ENSG00000166140

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000299173 ENSG00000166140 No_inf pgKDN_inf ZFYVE19 protein_coding protein_coding 12.38043 13.76256 10.64994 1.120998 1.846125 -0.3695978 0.5477125 1.00390827 0.0000000 0.59162361 0.0000000 -6.6637833 0.03531667 0.068400 0.000000 -0.068400 0.547846802 0.002607007 FALSE TRUE
ENST00000355341 ENSG00000166140 No_inf pgKDN_inf ZFYVE19 protein_coding protein_coding 12.38043 13.76256 10.64994 1.120998 1.846125 -0.3695978 0.8878891 0.07749023 1.8638365 0.07749023 0.2343986 4.4207293 0.08922500 0.005575 0.197075 0.191500 0.002607007 0.002607007 FALSE TRUE
ENST00000560078 ENSG00000166140 No_inf pgKDN_inf ZFYVE19 protein_coding retained_intron 12.38043 13.76256 10.64994 1.120998 1.846125 -0.3695978 0.8553784 0.60381816 0.8996549 0.22020299 0.1858419 0.5675080 0.07766667 0.040850 0.087700 0.046850 0.764462735 0.002607007 FALSE TRUE
ENST00000563530 ENSG00000166140 No_inf pgKDN_inf ZFYVE19 protein_coding protein_coding_CDS_not_defined 12.38043 13.76256 10.64994 1.120998 1.846125 -0.3695978 0.2953736 0.00000000 0.8861209 0.00000000 0.8861209 6.4856215 0.02054167 0.000000 0.061625 0.061625 0.818774885 0.002607007 FALSE FALSE
ENST00000564258 ENSG00000166140 No_inf pgKDN_inf ZFYVE19 protein_coding protein_coding 12.38043 13.76256 10.64994 1.120998 1.846125 -0.3695978 0.5313569 0.48816135 0.0000000 0.28539014 0.0000000 -5.6385412 0.05013333 0.031900 0.000000 -0.031900 0.572982845 0.002607007 FALSE TRUE
ENST00000566767 ENSG00000166140 No_inf pgKDN_inf ZFYVE19 protein_coding protein_coding 12.38043 13.76256 10.64994 1.120998 1.846125 -0.3695978 1.7223199 3.21562264 0.6344910 1.39238662 0.6344910 -2.3233455 0.11203333 0.213575 0.044125 -0.169450 0.424687848 0.002607007   FALSE
ENST00000567756 ENSG00000166140 No_inf pgKDN_inf ZFYVE19 protein_coding nonsense_mediated_decay 12.38043 13.76256 10.64994 1.120998 1.846125 -0.3695978 0.1601243 0.00000000 0.4803729 0.00000000 0.4803729 5.6158073 0.02033333 0.000000 0.061000 0.061000 0.834289373 0.002607007 FALSE FALSE
ENST00000569057 ENSG00000166140 No_inf pgKDN_inf ZFYVE19 protein_coding nonsense_mediated_decay 12.38043 13.76256 10.64994 1.120998 1.846125 -0.3695978 3.1509138 2.69589663 3.2259442 1.05909669 1.1947668 0.2580800 0.23029167 0.184625 0.294450 0.109825 0.860674072 0.002607007 FALSE TRUE
ENST00000570108 ENSG00000166140 No_inf pgKDN_inf ZFYVE19 protein_coding protein_coding 12.38043 13.76256 10.64994 1.120998 1.846125 -0.3695978 0.2820880 0.84626390 0.0000000 0.49365482 0.0000000 -6.4199836 0.02251667 0.067550 0.000000 -0.067550 0.589457109 0.002607007 FALSE TRUE
ENST00000570162 ENSG00000166140 No_inf pgKDN_inf ZFYVE19 protein_coding retained_intron 12.38043 13.76256 10.64994 1.120998 1.846125 -0.3695978 0.6607272 1.58247895 0.2099194 0.37724913 0.2099194 -2.8562277 0.05035833 0.123675 0.015850 -0.107825 0.203653642 0.002607007 FALSE FALSE
