ENSG00000166377

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000307671 ENSG00000166377 No_inf pgKDN_inf ATP9B protein_coding protein_coding 24.45583 24.5355 20.6639 1.413266 1.953562 -0.2476478 5.718631 2.536850 7.731884 0.1711556 0.8842692 1.6039704 0.26365000 0.104925 0.399375 0.294450 0.02834626 0.02834626 FALSE TRUE
ENST00000586722 ENSG00000166377 No_inf pgKDN_inf ATP9B protein_coding protein_coding 24.45583 24.5355 20.6639 1.413266 1.953562 -0.2476478 8.152987 9.512069 6.782313 0.7395909 0.9849066 -0.4873722 0.33730833 0.387575 0.324750 -0.062825 0.82434680 0.02834626 FALSE FALSE
ENST00000588895 ENSG00000166377 No_inf pgKDN_inf ATP9B protein_coding nonsense_mediated_decay 24.45583 24.5355 20.6639 1.413266 1.953562 -0.2476478 2.150976 1.634915 0.563586 0.9805067 0.5635860 -1.5199313 0.07309167 0.066100 0.028550 -0.037550 0.83076657 0.02834626 FALSE FALSE
ENST00000590477 ENSG00000166377 No_inf pgKDN_inf ATP9B protein_coding nonsense_mediated_decay 24.45583 24.5355 20.6639 1.413266 1.953562 -0.2476478 3.956505 5.290399 2.599552 0.4786373 1.0386964 -1.0222991 0.15050833 0.214850 0.113575 -0.101275 0.64717558 0.02834626 FALSE TRUE
MSTRG.14100.15 ENSG00000166377 No_inf pgKDN_inf ATP9B protein_coding   24.45583 24.5355 20.6639 1.413266 1.953562 -0.2476478 2.424906 4.019677 1.490722 0.7255550 1.4907222 -1.4250075 0.09383333 0.165500 0.063025 -0.102475 0.17180795 0.02834626 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000166377 E001 0.0000000       18 79069285 79069391 107 +      
ENSG00000166377 E002 0.1170040 0.0117485847 0.6997562885   18 79069392 79069393 2 + 0.084 0.000 -9.655
ENSG00000166377 E003 0.1170040 0.0117485847 0.6997562885   18 79069394 79069396 3 + 0.084 0.000 -12.402
ENSG00000166377 E004 0.5957789 0.1548595619 0.3418961883 0.6333228815 18 79069397 79069405 9 + 0.269 0.107 -1.620
ENSG00000166377 E005 0.5957789 0.1548595619 0.3418961883 0.6333228815 18 79069406 79069407 2 + 0.269 0.107 -1.620
ENSG00000166377 E006 1.3395900 0.0101260646 0.8959781840 0.9657808658 18 79069408 79069481 74 + 0.359 0.379 0.116
ENSG00000166377 E007 1.4866486 0.0098202667 0.1109655710 0.3496621353 18 79069482 79069529 48 + 0.269 0.510 1.378
ENSG00000166377 E008 0.1186381 0.0118652577 0.6997581156   18 79077982 79078157 176 + 0.084 0.000 -12.402
ENSG00000166377 E009 0.0000000       18 79087307 79087314 8 +      
ENSG00000166377 E010 0.0000000       18 79087315 79087678 364 +      
ENSG00000166377 E011 0.0000000       18 79095633 79095762 130 +      
ENSG00000166377 E012 0.7428375 0.0137060290 0.2580607572 0.5503241816 18 79096476 79096483 8 + 0.155 0.326 1.378
ENSG00000166377 E013 5.4447862 0.0026493612 0.1652953734 0.4349224642 18 79096484 79096649 166 + 0.872 0.715 -0.622
ENSG00000166377 E014 7.9995969 0.0018262724 0.2389249052 0.5279045229 18 79110355 79110505 151 + 1.001 0.886 -0.429
ENSG00000166377 E015 4.8029954 0.0288532727 0.0308354980 0.1652894680 18 79113241 79113309 69 + 0.871 0.579 -1.206
ENSG00000166377 E016 5.0290460 0.0039198060 0.0029871355 0.0344395394 18 79113310 79113354 45 + 0.908 0.546 -1.496
