ENSG00000166123

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000340124 ENSG00000166123 No_inf pgKDN_inf GPT2 protein_coding protein_coding 4.639056 4.650529 5.680102 0.1990936 0.7119513 0.2879609 3.1123292 2.8237983 3.19062005 0.6465437 0.40059531 0.1756143 0.71370000 0.609750 0.599400 -0.010350 0.99947710 0.02808419 FALSE TRUE
ENST00000562132 ENSG00000166123 No_inf pgKDN_inf GPT2 protein_coding protein_coding 4.639056 4.650529 5.680102 0.1990936 0.7119513 0.2879609 0.7164746 0.0000000 2.14942365 0.0000000 0.73051742 7.7545025 0.11440000 0.000000 0.343200 0.343200 0.02808419 0.02808419 FALSE FALSE
ENST00000562801 ENSG00000166123 No_inf pgKDN_inf GPT2 protein_coding retained_intron 4.639056 4.650529 5.680102 0.1990936 0.7119513 0.2879609 0.4714338 1.0060561 0.26291057 0.3085095 0.11448269 -1.8964799 0.10082500 0.219300 0.045725 -0.173575 0.47627308 0.02808419 FALSE TRUE
ENST00000569193 ENSG00000166123 No_inf pgKDN_inf GPT2 protein_coding retained_intron 4.639056 4.650529 5.680102 0.1990936 0.7119513 0.2879609 0.1781299 0.3864014 0.02935674 0.2230897 0.02935674 -3.3322795 0.03940833 0.082475 0.005150 -0.077325 0.62579827 0.02808419 FALSE TRUE
MSTRG.11114.2 ENSG00000166123 No_inf pgKDN_inf GPT2 protein_coding   4.639056 4.650529 5.680102 0.1990936 0.7119513 0.2879609 0.1447577 0.4342731 0.00000000 0.2776266 0.00000000 -5.4733750 0.02950000 0.088500 0.000000 -0.088500 0.48564359 0.02808419 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000166123 E001 1.2079181 0.0107843397 0.1259130283 0.376235364 16 46884362 46884467 106 + 0.456 0.225 -1.451
ENSG00000166123 E002 1.0811292 0.0114425441 0.0521683980 0.226779268 16 46884694 46884694 1 + 0.456 0.162 -2.036
ENSG00000166123 E003 1.4443169 0.0131360143 0.0426605903 0.201282399 16 46884695 46884724 30 + 0.529 0.225 -1.813
ENSG00000166123 E004 2.6759940 0.0060856609 0.2162337623 0.502362771 16 46884725 46884834 110 + 0.648 0.482 -0.759
ENSG00000166123 E005 2.6584649 0.0055102003 0.0353318982 0.179933339 16 46884835 46884958 124 + 0.697 0.412 -1.328
ENSG00000166123 E006 0.0000000       16 46884959 46885331 373 +      
ENSG00000166123 E007 0.1187032 0.0118266260 0.4557204376   16 46885467 46885577 111 + 0.102 0.000 -8.487
ENSG00000166123 E008 3.6888070 0.0300947565 0.9050878803 0.969552112 16 46897648 46897737 90 + 0.673 0.665 -0.036
ENSG00000166123 E009 3.5524407 0.1873799386 0.6374078242 0.845272689 16 46900682 46900790 109 + 0.697 0.620 -0.328
ENSG00000166123 E010 4.1146119 0.0037913809 0.0101198688 0.080871981 16 46906842 46906975 134 + 0.851 0.543 -1.292
ENSG00000166123 E011 5.9969657 0.0025864809 0.4658649805 0.734773728 16 46909684 46909893 210 + 0.882 0.808 -0.287
ENSG00000166123 E012 2.0755614 0.0459915247 0.5712593475 0.807482484 16 46909894 46909927 34 + 0.529 0.449 -0.397
ENSG00000166123 E013 3.2420031 0.1991081567 0.1094691652 0.347273207 16 46915298 46916627 1330 + 0.413 0.742 1.509
ENSG00000166123 E014 3.6821706 0.0043274808 0.9358139197 0.981605429 16 46916628 46916707 80 + 0.673 0.665 -0.036
ENSG00000166123 E015 3.8251392 0.0041629505 0.4141057321 0.694454005 16 46918621 46918757 137 + 0.621 0.724 0.435
ENSG00000166123 E016 4.0825159 0.0418161623 0.3495268972 0.639931854 16 46922242 46922416 175 + 0.621 0.760 0.579
ENSG00000166123 E017 0.7520536 0.2153717178 0.2049092485 0.488079115 16 46923833 46924388 556 + 0.102 0.329 2.094
ENSG00000166123 E018 5.6277037 0.0028022822 0.3890248148 0.674912003 16 46924389 46924544 156 + 0.867 0.776 -0.354
ENSG00000166123 E019 4.0104333 0.0048634439 0.0902524846 0.312008383 16 46926925 46927037 113 + 0.799 0.596 -0.850
ENSG00000166123 E020 45.4349978 0.0006134659 0.0004628868 0.008228522 16 46928907 46931289 2383 + 1.593 1.713 0.409

Help

Please Click HERE to learn more details about the results from DEXseq.