MSTRG.9348.15 ENSG00000166140 No_inf pgKDN_inf ZFYVE19 protein_coding   12.38043 13.76256 10.64994 1.120998 1.846125 -0.3695978 0.6504808 0.30176805 0.1664037 0.30176805 0.1664037 -0.8215919 0.06452500 0.028400 0.011575 -0.016825 0.998457492 0.002607007 FALSE TRUE
MSTRG.9348.5 ENSG00000166140 No_inf pgKDN_inf ZFYVE19 protein_coding   12.38043 13.76256 10.64994 1.120998 1.846125 -0.3695978 2.0874117 2.45453738 1.4555318 0.33804836 0.3209652 -0.7498926 0.17424167 0.189100 0.148750 -0.040350 0.884513767 0.002607007 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000166140 E001 0.0000000       15 40807086 40807088 3 +      
ENSG00000166140 E002 2.5311686 0.0058916606 0.007194850 0.06423556 15 40807089 40807233 145 + 0.725 0.352 -1.784
ENSG00000166140 E003 1.5796276 0.0565352846 0.199909459 0.48172267 15 40807234 40807235 2 + 0.518 0.310 -1.141
ENSG00000166140 E004 2.6790088 0.0129645213 0.121691932 0.36925171 15 40807236 40807413 178 + 0.675 0.459 -0.993
ENSG00000166140 E005 0.0000000       15 40807414 40807421 8 +      
ENSG00000166140 E006 1.4653042 0.0765679848 0.647977573 0.85137293 15 40807422 40807589 168 + 0.435 0.352 -0.462
ENSG00000166140 E007 2.0747358 0.0155234176 0.389663147 0.67532638 15 40807590 40807641 52 + 0.555 0.426 -0.632
ENSG00000166140 E008 1.2242165 0.0106575798 0.625083171 0.83862013 15 40807642 40807659 18 + 0.387 0.310 -0.462
ENSG00000166140 E009 1.0987820 0.0111710700 0.425708014 0.70473120 15 40807660 40807671 12 + 0.387 0.263 -0.784
ENSG00000166140 E010 0.9716457 0.0120683843 0.252709051 0.54411796 15 40807672 40807676 5 + 0.387 0.211 -1.199
ENSG00000166140 E011 0.9716457 0.0120683843 0.252709051 0.54411796 15 40807677 40807733 57 + 0.387 0.211 -1.199
ENSG00000166140 E012 0.3638483 0.0171621398 0.405193660   15 40807734 40807756 23 + 0.197 0.082 -1.463
ENSG00000166140 E013 0.7164944 0.0142703590 0.040371905 0.19484728 15 40807757 40807762 6 + 0.387 0.082 -2.784
ENSG00000166140 E014 0.8341250 0.0125373321 0.018242758 0.11928552 15 40807763 40807767 5 + 0.435 0.082 -3.047
ENSG00000166140 E015 1.8071555 0.0604612590 0.027379566 0.15406255 15 40807768 40807791 24 + 0.619 0.263 -1.922
ENSG00000166140 E016 2.2888281 0.0249368779 0.008012089 0.06920473 15 40807792 40807821 30 + 0.701 0.310 -1.948
ENSG00000166140 E017 3.2769941 0.0047192501 0.031165887 0.16645880 15 40807822 40807868 47 + 0.770 0.489 -1.228
ENSG00000166140 E018 0.6089622 0.0148486753 0.427044147 0.70562173 15 40807869 40807894 26 + 0.270 0.151 -1.047
ENSG00000166140 E019 3.5661040 0.0044097786 0.779408043 0.91499838 15 40807895 40808043 149 + 0.675 0.637 -0.163
ENSG00000166140 E020 3.0531295 0.0048986825 0.329699281 0.62213984 15 40808044 40808075 32 + 0.675 0.544 -0.578
