ENSG00000165233

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000375464 ENSG00000165233 No_inf pgKDN_inf CARD19 protein_coding protein_coding 197.2987 106.5041 256.0747 7.112683 12.22157 1.265576 125.961193 58.87113 164.452676 2.9533433 1.511527 1.4818829 0.62715833 0.561525 0.646000 0.084475 0.573723942 0.001856367 FALSE  
ENST00000466409 ENSG00000165233 No_inf pgKDN_inf CARD19 protein_coding nonsense_mediated_decay 197.2987 106.5041 256.0747 7.112683 12.22157 1.265576 7.648257 8.22521 6.803587 0.6293885 0.371452 -0.2733908 0.04625833 0.077400 0.026725 -0.050675 0.008921158 0.001856367 TRUE  
ENST00000475574 ENSG00000165233 No_inf pgKDN_inf CARD19 protein_coding protein_coding_CDS_not_defined 197.2987 106.5041 256.0747 7.112683 12.22157 1.265576 15.854049 12.29040 25.094173 7.3055823 15.653021 1.0292219 0.07812500 0.104025 0.090100 -0.013925 1.000000000 0.001856367 FALSE  
MSTRG.28979.1 ENSG00000165233 No_inf pgKDN_inf CARD19 protein_coding   197.2987 106.5041 256.0747 7.112683 12.22157 1.265576 29.155652 13.33354 39.007943 1.4441628 6.920188 1.5479964 0.14533333 0.125675 0.155725 0.030050 0.855000869 0.001856367 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000165233 E001 1.199328 0.0270174242 3.418428e-01 6.333109e-01 9 93096212 93096216 5 + 0.380 0.227 -1.031
ENSG00000165233 E002 1.325835 0.0516498211 6.531524e-01 8.541772e-01 9 93096217 93096217 1 + 0.380 0.307 -0.448
ENSG00000165233 E003 1.444538 0.0444720328 5.240013e-01 7.771540e-01 9 93096218 93096222 5 + 0.411 0.307 -0.618
ENSG00000165233 E004 5.419935 0.0151625479 3.212229e-01 6.142758e-01 9 93096223 93096227 5 + 0.831 0.708 -0.492
ENSG00000165233 E005 22.769937 0.0010052988 8.696690e-01 9.551341e-01 9 93096228 93096256 29 + 1.353 1.366 0.047
ENSG00000165233 E006 39.408450 0.0013870841 4.358744e-01 7.123341e-01 9 93096257 93096277 21 + 1.601 1.563 -0.127
ENSG00000165233 E007 65.194835 0.0002294846 1.995002e-03 2.552751e-02 9 93096278 93096314 37 + 1.841 1.722 -0.402
ENSG00000165233 E008 54.728555 0.0002584829 1.315173e-02 9.606251e-02 9 93096315 93096322 8 + 1.761 1.658 -0.350
ENSG00000165233 E009 68.693265 0.0002192213 3.631596e-03 3.975370e-02 9 93096323 93096352 30 + 1.860 1.752 -0.365
ENSG00000165233 E010 84.397847 0.0002341248 4.930175e-03 4.909602e-02 9 93107674 93107747 74 + 1.944 1.850 -0.314
ENSG00000165233 E011 87.984804 0.0002158016 2.745828e-01 5.681520e-01 9 93107748 93107816 69 + 1.942 1.909 -0.111
ENSG00000165233 E012 25.658085 0.0005453587 9.895750e-01 1.000000e+00 9 93107817 93107827 11 + 1.407 1.409 0.008
ENSG00000165233 E013 3.993812 0.0111271974 5.185954e-06 1.939662e-04 9 93108991 93109092 102 + 0.380 0.964 2.552
ENSG00000165233 E014 19.602610 0.0006951868 8.009643e-18 1.785091e-15 9 93109093 93109891 799 + 0.997 1.575 2.036
ENSG00000165233 E015 13.639782 0.0010763280 6.931356e-12 8.056805e-10 9 93109892 93110567 676 + 0.874 1.415 1.948
ENSG00000165233 E016 107.969679 0.0001496369 3.149950e-01 6.078550e-01 9 93110568 93110634 67 + 2.028 2.001 -0.089
ENSG00000165233 E017 117.235693 0.0001706243 1.607390e-01 4.287087e-01 9 93110635 93110721 87 + 2.066 2.030 -0.123
ENSG00000165233 E018 40.318851 0.0004491054 2.226164e-20 6.221032e-18 9 93110722 93111878 1157 + 1.388 1.826 1.494
ENSG00000165233 E019 87.078843 0.0001806735 5.988136e-01 8.240431e-01 9 93111879 93111938 60 + 1.919 1.939 0.069
ENSG00000165233 E020 25.101549 0.0029126506 2.664770e-10 2.512617e-08 9 93111939 93112217 279 + 1.215 1.610 1.366
ENSG00000165233 E021 104.655341 0.0001592026 2.193004e-01 5.059770e-01 9 93112218 93112289 72 + 2.017 1.983 -0.113
ENSG00000165233 E022 142.710349 0.0001315353 1.342740e-02 9.733783e-02 9 93112992 93113283 292 + 2.159 2.099 -0.201

Help

Please Click HERE to learn more details about the results from DEXseq.