.6801766 0.59714814 0.33745485 0.7622779 0.32415833 0.150175 0.464425 0.314250 2.518355e-01 1.151864e-05 FALSE TRUE
ENST00000467783 ENSG00000164877 No_inf pgKDN_inf MICALL2 protein_coding retained_intron 9.184041 11.23766 5.793965 1.179573 0.5032472 -0.954514 1.7573151 3.8890527 0.0000000 0.75114414 0.00000000 -8.6069798 0.14422500 0.341475 0.000000 -0.341475 1.151864e-05 1.151864e-05 FALSE FALSE
ENST00000472100 ENSG00000164877 No_inf pgKDN_inf MICALL2 protein_coding retained_intron 9.184041 11.23766 5.793965 1.179573 0.5032472 -0.954514 0.8488188 1.2958643 0.4942056 0.05331657 0.24596644 -1.3729209 0.10025000 0.117750 0.097850 -0.019900 8.471274e-01 1.151864e-05 TRUE TRUE
ENST00000487156 ENSG00000164877 No_inf pgKDN_inf MICALL2 protein_coding retained_intron 9.184041 11.23766 5.793965 1.179573 0.5032472 -0.954514 0.5589800 0.3485826 0.7159040 0.19283543 0.31104223 1.0174732 0.06802500 0.034475 0.112000 0.077525 6.407467e-01 1.151864e-05 FALSE FALSE
ENST00000493998 ENSG00000164877 No_inf pgKDN_inf MICALL2 protein_coding retained_intron 9.184041 11.23766 5.793965 1.179573 0.5032472 -0.954514 0.2524844 0.7574533 0.0000000 0.46296025 0.00000000 -6.2620071 0.01944167 0.058325 0.000000 -0.058325 6.476525e-01 1.151864e-05   FALSE
ENST00000496184 ENSG00000164877 No_inf pgKDN_inf MICALL2 protein_coding retained_intron 9.184041 11.23766 5.793965 1.179573 0.5032472 -0.954514 0.6142325 0.5748410 0.1179228 0.21224439 0.09155809 -2.1927709 0.06575833 0.055175 0.019150 -0.036025 8.240394e-01 1.151864e-05 TRUE FALSE
MSTRG.25732.16 ENSG00000164877 No_inf pgKDN_inf MICALL2 protein_coding   9.184041 11.23766 5.793965 1.179573 0.5032472 -0.954514 0.6262161 1.1513222 0.3523649 0.45681743 0.22253352 -1.6802532 0.06277500 0.100300 0.063300 -0.037000 8.612865e-01 1.151864e-05 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000164877 E001 0.1271363 0.012339947 7.997545e-01   7 1428465 1428478 14 - 0.000 0.080 9.130
ENSG00000164877 E002 0.2447669 0.016109289 7.656571e-01   7 1428479 1428618 140 - 0.113 0.080 -0.548
ENSG00000164877 E003 0.7526526 0.013470605 2.148517e-01 0.5004236647 7 1428619 1428791 173 - 0.113 0.304 1.774
ENSG00000164877 E004 0.0000000       7 1434210 1434358 149 -      
ENSG00000164877 E005 0.0000000       7 1434359 1434359 1 -      
ENSG00000164877 E006 0.1176306 0.011666283 3.616076e-01   7 1434360 1434360 1 - 0.113 0.000 -13.354
ENSG00000164877 E007 0.2447669 0.016109289 7.656571e-01   7 1434361 1434365 5 - 0.113 0.080 -0.548
ENSG00000164877 E008 0.3716209 0.016531975 8.540560e-01   7 1434366 1434398 33 - 0.113 0.148 0.452
ENSG00000164877 E009 1.2138009 0.012403201 2.205504e-01 0.5075162212 7 1434399 1434452 54 - 0.443 0.258 -1.133
ENSG00000164877 E010 6.9076121 0.083402269 9.411940e-01 0.9834117333 7 1434453 1434672 220 - 0.876 0.897 0.080
ENSG00000164877 E011 6.4116075 0.003333377 2.612835e-05 0.0007730149 7 1434673 1434899 227 - 0.487 0.996 2.104
ENSG00000164877 E012 2.0868543 0.052027589 6.251537e-01 0.8386280247 7 1434900 1435100 201 - 0.527 0.450 -0.379
ENSG00000164877 E013 2.3312458 0.204906806 6.007299e-01 0.8252194768 7 1435101 1435147 47 - 0.564 0.480 -0.398
ENSG00000164877 E014 1.9671114 0.008082945 7.991651e-01 0.9246614508 7 1436742 1436742 1 - 0.487 0.450 -0.186
ENSG00000164877 E015 5.0757850 0.003149245 3.968841e-01 0.6813382972 7 1436743 1436856 114 - 0.711 0.811 0.399
ENSG00000164877 E016 5.2816996 0.002888023 1.908518e-04 0.0040287280 7 1436857 1437433 577 - 0.443 0.918 2.037
ENSG00000164877 E017 1.8810513 0.017005421 9.797499e-02 0.3263855997 7 1437434 1437534 101 - 0.276 0.535 1.452