ENSG00000166140 E021 3.5496541 0.0049594678 0.516700012 0.77240773 15 40808076 40808120 45 + 0.701 0.616 -0.363
ENSG00000166140 E022 4.9474580 0.0033851344 0.350314600 0.64055694 15 40808121 40808254 134 + 0.701 0.808 0.431
ENSG00000166140 E023 2.7372689 0.0063248526 0.149546612 0.41184880 15 40808255 40808378 124 + 0.435 0.637 0.953
ENSG00000166140 E024 10.2730001 0.0016751369 0.170437236 0.44263418 15 40808379 40808918 540 + 0.970 1.088 0.434
ENSG00000166140 E025 3.4512497 0.0046153806 0.752528734 0.90253246 15 40808919 40809012 94 + 0.619 0.658 0.166
ENSG00000166140 E026 2.5914994 0.1774552528 0.695854883 0.87591284 15 40809013 40809118 106 + 0.518 0.570 0.241
ENSG00000166140 E027 4.4277754 0.0269226674 0.932986170 0.98062118 15 40809119 40809155 37 + 0.725 0.731 0.024
ENSG00000166140 E028 6.6970638 0.0022414086 0.102632106 0.33492830 15 40809156 40809240 85 + 0.770 0.940 0.660
ENSG00000166140 E029 1.6059723 0.1534918201 0.845530521 0.94508247 15 40809241 40809407 167 + 0.387 0.426 0.217
ENSG00000166140 E030 6.0600821 0.0057091351 0.439741634 0.71565879 15 40809408 40809458 51 + 0.790 0.873 0.322
ENSG00000166140 E031 9.5522795 0.0048897062 0.083174327 0.29717947 15 40809852 40809970 119 + 0.913 1.073 0.594
ENSG00000166140 E032 0.1170040 0.0116719055 0.388194751   15 40809971 40810070 100 + 0.110 0.000 -8.764
ENSG00000166140 E033 4.6090411 0.0035730835 0.055481247 0.23465539 15 40810071 40810080 10 + 0.588 0.822 0.971
ENSG00000166140 E034 11.4158975 0.0012707250 0.031273070 0.16689905 15 40810081 40810216 136 + 0.970 1.150 0.657
ENSG00000166140 E035 11.3241295 0.0015773111 0.972080596 0.99476602 15 40810649 40810757 109 + 1.087 1.081 -0.020
ENSG00000166140 E036 1.1321763 0.0109548787 0.042483998 0.20085308 15 40810758 40811074 317 + 0.110 0.426 2.538
ENSG00000166140 E037 9.9664822 0.0034704653 0.967489591 0.99341205 15 40812699 40812902 204 + 1.032 1.033 0.005
ENSG00000166140 E038 0.7342435 0.0137581708 0.703032926 0.87919127 15 40813323 40813337 15 + 0.270 0.211 -0.462
ENSG00000166140 E039 9.9464755 0.0017590384 0.524427903 0.77753785 15 40813338 40813417 80 + 1.066 1.008 -0.212
ENSG00000166140 E040 1.4838472 0.0842403143 0.605240180 0.82795678 15 40813418 40813662 245 + 0.332 0.426 0.538
ENSG00000166140 E041 0.7352509 0.0137310413 0.703221890 0.87921483 15 40813663 40813712 50 + 0.270 0.211 -0.462
ENSG00000166140 E042 8.4366252 0.0018890624 0.092763280 0.31625125 15 40813713 40813811 99 + 1.055 0.897 -0.588
ENSG00000166140 E043 10.7082384 0.0012966681 0.950965694 0.98754784 15 40813943 40814070 128 + 1.066 1.058 -0.028
ENSG00000166140 E044 1.5957463 0.0087303977 0.775952269 0.91395959 15 40814071 40814147 77 + 0.435 0.391 -0.240
ENSG00000166140 E045 17.2165599 0.0009713168 0.055016671 0.23366164 15 40814148 40815084 937 + 1.170 1.300 0.460

Help

Please Click HERE to learn more details about the results from DEXseq.