ENSG00000166377 E017 1.0868896 0.0113096580 0.5383051056 0.7871254430 18 79114994 79116082 1089 + 0.359 0.264 -0.621
ENSG00000166377 E018 5.5191699 0.0530874228 0.0301690952 0.1633598264 18 79126267 79126375 109 + 0.930 0.610 -1.291
ENSG00000166377 E019 3.3948934 0.0827625297 0.5357583964 0.7853253079 18 79143802 79143860 59 + 0.687 0.579 -0.469
ENSG00000166377 E020 0.3817870 0.4966236440 0.2009169768   18 79143861 79144286 426 + 0.000 0.264 12.835
ENSG00000166377 E021 0.0000000       18 79154502 79154503 2 +      
ENSG00000166377 E022 1.8183946 0.1505417449 0.5215355417 0.7753643054 18 79154504 79154534 31 + 0.498 0.379 -0.623
ENSG00000166377 E023 2.0463215 0.0704166207 0.1379341516 0.3952319189 18 79154535 79154555 21 + 0.579 0.326 -1.323
ENSG00000166377 E024 0.0000000       18 79173702 79173733 32 +      
ENSG00000166377 E025 3.8798199 0.0134936511 0.3138312177 0.6069774402 18 79176813 79176907 95 + 0.741 0.610 -0.555
ENSG00000166377 E026 4.7218076 0.0031048738 0.1983262591 0.4797510072 18 79193183 79193263 81 + 0.818 0.665 -0.622
ENSG00000166377 E027 0.0000000       18 79194386 79194492 107 +      
ENSG00000166377 E028 0.0000000       18 79194493 79194608 116 +      
ENSG00000166377 E029 0.0000000       18 79206936 79206936 1 +      
ENSG00000166377 E030 3.0141935 0.0048043701 0.1131094204 0.3538611246 18 79206937 79206976 40 + 0.687 0.470 -0.984
ENSG00000166377 E031 2.3144091 0.0070622066 0.9048864343 0.9695449990 18 79206977 79207012 36 + 0.527 0.510 -0.081
ENSG00000166377 E032 0.0000000       18 79209548 79209722 175 +      
ENSG00000166377 E033 3.0303077 0.0051144360 0.4498394730 0.7233859726 18 79213962 79214038 77 + 0.647 0.546 -0.452
ENSG00000166377 E034 7.0672983 0.0047242547 0.9555828506 0.9892827964 18 79253381 79253541 161 + 0.908 0.902 -0.022
ENSG00000166377 E035 0.1176306 0.0117938199 0.6997390443   18 79253542 79255271 1730 + 0.084 0.000 -12.402
ENSG00000166377 E036 0.1268540 0.0123579329 0.4116675959   18 79261555 79261605 51 + 0.000 0.107 12.000
ENSG00000166377 E037 8.0187140 0.0250642752 0.5657066856 0.8044337610 18 79277054 79277196 143 + 0.982 0.917 -0.243
ENSG00000166377 E038 0.0000000       18 79277197 79277268 72 +      
ENSG00000166377 E039 0.0000000       18 79299899 79299991 93 +      
ENSG00000166377 E040 5.9800476 0.0024487007 0.8430708368 0.9438151506 18 79303604 79303716 113 + 0.832 0.854 0.083
ENSG00000166377 E041 6.4882218 0.0596341955 0.5393885859 0.7878079452 18 79306986 79307111 126 + 0.832 0.917 0.325
ENSG00000166377 E042 7.9843376 0.0020613381 0.0945704143 0.3199849889 18 79307112 79307189 78 + 0.872 1.032 0.601
ENSG00000166377 E043 6.6011278 0.0227430092 0.5416158349 0.7892442570 18 79307190 79307234 45 + 0.846 0.917 0.271
ENSG00000166377 E044 0.0000000       18 79307235 79307440 206 +      
ENSG00000166377 E045 11.3165148 0.0589015336 0.8385164162 0.9421067966 18 79329141 79329302 162 + 1.100 1.075 -0.091
ENSG00000166377 E046 6.4062056 0.0035845446 0.0928725012 0.3165635770 18 79330012 79330104 93 + 0.941 0.759 -0.704
ENSG00000166377 E047 0.0000000       18 79332828 79332853 26 +      