ENSG00000164877 E018 2.1048280 0.026449283 6.759802e-01 0.8658253105 7 1437535 1437535 1 - 0.443 0.509 0.326
ENSG00000164877 E019 4.4526053 0.003684090 5.853695e-01 0.8158174125 7 1437536 1437608 73 - 0.686 0.752 0.275
ENSG00000164877 E020 0.0000000       7 1437609 1437611 3 -      
ENSG00000164877 E021 4.5359346 0.003579116 3.188129e-01 0.6114229525 7 1437890 1437980 91 - 0.801 0.685 -0.470
ENSG00000164877 E022 0.4981306 0.016960754 5.399245e-01   7 1437981 1438096 116 - 0.113 0.206 1.037
ENSG00000164877 E023 5.2535913 0.002788930 8.510380e-02 0.3016553982 7 1438097 1438220 124 - 0.893 0.703 -0.750
ENSG00000164877 E024 0.8508417 0.199784327 4.513687e-01 0.7244895432 7 1438221 1438288 68 - 0.339 0.206 -0.962
ENSG00000164877 E025 2.6857496 0.077678069 2.606949e-01 0.5532290641 7 1438289 1438353 65 - 0.658 0.481 -0.812
ENSG00000164877 E026 1.3625013 0.124256891 7.901365e-01 0.9195307573 7 1438354 1438839 486 - 0.339 0.383 0.258
ENSG00000164877 E027 3.9156620 0.033315358 3.608235e-01 0.6503793897 7 1438840 1438924 85 - 0.759 0.627 -0.548
ENSG00000164877 E028 3.2005861 0.011243070 8.715520e-01 0.9558954892 7 1438925 1438991 67 - 0.629 0.606 -0.101
ENSG00000164877 E029 0.6189413 0.123817908 9.921586e-01 1.0000000000 7 1438992 1438995 4 - 0.202 0.206 0.036
ENSG00000164877 E030 2.5145949 0.141745776 6.403892e-02 0.2549173254 7 1438996 1439871 876 - 0.276 0.648 1.955
ENSG00000164877 E031 5.3160989 0.003088846 6.547132e-01 0.8551194230 7 1439925 1440085 161 - 0.759 0.811 0.207
ENSG00000164877 E032 1.9353900 0.059223782 4.309695e-02 0.2024031709 7 1440086 1440590 505 - 0.629 0.304 -1.686
ENSG00000164877 E033 5.2153027 0.003199408 1.967178e-01 0.4776167150 7 1440591 1440684 94 - 0.686 0.837 0.609
ENSG00000164877 E034 13.2560068 0.001128320 1.909014e-01 0.4702479245 7 1440685 1442191 1507 - 1.077 1.181 0.372
ENSG00000164877 E035 3.3546375 0.004609494 2.399921e-01 0.5292002301 7 1442192 1442215 24 - 0.527 0.685 0.700
ENSG00000164877 E036 8.5712182 0.004771164 1.120110e-01 0.3516621058 7 1442216 1442484 269 - 1.055 0.908 -0.548
ENSG00000164877 E037 3.6601069 0.004495532 1.596099e-01 0.4270482589 7 1444652 1444729 78 - 0.759 0.584 -0.741
ENSG00000164877 E038 4.0532619 0.005253803 5.678391e-01 0.8055190317 7 1444730 1444874 145 - 0.736 0.667 -0.285
ENSG00000164877 E039 5.0366366 0.002827762 4.492226e-01 0.7230131750 7 1444875 1445070 196 - 0.821 0.737 -0.337
ENSG00000164877 E040 1.9790716 0.007549706 8.039245e-01 0.9271629631 7 1445071 1445124 54 - 0.443 0.481 0.189
ENSG00000164877 E041 6.7369168 0.003572944 2.015850e-01 0.4840086862 7 1445125 1445428 304 - 0.954 0.824 -0.496
ENSG00000164877 E042 0.0000000       7 1446657 1446712 56 -      
ENSG00000164877 E043 3.9536905 0.004695276 7.276680e-01 0.8913192823 7 1446713 1446828 116 - 0.658 0.703 0.189
ENSG00000164877 E044 5.5038991 0.004003176 1.544560e-01 0.4198759087 7 1447575 1447765 191 - 0.893 0.737 -0.612
ENSG00000164877 E045 0.2459004 0.016398185 7.649433e-01   7 1447766 1448033 268 - 0.113 0.080 -0.548
ENSG00000164877 E046 3.9044978 0.004533143 7.367358e-02 0.2762835909 7 1448620 1448761 142 - 0.801 0.584 -0.911
ENSG00000164877 E047 1.6072396 0.019692193 8.837105e-01 0.9609282696 7 1450240 1450288 49 - 0.394 0.418 0.130
ENSG00000164877 E048 0.4804091 0.015898128 1.683969e-01   7 1450289 1450536 248 - 0.276 0.080 -2.133
ENSG00000164877 E049 3.5667031 0.004940133 6.407639e-01 0.8475765162 7 1459184 1459478 295 - 0.686 0.627 -0.249

Help

Please Click HERE to learn more details about the results from DEXseq.