ENSG00000165006

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000297661 ENSG00000165006 No_inf pgKDN_inf UBAP1 protein_coding protein_coding 22.02741 18.10948 26.11596 0.3620355 0.8798904 0.5279424 15.2769554 7.030732 22.7177126 2.241827 2.3482387 1.6906552 0.66159167 0.388825 0.867075 0.478250 0.03467381 0.03467381 FALSE TRUE
ENST00000359544 ENSG00000165006 No_inf pgKDN_inf UBAP1 protein_coding protein_coding 22.02741 18.10948 26.11596 0.3620355 0.8798904 0.5279424 0.7173838 2.152151 0.0000000 1.303962 0.0000000 -7.7563238 0.03986667 0.119600 0.000000 -0.119600 0.43789562 0.03467381 FALSE TRUE
ENST00000625521 ENSG00000165006 No_inf pgKDN_inf UBAP1 protein_coding protein_coding 22.02741 18.10948 26.11596 0.3620355 0.8798904 0.5279424 2.5805326 2.321717 2.6965444 1.414997 1.2963954 0.2150591 0.12101667 0.131375 0.104300 -0.027075 0.94940129 0.03467381 FALSE TRUE
ENST00000626262 ENSG00000165006 No_inf pgKDN_inf UBAP1 protein_coding protein_coding 22.02741 18.10948 26.11596 0.3620355 0.8798904 0.5279424 2.7217059 4.412376 0.7017073 2.770997 0.7017073 -2.6354657 0.13717500 0.239150 0.028625 -0.210525 0.74706960 0.03467381 FALSE TRUE
MSTRG.28624.5 ENSG00000165006 No_inf pgKDN_inf UBAP1 protein_coding   22.02741 18.10948 26.11596 0.3620355 0.8798904 0.5279424 0.7308359 2.192508 0.0000000 2.192508 0.0000000 -7.7830032 0.04035000 0.121050 0.000000 -0.121050 0.83609009 0.03467381 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000165006 E001 0.3628435 0.0165715672 0.75976824   9 34179005 34179037 33 + 0.155 0.107 -0.615
ENSG00000165006 E002 0.3628435 0.0165715672 0.75976824   9 34179038 34179042 5 + 0.155 0.107 -0.615
ENSG00000165006 E003 0.3628435 0.0165715672 0.75976824   9 34179043 34179044 2 + 0.155 0.107 -0.615
ENSG00000165006 E004 12.9268688 0.0012246009 0.01279783 0.0942948 9 34179045 34179240 196 + 1.221 1.022 -0.717
ENSG00000165006 E005 0.2539903 0.0160537766 0.16479620   9 34220372 34220438 67 + 0.000 0.193 10.684
ENSG00000165006 E006 0.3808443 0.0251329424 0.06271949   9 34220439 34220467 29 + 0.000 0.265 11.182
ENSG00000165006 E007 9.4268910 0.0019908250 0.03967663 0.1930578 9 34220908 34220948 41 + 1.092 0.903 -0.699
ENSG00000165006 E008 12.8038212 0.0087955375 0.01611746 0.1102115 9 34234216 34234340 125 + 1.221 1.010 -0.760
ENSG00000165006 E009 119.2823584 0.0001638901 0.72211433 0.8882975 9 34241185 34242108 924 + 2.081 2.075 -0.021
ENSG00000165006 E010 31.9707831 0.0005177985 0.68262594 0.8685848 9 34249779 34249961 183 + 1.506 1.528 0.075
ENSG00000165006 E011 20.1498724 0.0094513579 0.37199948 0.6598724 9 34250658 34250759 102 + 1.293 1.358 0.228
ENSG00000165006 E012 103.3500993 0.0002261181 0.02214666 0.1352420 9 34251392 34252523 1132 + 1.989 2.047 0.194

Help

Please Click HERE to learn more details about the results from DEXseq.