ENSG00000166377 E048 0.0000000       18 79332854 79333000 147 +      
ENSG00000166377 E049 0.0000000       18 79336626 79336627 2 +      
ENSG00000166377 E050 5.2166386 0.0082576943 0.4140023685 0.6944111639 18 79336628 79336711 84 + 0.832 0.738 -0.376
ENSG00000166377 E051 3.5309839 0.0042822704 0.8197945885 0.9345043758 18 79337279 79337316 38 + 0.667 0.638 -0.124
ENSG00000166377 E052 8.5529616 0.0019872548 0.5369981709 0.7861261427 18 79337317 79337449 133 + 0.951 1.009 0.213
ENSG00000166377 E053 9.4629652 0.0266515424 0.1000451417 0.3305227404 18 79342268 79342366 99 + 0.930 1.104 0.641
ENSG00000166377 E054 0.0000000       18 79344139 79344264 126 +      
ENSG00000166377 E055 8.2454771 0.0017373381 0.0299691466 0.1628898471 18 79344265 79344327 63 + 0.859 1.065 0.768
ENSG00000166377 E056 6.3490891 0.0024788400 0.6997565248 0.8776083250 18 79344328 79344354 27 + 0.846 0.886 0.156
ENSG00000166377 E057 13.5708425 0.0011211272 0.3628523035 0.6519203440 18 79345428 79345572 145 + 1.129 1.198 0.248
ENSG00000166377 E058 7.4554945 0.0019110105 0.5254637818 0.7782126729 18 79345775 79345839 65 + 0.896 0.959 0.236
ENSG00000166377 E059 0.0000000       18 79345840 79345840 1 +      
ENSG00000166377 E060 5.2132016 0.0030893578 0.4059903842 0.6886616361 18 79347770 79347807 38 + 0.832 0.738 -0.376
ENSG00000166377 E061 8.9824106 0.0016027507 0.3229444820 0.6157488491 18 79347808 79347906 99 + 1.036 0.945 -0.338
ENSG00000166377 E062 4.8391350 0.0029893387 0.1574831193 0.4241355720 18 79347907 79347925 19 + 0.832 0.665 -0.676
ENSG00000166377 E063 5.6944413 0.0026948591 0.1884804857 0.4668874483 18 79348132 79348196 65 + 0.884 0.738 -0.576
ENSG00000166377 E064 4.8745372 0.0227489594 0.8975214392 0.9662154650 18 79359354 79359395 42 + 0.774 0.759 -0.058
ENSG00000166377 E065 6.8515152 0.0039406166 0.4845027362 0.7486583365 18 79359396 79359462 67 + 0.859 0.931 0.275
ENSG00000166377 E066 2.5159473 0.0221547202 0.0002281270 0.0046622976 18 79359463 79361738 2276 + 0.216 0.759 2.881
ENSG00000166377 E067 0.0000000       18 79361739 79361992 254 +      
ENSG00000166377 E068 3.5116114 0.0042233936 0.0000292626 0.0008489775 18 79361993 79364284 2292 + 0.317 0.870 2.580
ENSG00000166377 E069 0.9870424 0.0428933945 0.3015060791 0.5946330080 18 79372390 79372558 169 + 0.216 0.379 1.116
ENSG00000166377 E070 0.6152580 0.0142938338 0.4627121016 0.7329898734 18 79372559 79372685 127 + 0.155 0.264 0.963
ENSG00000166377 E071 0.6087413 0.0144122797 0.8745564438 0.9571129962 18 79372686 79372824 139 + 0.216 0.193 -0.207
ENSG00000166377 E072 5.6001363 0.0028151534 0.7655460345 0.9088680989 18 79372825 79372882 58 + 0.832 0.800 -0.129
ENSG00000166377 E073 14.9938754 0.0012363448 0.7822736731 0.9162457662 18 79373898 79374101 204 + 1.193 1.213 0.072
ENSG00000166377 E074 0.0000000       18 79374102 79374275 174 +      
ENSG00000166377 E075 0.3629044 0.0166260485 0.7597341085   18 79375394 79375426 33 + 0.155 0.107 -0.622
ENSG00000166377 E076 52.6779208 0.0003471373 0.0648258736 0.2565784188 18 79377247 79378354 1108 + 1.695 1.765 0.238

Help

Please Click HERE to learn more details about the results from DEXseq.