ENSG00000166037

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000325542 ENSG00000166037 No_inf pgKDN_inf CEP57 protein_coding protein_coding 15.23148 14.26525 16.21014 1.509805 0.5463318 0.1842699 10.4072451 8.0990985 11.7110372 0.29396645 1.60125812 0.5314868 0.68498333 0.585500 0.716900 0.131400 0.66282663 0.01944119 FALSE TRUE
ENST00000538158 ENSG00000166037 No_inf pgKDN_inf CEP57 protein_coding retained_intron 15.23148 14.26525 16.21014 1.509805 0.5463318 0.1842699 0.8274183 1.0414302 0.7489727 0.06518635 0.04060077 -0.4702332 0.05585833 0.075475 0.046350 -0.029125 0.82404223 0.01944119 FALSE TRUE
ENST00000541150 ENSG00000166037 No_inf pgKDN_inf CEP57 protein_coding protein_coding 15.23148 14.26525 16.21014 1.509805 0.5463318 0.1842699 0.4035110 0.0000000 1.2105329 0.00000000 1.21053288 6.9313674 0.02682500 0.000000 0.080475 0.080475 0.85564451 0.01944119 FALSE TRUE
ENST00000541768 ENSG00000166037 No_inf pgKDN_inf CEP57 protein_coding retained_intron 15.23148 14.26525 16.21014 1.509805 0.5463318 0.1842699 0.3167072 0.9501215 0.0000000 0.95012148 0.00000000 -6.5851451 0.01715000 0.051450 0.000000 -0.051450 0.83631271 0.01944119 FALSE FALSE
MSTRG.5431.16 ENSG00000166037 No_inf pgKDN_inf CEP57 protein_coding   15.23148 14.26525 16.21014 1.509805 0.5463318 0.1842699 1.4349582 2.9485017 0.0000000 0.99278864 0.00000000 -8.2087229 0.09671667 0.200325 0.000000 -0.200325 0.01944119 0.01944119 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000166037 E001 0.0000000       11 95789965 95790142 178 +      
ENSG00000166037 E002 0.1265070 0.012257666 0.481480244   11 95790461 95790497 37 + 0.000 0.101 9.261
ENSG00000166037 E003 0.3720642 0.016639414 0.517261812   11 95790498 95790512 15 + 0.090 0.183 1.189
ENSG00000166037 E004 0.6172093 0.016031521 0.570543822 0.80700600 11 95790513 95790515 3 + 0.164 0.251 0.774
ENSG00000166037 E005 0.7342133 0.014037657 0.892178200 0.96417478 11 95790516 95790521 6 + 0.227 0.251 0.189
ENSG00000166037 E006 0.9705471 0.012318710 0.582361939 0.81391263 11 95790522 95790530 9 + 0.332 0.251 -0.548
ENSG00000166037 E007 0.9705471 0.012318710 0.582361939 0.81391263 11 95790531 95790532 2 + 0.332 0.251 -0.548
ENSG00000166037 E008 5.0309445 0.008608639 0.426452478 0.70504341 11 95790533 95790658 126 + 0.729 0.829 0.401
ENSG00000166037 E009 6.6032059 0.002214353 0.886876230 0.96213985 11 95790659 95790743 85 + 0.870 0.892 0.082
ENSG00000166037 E010 0.0000000       11 95794221 95794359 139 +      
ENSG00000166037 E011 0.0000000       11 95795516 95795541 26 +      
ENSG00000166037 E012 0.0000000       11 95795542 95795559 18 +      
ENSG00000166037 E013 4.5179211 0.007126325 0.883876091 0.96094644 11 95799232 95799236 5 + 0.747 0.736 -0.045
ENSG00000166037 E014 12.6082755 0.001289361 0.044150296 0.20545316 11 95799237 95799388 152 + 1.201 1.049 -0.548
ENSG00000166037 E015 0.0000000       11 95812904 95812929 26 +      
ENSG00000166037 E016 0.0000000       11 95812930 95812931 2 +      
ENSG00000166037 E017 4.4389656 0.017071664 0.007303195 0.06495847 11 95812932 95812951 20 + 0.870 0.525 -1.448
ENSG00000166037 E018 4.5664151 0.011798024 0.011824989 0.08972133 11 95812952 95812976 25 + 0.870 0.558 -1.296
ENSG00000166037 E019 14.1997186 0.001025351 0.053738465 0.23070297 11 95812977 95813111 135 + 1.243 1.106 -0.489
ENSG00000166037 E020 13.6590078 0.001238432 0.588493430 0.81742524 11 95813468 95813589 122 + 1.182 1.148 -0.121
ENSG00000166037 E021 0.0000000       11 95815118 95815260 143 +      
ENSG00000166037 E022 8.4241240 0.022314386 0.910585469 0.97167002 11 95817787 95817819 33 + 0.977 0.971 -0.020
ENSG00000166037 E023 7.3314159 0.042653154 0.895982501 0.96578087 11 95817820 95817836 17 + 0.909 0.933 0.093
ENSG00000166037 E024 8.4442399 0.001705465 0.726469844 0.89052740 11 95817837 95817903 67 + 0.955 0.995 0.147
ENSG00000166037 E025 0.1272623 0.012386224 0.481267385   11 95817904 95818032 129 + 0.000 0.101 11.395
ENSG00000166037 E026 3.0608998 0.013395673 0.942667895 0.98412031 11 95818827 95818904 78 + 0.600 0.617 0.074
ENSG00000166037 E027 0.0000000       11 95821871 95821978 108 +      
ENSG00000166037 E028 0.0000000       11 95821979 95822498 520 +      
ENSG00000166037 E029 0.0000000       11 95822499 95822576 78 +      
ENSG00000166037 E030 0.0000000       11 95822577 95823215 639 +      
ENSG00000166037 E031 1.1347253 0.125753703 0.019007628 0.12279552 11 95824117 95824230 114 + 0.090 0.490 3.189
ENSG00000166037 E032 10.0036432 0.001371510 0.008044523 0.06937533 11 95825683 95827785 2103 + 0.909 1.148 0.879
ENSG00000166037 E033 18.0233336 0.007716329 0.295434805 0.58869829 11 95827786 95828027 242 + 1.237 1.319 0.287
ENSG00000166037 E034 11.9945679 0.001245646 0.718602843 0.88671520 11 95829187 95829331 145 + 1.096 1.132 0.130
ENSG00000166037 E035 93.0904136 0.011281208 0.558265039 0.79995395 11 95831026 95832693 1668 + 1.958 1.989 0.102

Help

Please Click HERE to learn more details about the results from DEXseq.